World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
89
Citations
29188
World Ranking
2552
National Ranking
180

Research.com Recognitions

  • 2005 - Fellow of the Royal Society, United Kingdom
  • 1999 - Fellow of the Royal Society of Edinburgh

Overview

Colin Watts is affiliated with the University of Birmingham in the United Kingdom. Their research primarily spans the fields of Immunology and Microbiology, as well as Biochemistry, Genetics and Molecular Biology. Within these broader areas, their work focuses on subfields including Immunology, Molecular Biology, Oncology, Parasitology, and Hematology.

The scientist's research interests cover a range of topics related to immune cell functions and interactions, immunotherapy and immune responses, peptidase inhibition and analysis, ubiquitin and proteasome pathways, as well as studies on Toxoplasma gondii, immunodeficiency and autoimmune disorders, and hematopoietic stem cell transplantation.

Colin Watts has published in multiple academic venues. Their recent publications include:

  • Lysosomes and lysosome-related organelles in immune responses, 2022, FEBS Open Bio
  • Discovery and Differential Processing of HLA Class II-Restricted Minor Histocompatibility Antigen LB-PIP4K2A-1S and Its Allelic Variant by Asparagine Endopeptidase, 2020, Frontiers in Immunology
  • The EGFRvIII transcriptome in glioblastoma, a meta-omics analysis, 2022, WFNOS 2022 Abstract Book
  • Radiotherapy resistance driven by Asparagine endopeptidase through ATR pathway modulation in breast cancer, 2025, Journal of Experimental & Clinical Cancer Research
  • 159  Lessons learned initiating a RCT using an approved drug in a new setting (SPRING Study), 2022, Journal of Neurology Neurosurgery & Psychiatry

Frequent co-authors in their research collaborations include Macarena Morillo-Huesca, Mercedes Tomé, Pablo Huertas, Gema Moreno-Bueno, and Raúl V. Durán. These collaborations reflect a consistent interdisciplinary engagement within their main areas of study.

Colin Watts has contributed to the fields of Immunology and Molecular Biology over multiple years, with research outputs spanning fundamental immune mechanisms to applications in oncology and infectious diseases.

The scientist has been recognized with prestigious awards, including being named a Fellow of the Royal Society in the United Kingdom in 2005 and a Fellow of the Royal Society of Edinburgh in 1999.

Best Publications

  • Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics

    Andrea Sottoriva;Andrea Sottoriva;Andrea Sottoriva;Inmaculada Spiteri;Sara G. M. Piccirillo;Anestis Touloumis

  • CAPTURE AND PROCESSING OF EXOGENOUS ANTIGENS FOR PRESENTATION ON MHC MOLECULES

    Colin Watts

  • European Association for Neuro-Oncology (EANO) guideline on the diagnosis and treatment of adult astrocytic and oligodendroglial gliomas

    Michael Weller;Martin van den Bent;Jörg C Tonn;Roger Stupp

  • Enhanced detection of circulating tumor DNA by fragment size analysis

    Florent Mouliere;Dineika Chandrananda;Anna M. Piskorz;Elizabeth K. Moore;Elizabeth K. Moore

  • Enhanced Dendritic Cell Antigen Capture via Toll-Like Receptor-Induced Actin Remodeling

    Michele A. West;Robert P. A. Wallin;Robert P. A. Wallin;Robert P. A. Wallin;Stephen P. Matthews;Henrik G. Svensson

  • Distinct endocytotic pathways in epidermal growth factor-stimulated human carcinoma A431 cells.

    M A West;M S Bretscher;C Watts

  • Class I MHC presentation of exogenous soluble antigen via macropinocytosis in bone marrow macrophages

    Christopher C. Norbury;Lindsay J. Hewlett;Alan R. Prescott;Nilabh Shastri

  • Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: a dose escalation, open-label, phase 1/2 trial

    Stéphane Palfi;Jean Marc Gurruchaga;G Scott Ralph;Helene Lepetit

  • EANO-ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up of patients with leptomeningeal metastasis from solid tumours.

    E. Le Rhun;M. Weller;D. Brandsma;M. Van den Bent

  • The coated pit and macropinocytic pathways serve distinct endosome populations

    Lindsay J. Hewlett;Alan R. Prescott;Colin Watts

  • An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation

    Bénédicte Manoury;Eric W. Hewitt;Nick Morrice;Pam M. Dando

  • Constitutive macropinocytosis allows TAP-dependent major histocompatibility compex class I presentation of exogenous soluble antigen by bone marrow-derived dendritic cells

    Christopher C. Norbury;Benedict J. Chambers;Alan R. Prescott;Hans Gustaf Ljunggren

  • Cloning, Isolation, and Characterization of Mammalian Legumain, an Asparaginyl Endopeptidase

    Jinq-May Chen;Pam M. Dando;Neil D. Rawlings;Molly A. Brown

  • Antigen processing and class II MHC peptide-loading compartments in human B-lymphoblastoid cells

    Michele A. West;John M. Lucocq;Colin Watts

  • Longitudinal molecular trajectories of diffuse glioma in adults

    Floris P. Barthel;Kevin C. Johnson;Frederick S. Varn;Anzhela D. Moskalik

  • The exogenous pathway for antigen presentation on major histocompatibility complex class II and CD1 molecules

    Colin Watts

  • Rac is required for constitutive macropinocytosis by dendritic cells but does not control its downregulation.

    Michele A. West;Alan R. Prescott;Eeva-Liisa Eskelinen;Anne J. Ridley

  • Cycling of cell-surface MHC glycoproteins through primaquine-sensitive intracellular compartments

    Pamela A. Reid;Colin Watts

  • Modulation of antigen processing by bound antibodies can boost or suppress class II major histocompatibility complex presentation of different T cell determinants.

    P D Simitsek;D G Campbell;A Lanzavecchia;N Fairweather

  • Bm-CPI-2, a cystatin homolog secreted by the filarial parasite Brugia malayi, inhibits class II MHC-restricted antigen processing.

    Bénédicte Manoury;William F. Gregory;Rick M. Maizels;Colin Watts

Frequent Co-Authors

Stephen B. Dunnett
Stephen B. Dunnett Cardiff University
Alan R. Prescott
Alan R. Prescott University of Dundee
Simon Tavaré
Simon Tavaré Columbia University
Wolfgang Wick
Wolfgang Wick German Cancer Research Center
Pieter Wesseling
Pieter Wesseling University of Amsterdam
Michael Weller
Michael Weller University of Zurich
Antonio Lanzavecchia
Antonio Lanzavecchia Istituto Nazionale Genetica Molecolare
Ultan McDermott
Ultan McDermott AstraZeneca (United Kingdom)
John C. Marioni
John C. Marioni European Bioinformatics Institute
Anne Elizabeth Rosser
Anne Elizabeth Rosser Cardiff University

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