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Molecular Biology

D-Index
55
Citations
16109
World Ranking
2247
National Ranking
1109

Overview

Benjamin P C Chen is affiliated with The University of Texas Southwestern Medical Center in the United States. Their research spans the fields of Medicine and Immunology and Microbiology, with a focus on several subfields including Virology, Immunology, Infectious Diseases, Epidemiology, and Neurology.

The scientist's work covers a range of main research topics, including:

  • HIV Research and Treatment
  • Immune Cell Function and Interaction
  • Cytomegalovirus and herpesvirus research
  • Mosquito-borne diseases and control
  • COVID-19 Clinical Research Studies
  • Long-Term Effects of COVID-19
  • Neuroinflammation and Neurodegeneration Mechanisms

Among the recent papers authored by Benjamin P C Chen are:

  • "Convalescent plasma treatment of severe COVID-19: a propensity score-matched control study," published in 2020 in Nature Medicine
  • "Thousands of conductance levels in memristors integrated on CMOS," published in 2023 in Nature
  • "Viral persistence, reactivation, and mechanisms of long COVID," published in 2023 in eLife
  • "Convalescent plasma treatment of severe COVID-19: A matched control study," published in 2020 in bioRxiv (Cold Spring Harbor Laboratory)
  • "Researching COVID to Enhance Recovery (RECOVER) adult study protocol: Rationale, objectives, and design," published in 2023 in PLoS ONE

Frequent publication venues for this scientist include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Regular and Young Investigator Award Abstracts
  • eLife
  • Nature Communications
  • Viruses

Benjamin P C Chen collaborates regularly with several co-authors, notably:

  • Raymond Alvarez
  • Judith A. Aberg
  • Thomas Huser
  • Alice Sandmeyer
  • Wolfgang Hübner

Best Publications

  • ATM Phosphorylates Histone H2AX in Response to DNA Double-strand Breaks

    Sandeep Burma;Benjamin P. Chen;Michael Murphy;Akihiro Kurimasa

  • Telomere Shortening Triggers Senescence of Human Cells through a Pathway Involving ATM, p53, and p21CIP1, but Not p16INK4a

    Utz Herbig;Wendy A Jobling;Benjamin P.C Chen;David J Chen

  • Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks

    Naoya Uematsu;Eric Weterings;Ken Ichi Yano;Keiko Morotomi-Yano

  • Role of non-homologous end joining (NHEJ) in maintaining genomic integrity

    Sandeep Burma;Benjamin P.C. Chen;David J. Chen

  • Analysis of ATF3, a transcription factor induced by physiological stresses and modulated by gadd153/Chop10.

    Benjamin P C Chen;Curt D. Wolfgang;Tsonwin Hai

  • Ataxia telangiectasia mutated (ATM) is essential for DNA-PKcs phosphorylations at the Thr-2609 cluster upon DNA double strand break.

    Benjamin P.C. Chen;Naoya Uematsu;Junya Kobayashi;Yaniv Lerenthal

  • Cell Cycle Dependence of DNA-dependent Protein Kinase Phosphorylation in Response to DNA Double Strand Breaks

    Benjamin P.C. Chen;Doug W. Chan;Junya Kobayashi;Sandeep Burma

  • DNA microarray analysis of gene expression in endothelial cells in response to 24-h shear stress.

    Benjamin P C Chen;Yi Shuan Li;Yihua Zhao;Kuang Den Chen

  • DNA-PK: A dynamic enzyme in a versatile DSB repair pathway

    Anthony J. Davis;Benjamin P.C. Chen;David J. Chen

  • ATF3 and ATF3 delta Zip. Transcriptional repression versus activation by alternatively spliced isoforms.

    Benjamin P C Chen;Guosheng Liang;James Whelan;Tsonwin Hai

  • Molecular mechanism of endothelial growth arrest by laminar shear stress

    Kurt Lin;Pin Pin Hsu;Benjamin P. Chen;Suli Yuan

  • ATF3 gene. Genomic organization, promoter, and regulation.

    Guosheng Liang;Curt D. Wolfgang;Benjamin P C Chen;Tsu Hua Chen

  • LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration

    Mi Deng;Xun Gui;Jaehyup Kim;Li Xie

  • DNA-PK phosphorylates histone H2AX during apoptotic DNA fragmentation in mammalian cells.

    Bipasha Mukherjee;Chase Kessinger;Junya Kobayashi;Benjamin P.C. Chen

  • CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells

    Jiyeon Kim;Zeping Hu;Ling Cai;Kailong Li

  • Distinct roles for the small GTPases Cdc42 and Rho in endothelial responses to shear stress

    Song Li;Benjamin P.C. Chen;Nobuyoshi Azuma;Ying-Li Hu

  • Identification of transcription factor KLF8 as a downstream target of focal adhesion kinase in its regulation of cyclin D1 and cell cycle progression

    Jihe Zhao;Z. Christine Bian;Kristine Yee;Benjamin P C Chen

  • gadd153/Chop10, a potential target gene of the transcriptional repressor ATF3.

    Curt D. Wolfgang;Benjamin P. C. Chen;Jennifer L. Martindale;Nikki J. Holbrook

  • Shear Stress Activation of SREBP1 in Endothelial Cells Is Mediated by Integrins

    Yi Liu;Benjamin P.-C. Chen;Min Lu;Yi Zhu

  • Akt promotes post-irradiation survival of human tumor cells through initiation, progression, and termination of DNA-PKcs-dependent DNA double-strand break repair.

    Mahmoud Toulany;Kyung Jong Lee;Kazi R. Fattah;Yu Fen Lin

Frequent Co-Authors

David J. Chen
David J. Chen The University of Texas Southwestern Medical Center
Shu Chien
Shu Chien University of California, San Diego
Amelia J. Eisch
Amelia J. Eisch University of Pennsylvania
John Y.-J. Shyy
John Y.-J. Shyy University of California, San Diego
Song Li
Song Li University of California, Los Angeles
John D. Minna
John D. Minna The University of Texas Southwestern Medical Center
Tsonwin Hai
Tsonwin Hai The Ohio State University
Luc Girard
Luc Girard The University of Texas Southwestern Medical Center
Cheng Cheng Zhang
Cheng Cheng Zhang The University of Texas Southwestern Medical Center
Stuart K. Calderwood
Stuart K. Calderwood Beth Israel Deaconess Medical Center

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