D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 44 Citations 7,227 105 World Ranking 1938 National Ranking 980

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Cancer

Molecular biology, Cell killing, Bystander effect, Mitosis and Cell are his primary areas of study. The study incorporates disciplines such as Chinese hamster ovary cell, Mutation, Mutant, Irradiation and DNA repair in addition to Molecular biology. His studies in Chinese hamster ovary cell integrate themes in fields like Nuclear medicine and Hamster.

His Cell killing course of study focuses on Ataxia-telangiectasia and Retinoblastoma and Hereditary Retinoblastoma. His Mitosis study incorporates themes from Lethality, Cell cycle, X chromosome and Chinese hamster. As part of his studies on Cell, he often connects relevant subjects like Sister chromatid exchange.

His most cited work include:

  • Induction of Sister Chromatid Exchanges by Extremely Low Doses of α-Particles (852 citations)
  • Unexpected sensitivity to the induction of mutations by very low doses of alpha-particle radiation: evidence for a bystander effect. (233 citations)
  • Ku70: A Candidate Tumor Suppressor Gene for Murine T Cell Lymphoma (219 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Molecular biology, Genetics, Cell culture, Cell cycle and Cell killing. His studies deal with areas such as Cell, Chinese hamster ovary cell, Sister chromatids, DNA repair and Fibroblast as well as Molecular biology. His work in Genetics covers topics such as Irradiation which are related to areas like Nuclear medicine.

The Cell culture study combines topics in areas such as Malignant transformation, Bystander effect, Immunology and Cytotoxic T cell, In vitro. His Cell cycle study integrates concerns from other disciplines, such as Tumor suppressor gene, Cancer research and Mitosis, Cell biology. His work deals with themes such as Retinoblastoma, Radiosensitivity, Proband and Ataxia-telangiectasia, which intersect with Cell killing.

He most often published in these fields:

  • Molecular biology (66.06%)
  • Genetics (29.36%)
  • Cell culture (28.44%)

What were the highlights of his more recent work (between 2005-2017)?

  • Molecular biology (66.06%)
  • Genetics (29.36%)
  • Radiosensitivity (11.93%)

In recent papers he was focusing on the following fields of study:

Hatsumi Nagasawa mostly deals with Molecular biology, Genetics, Radiosensitivity, Cell killing and Homologous recombination. His Molecular biology research includes themes of Cell, Cell culture, Proband, DNA damage and DNA repair. His work on DNA as part of general Genetics research is frequently linked to Low dose rate irradiation and γ h2ax foci, thereby connecting diverse disciplines of science.

His research in DNA intersects with topics in Chinese hamster ovary cell and Cell biology. His Cell killing research incorporates elements of Retinoblastoma, DNA-PKcs, Cell cycle and Kinase activity. His biological study spans a wide range of topics, including Sister chromatid exchange and Chromatid.

Between 2005 and 2017, his most popular works were:

  • Repression of mutagenesis by Rad51D-mediated homologous recombination (76 citations)
  • Levels of γ-H2AX Foci after Low-Dose-Rate Irradiation Reveal a DNA DSB Rejoining Defect in Cells from Human ATM Heterozygotes in Two AT Families and in Another Apparently Normal Individual (61 citations)
  • Hypoxia accelerates cancer invasion of hepatoma cells by upregulating MMP expression in an HIF-1α-independent manner (56 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Cancer

Hatsumi Nagasawa mainly focuses on Molecular biology, Radiosensitivity, Cell killing, DNA repair and DNA damage. As a part of the same scientific family, Hatsumi Nagasawa mostly works in the field of Molecular biology, focusing on Genetics and, on occasion, Irradiation. His Radiosensitivity research is multidisciplinary, relying on both DNA-PKcs, Protein kinase A, Non-homologous end joining, Kinase activity and Chromosome instability.

His research investigates the connection with Cell killing and areas like Germline mutation which intersect with concerns in Cell cycle. His studies in Cell cycle integrate themes in fields like Tumor progression, Cancer research and Tumor hypoxia. His research integrates issues of Gene duplication, Mutagenesis, Chromatid and DNA replication in his study of DNA damage.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Induction of sister chromatid exchanges by extremely low doses of alpha-particles.

Hatsumi Nagasawa;John B. Little.
Cancer Research (1992)

1296 Citations

Unexpected sensitivity to the induction of mutations by very low doses of alpha-particle radiation: evidence for a bystander effect.

Hatsumi Nagasawa;John B. Little.
Radiation Research (1999)

369 Citations

Ku70: A Candidate Tumor Suppressor Gene for Murine T Cell Lymphoma

Gloria C. Li;Honghai Ouyang;Xiaoling Li;Hatsumi Nagasawa.
Molecular Cell (1998)

335 Citations

Radiation-induced genomic instability: delayed mutagenic and cytogenetic effects of X rays and alpha particles.

John B. Little;Hatsumi Nagasawa;Tracy Pfenning;Helen Vetrovs.
Radiation Research (1997)

295 Citations

Heat-induced lethality and chromosomal damage in synchronized Chinese hamster cells treated with 5-bromodeoxyuridine.

Dewey Wc;Westra A;Miller Hh;Nagasawa H.
International Journal of Radiation Biology (1971)

231 Citations

HPRT mutants induced in bystander cells by very low fluences of alpha particles result primarily from point mutations.

Lihong Huo;Hatsumi Nagasawa;John B. Little.
Radiation Research (2001)

187 Citations

Silencing Expression of the Catalytic Subunit of DNA-dependent Protein Kinase by Small Interfering RNA Sensitizes Human Cells for Radiation-induced Chromosome Damage, Cell Killing, and Mutation

Yuanlin Peng;Qinming Zhang;Hatsumi Nagasawa;Ryuichi Okayasu.
Cancer Research (2002)

187 Citations

Bystander effects: intercellular transmission of radiation damage signals.

J. B. Little;E. I. Azzam;S. M. de Toledo;H. Nagasawa (Invited).
Radiation Protection Dosimetry (2002)

176 Citations

ABSENCE OF RADIATION-INDUCED G1 ARREST IN TWO CLOSELY RELATED HUMAN LYMPHOBLAST CELL LINES THAT DIFFER IN P53 STATUS

John B. Little;Hatsumi Nagasawa;Peter C. Keng;Yongjia Yu.
Journal of Biological Chemistry (1995)

168 Citations

Increased bystander mutagenic effect in DNA double-strand break repair-deficient mammalian cells

H. Nagasawa;L. Huo;J. B. Little.
International Journal of Radiation Biology (2003)

158 Citations

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