World's Best Scientists 2026 revealed!
Giannis Spyrou

Giannis Spyrou

D-Index & Metrics

Biology and Biochemistry

D-Index
47
Citations
8481
World Ranking
18676
National Ranking
293

Giannis Spyrou publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Giannis Spyrou sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 83 publications — 2nd percentile

2% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Giannis Spyrou D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Giannis Spyrou sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 47 D-Index — 6th percentile

6% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Giannis Spyrou is affiliated with Linköping University in Sweden and has contributed to research primarily in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work spans several subfields including Cardiology and Cardiovascular Medicine, Molecular Biology, Genetics, Immunology, and Biotechnology.

The scientist's research topics notably cover cardiac electrophysiology and arrhythmias, atrial fibrillation management and outcomes, microbial inactivation methods, retinal development and disorders, photoreceptor and optogenetics research, advanced fluorescence microscopy techniques, and cardiovascular effects of exercise.

Giannis Spyrou has authored and coauthored several papers published in multiple academic journals. Significant publications include:

  • AAV-mediated ERdj5 overexpression protects against P23H rhodopsin toxicity (2020, Human Molecular Genetics)
  • Deregulation of the Kallikrein Protease Family in the Salivary Glands of the Sjögren's Syndrome ERdj5 Knockout Mouse Model (2021, Frontiers in Immunology)
  • Biochemical response to cryothermal and radiofrequency exposure of the human myocardium at surgical ablation of atrial fibrillation: a randomized controlled trial (2020, Translational Medicine Communications)
  • Sizing Up Extracellular DNA: Instant Chromatin Discharge From Cells When Placed in Serum-Free Conditions (2020, Frontiers in Cell and Developmental Biology)
  • Biochemical response to cryothermal and radiofrequency exposure of the human myocardium at surgical ablation of atrial fibrillation: a randomized controlled trial (2020, Research Square)

Frequent coauthors in their research include Gabriella Boano, Meriam Åström Aneq, Helena Enocsson, Emmanouil Charitakis, and Farkas Vánky. These collaborators appear regularly across several publications.

The venues where Giannis Spyrou commonly publishes reflect a variety of biomedical and clinical research fields. These include:

  • Research Square
  • Human Molecular Genetics
  • Translational Medicine Communications
  • Frontiers in Immunology
  • Frontiers in Cell and Developmental Biology

Best Publications

  • Cloning and Expression of a Novel Mammalian Thioredoxin

    Giannis Spyrou;Eva Enmark;Antonio Miranda-Vizuete;Jan-Åke Gustafsson

  • Thioredoxin-2 (TRX-2) is an essential gene regulating mitochondria-dependent apoptosis.

    Toru Tanaka;Fumihito Hosoi;Yuko Yamaguchi-Iwai;Hajime Nakamura

  • IDENTIFICATION AND FUNCTIONAL CHARACTERIZATION OF A NOVEL MITOCHONDRIAL THIOREDOXIN SYSTEM IN SACCHAROMYCES CEREVISIAE

    José R. Pedrajas;Effie Kosmidou;Antonio Miranda-Vizuete;Jan-Åke Gustafsson

  • The mammalian cytosolic selenoenzyme thioredoxin reductase reduces ubiquinone. A novel mechanism for defense against oxidative stress.

    Ling Xia;Tomas Nordman;Jerker M. Olsson;Anastassios Damdimopoulos

  • Human mitochondrial thioredoxin. Involvement in mitochondrial membrane potential and cell death.

    Anastasios E. Damdimopoulos;Antonio Miranda-Vizuete;Markku Pelto-Huikko;Jan Åke Gustafsson

  • The orphan nuclear receptor SHP inhibits agonist-dependent transcriptional activity of estrogen receptors ERalpha and ERbeta.

    Lotta Johansson;Jane S. Thomsen;Anastasios E. Damdimopoulos;Giannis Spyrou

  • Mitochondria of Saccharomyces cerevisiae contain one-conserved cysteine type peroxiredoxin with thioredoxin peroxidase activity

    José Rafael Pedrajas;Antonio Miranda-Vizuete;Negin Javanmardy;Jan-Åke Gustafsson

  • Human mitochondrial thioredoxin reductase. cDNA cloning, expression and genomic organization

    Antonio Miranda‐Vizuete;Anastasios E. Damdimopoulos;José Rafael Pedrajas;Jan‐Åke Gustafsson

  • Analysis of the inhibition of mammalian thioredoxin, thioredoxin reductase, and glutaredoxin by cis-diamminedichloroplatinum (II) and its major metabolite, the glutathione-platinum complex.

    Elias S.J. Arnér;Hajime Nakamura;Tetsuro Sasada;Junji Yodoi

  • ERdj5, an endoplasmic reticulum (ER)-resident protein containing DnaJ and thioredoxin domains, is expressed in secretory cells or following ER stress.

    Paula M. Cunnea;Antonio Miranda-Vizuete;Gloria Bertoli;Thomas Simmen

  • The mitochondrial thioredoxin system.

    Antonio Miranda-Vizuete;Anastasios E. Damdimopoulos;Giannis Spyrou

  • Characterization of Sptrx, a Novel Member of the Thioredoxin Family Specifically Expressed in Human Spermatozoa

    Antonio Miranda-Vizuete;Johanna Ljung;Anastasios E. Damdimopoulos;Jan Åke Gustafsson

  • Two AP1 sites binding JunB are essential for human papillomavirus type 18 transcription in keratinocytes.

    F. Thierry;Giannis Spyrou;M. Yaniv;P. Howley

  • Cloning, expression, and characterization of a novel Escherichia coli thioredoxin

    Antonio Miranda-Vizuete;Anastasios E. Damdimopoulos;Jan-Åke Gustafsson;Giannis Spyrou

  • Selenium and the Thioredoxin and Glutaredoxin Systems

    M. Björnstedt;S. Kumar;L. Björkhem;Giannis Spyrou

  • Variations in Jun and Fos protein expression and AP-1 activity in cycling, resting and stimulated fibroblasts

    Dominique Lallemand;Giannis Spyrou;Moshe Yaniv;Curt M Pfarr;Curt M Pfarr

  • Activation of the JNK pathway by distantly related protein kinases, MEKK and MUK.

    S. Hirai;M. Izawa;S. Osada;Giannis Spyrou

  • Overexpression of c-jun, junB, or junD affects cell growth differently.

    M. Castellazzi;Giannis Spyrou;N. La Vista;J-P Dangy

  • NK-lysin, a disulfide-containing effector peptide of T-lymphocytes, is reduced and inactivated by human thioredoxin reductase. Implication for a protective mechanism against NK-lysin cytotoxicity.

    Mats Andersson;Arne Holmgren;Giannis Spyrou

  • Unregulated expression of c-Jun or c-Fos proteins but not Jun D inhibits oestrogen receptor activity in human breast cancer derived cells.

    V. Doucas;Giannis Spyrou;M. Yaniv

Frequent Co-Authors

Antonio Miranda-Vizuete
Antonio Miranda-Vizuete Spanish National Research Council
Jan-Åke Gustafsson
Jan-Åke Gustafsson University of Houston
Arne Holmgren
Arne Holmgren Karolinska Institute
Markku Pelto-Huikko
Markku Pelto-Huikko Tampere University
Peter Reichard
Peter Reichard University of Padua
Elias S.J. Arnér
Elias S.J. Arnér Karolinska Institute
Richard Oko
Richard Oko Queen's University
Eckardt Treuter
Eckardt Treuter Karolinska Institute
Anders Rosén
Anders Rosén Linköping University
Junji Yodoi
Junji Yodoi Kyoto University

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