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Microbiology

D-Index
50
Citations
7642
World Ranking
4493
National Ranking
399

Overview

Bryan Charleston is affiliated with The Pirbright Institute in the United Kingdom, contributing significantly to research within Medicine and Agricultural and Biological Sciences. Their work spans several subfields including Infectious Diseases, Agronomy and Crop Science, Ecology, Evolution, Behavior and Systematics, Immunology, and Epidemiology.

The scientist's research primarily focuses on several main topics such as Animal Disease Management and Epidemiology, Vector-Borne Animal Diseases, SARS-CoV-2 and COVID-19 Research, Viral Infections and Immunology Research, Influenza Virus Research Studies, Viral Infections and Vectors, and Viral Infections and Outbreaks Research.

Key recent publications by Bryan Charleston include the following:

  • A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses (2021, Nature Communications)
  • Evaluation of the immunogenicity of prime-boost vaccination with the replication-deficient viral vectored COVID-19 vaccine candidate ChAdOx1 nCoV-19 (2020, npj Vaccines)
  • Neutralizing antibody activity against 21 SARS-CoV-2 variants in older adults vaccinated with BNT162b2 (2022, Nature Microbiology)
  • Endemic persistence of a highly contagious pathogen: Foot-and-mouth disease in its wildlife host (2021, Science)
  • A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses (2020, bioRxiv (Cold Spring Harbor Laboratory))

Bryan Charleston frequently publishes in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Veterinary Record
  • PLoS Pathogens
  • Frontiers in Immunology
  • npj Vaccines

Common co-authors in their research include:

  • Elma Tchilian
  • Nazia Thakur
  • Joseph Newman
  • Dalan Bailey
  • Eva Pérez-Martín

Best Publications

  • Options for control of foot-and-mouth disease: knowledge, capability and policy

    David J. Paton;Keith J. Sumption;Bryan Charleston

  • A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses.

    T K Tan;P Rijal;P Rijal;R Rahikainen;A H Keeble

  • Establishment of persistent infection with non-cytopathic bovine viral diarrhoea virus in cattle is associated with a failure to induce type I interferon.

    B. Charleston;M. D. Fray;S. Baigent;B. V. Carr

  • Relationship Between Clinical Signs and Transmission of an Infectious Disease and the Implications for Control

    Bryan Charleston;Bartlomies M. Bankowski;Simon Gubbins;Margo E. Chase-Topping

  • Rational Engineering of Recombinant Picornavirus Capsids to Produce Safe, Protective Vaccine Antigen

    Claudine Porta;Abhay Kotecha;Alison Burman;Terry Jackson

  • Bovine γδ T Cells Are a Major Regulatory T Cell Subset

    Efrain Guzman;Jayne Hope;Geraldine Taylor;Adrian L. Smith

  • Global FMD control : is it an option?

    Paul Kitching;Jef Hammond;Martyn Jeggo;Bryan Charleston

  • Evaluation of the immunogenicity of prime-boost vaccination with the replication-deficient viral vectored COVID-19 vaccine candidate ChAdOx1 nCoV-19

    Simon P Graham;Rebecca K McLean;Alexandra J Spencer;Sandra Belij-Rammerstorfer

  • Bovine Viral Diarrhea Virus: Prevention of Persistent Fetal Infection by a Combination of Two Mutations Affecting Erns RNase and Npro Protease

    Gregor Meyers;Andreas Ege;Christiane Fetzer;Martina von Freyburg

  • Validation of an Mx/CAT reporter gene assay for the quantification of bovine type-I interferon

    M.D. Fray;G.E Mann;B. Charleston

  • The Npro product of classical swine fever virus and bovine viral diarrhea virus uses a conserved mechanism to target interferon regulatory factor-3.

    Julian Seago;Louise Hilton;Elizabeth Reid;Virginie Doceul

  • Foot-and-Mouth Disease Virus Can Induce a Specific and Rapid CD4+ T-Cell-Independent Neutralizing and Isotype Class-Switched Antibody Response in Naïve Cattle

    Nicholas Juleff;Miriam Windsor;Eric A. Lefevre;Simon Gubbins

  • Differential effects of bovine viral diarrhoea virus on monocytes and dendritic cells

    E J Glew;B V Carr;L.S Brackenbury;Jayne Hope

  • Chimpanzee Adenovirus Vaccine Provides Multispecies Protection against Rift Valley Fever

    G M Warimwe;J Gesharisha;B V Carr;S Otieno

  • Foot-and-mouth disease virus persists in the light zone of germinal centres.

    Nicholas Juleff;Miriam Windsor;Elizabeth Reid;Julian Seago

  • Structure-based energetics of protein interfaces guides foot-and-mouth disease virus vaccine design.

    A Kotecha;J Seago;K Scott;A Burman

  • Neutralizing antibody activity against 21 SARS-CoV-2 variants in older adults vaccinated with BNT162b2

    Unknown

  • An MHC-restricted CD8+ T-cell response is induced in cattle by foot-and-mouth disease virus (FMDV) infection and also following vaccination with inactivated FMDV

    Efrain Guzman;Geraldine Taylor;Bryan Charleston;Michael A. Skinner

  • Characterization of the porcine neonatal Fc receptor—potential use for trans-epithelial protein delivery

    Catrina M. A. Stirling;Bryan Charleston;Haru Takamatsu;Steven Claypool

  • Efficient production of foot-and-mouth disease virus empty capsids in insect cells following down regulation of 3C protease activity

    Claudine Porta;Xiaodong Xu;Silvia Loureiro;Saravanan Paramasivam

  • An interferon-induced Mx protein: cDNA sequence and high-level expression in the endometrium of pregnant sheep.

    Bryan Charleston;Harriet J. Stewart

  • A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses

    Tiong Kit Tan;Pramila Rijal;Pramila Rijal;Rolle Rahikainen;Anthony H. Keeble

Frequent Co-Authors

Simon Gubbins
Simon Gubbins The Pirbright Institute
Jayne Hope
Jayne Hope University of Edinburgh
Sarah C. Gilbert
Sarah C. Gilbert University of Oxford
David I. Stuart
David I. Stuart University of Oxford
Elizabeth E. Fry
Elizabeth E. Fry University of Oxford
Raymond J. Owens
Raymond J. Owens University of Oxford
Ian M. Jones
Ian M. Jones University of Reading
Luis L. Rodriguez
Luis L. Rodriguez United States Department of Agriculture
Mark E. J. Woolhouse
Mark E. J. Woolhouse University of Edinburgh
David J. Paton
David J. Paton The Pirbright Institute

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