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Hiroshi Kawaguchi

Hiroshi Kawaguchi

D-Index & Metrics

Medicine

D-Index
70
Citations
28347
World Ranking
20050
National Ranking
643

Overview

Hiroshi Kawaguchi is affiliated with the University of Tokyo in Japan and has contributed extensively to the field of medicine, with a focus on surgery, orthopedics and sports medicine, rheumatology, pharmacology, and biomedical engineering. Their research prominently covers topics related to bone health and osteoporosis research, scoliosis diagnosis and treatment, hip and femur fractures, hip disorders and treatments, pelvic and acetabular injuries, osteoarthritis treatment and mechanisms, and lower extremity biomechanics and pathologies.

They have published in frequent venues including:

  • Scientific Reports
  • Journal of Bone and Mineral Metabolism
  • Archives of Osteoporosis
  • Osteoarthritis and Cartilage Open
  • European Spine Journal

Among their recent papers are:

  • Association between types of Modic changes in the lumbar region and low back pain in a large cohort: the Wakayama spine study (2020, European Spine Journal)
  • Relationship of sagittal spinal alignment with low back pain and physical performance in the general population (2021, Scientific Reports)
  • Trends in osteoporosis prevalence over a 10-year period in Japan: the ROAD study 2005-2015 (2022, Journal of Bone and Mineral Metabolism)
  • Serious Adverse Events With Romosozumab Use in Japanese Patients: Need for Clear Formulation of Contraindications Worldwide (2020, Journal of Bone and Mineral Research)
  • Possible involvement of the autonomic nervous system in cervical muscles of patients with myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS) (2021, BMC Musculoskeletal Disorders)

Kawaguchi's body of work includes collaboration with frequent co-authors such as Hiroyuki Oka, Shigeyuki Muraki, Toru Akune, Sakae Tanaka, and Kozo Nakamura, each having worked together on at least 14 to 15 research publications.

In addition to journal articles, Kawaguchi has contributed to book publications, including a title published by Bloomsbury Academic eBooks: "A History of Economic Thought in Japan" (2022).

Best Publications

  • Mutation of the mouse klotho gene leads to a syndrome resembling ageing

    Makoto Kuro-o;Yutaka Matsumura;Hiroki Aizawa;Hiroshi Kawaguchi

  • OARSI guidelines for the non-surgical management of knee osteoarthritis

    Timothy McAlindon;Raveendhara Bannuru;Matthew Sullivan;Nigel Arden

  • PPAR γ insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors

    Toru Akune;Shinsuke Ohba;Satoru Kamekura;Masayuki Yamaguchi

  • Long-term results of double-door laminoplasty for cervical stenotic myelopathy.

    Atsushi Seichi;Katsushi Takeshita;Isao Ohishi;Hiroshi Kawaguchi

  • Stimulation of fracture repair by recombinant human basic fibroblast growth factor in normal and streptozotocin-diabetic rats.

    H Kawaguchi;T Kurokawa;K Hanada;Y Hiyama

  • Prevalence and distribution of intervertebral disc degeneration over the entire spine in a population-based cohort: the Wakayama Spine Study

    M. Teraguchi;N. Yoshimura;H. Hashizume;S. Muraki

  • Esperamicins, a novel class of potent antitumor antibiotics. 3. Structures of esperamicins A1, A2, and A1b

    Jerzy Golik;George Dubay;Gary Groenewold;Hiroshi Kawaguchi

  • Reduced Pain Hypersensitivity and Inflammation in Mice Lacking Microsomal Prostaglandin E Synthase-1

    Daisuke Kamei;Kiyofumi Yamakawa;Yui Takegoshi;Maya Mikami-Nakanishi

  • Esperamicins, a novel class of potent antitumor antibiotics. 2. Structure of esperamicin X

    Jerzy Golik;Jon Clardy;George Dubay;Gary Groenewold

  • Insulin receptor substrate-1 in osteoblast is indispensable for maintaining bone turnover.

    Naoshi Ogata;Daichi Chikazu;Naoto Kubota;Yasuo Terauchi

  • Long-Term Results of ABO-Incompatible Living Kidney Transplantation. A Single-Center Experience

    K. Tanabe;K. Takahashi;K. Sonda;T. Tokumoto

  • Polyion complex micelles from plasmid DNA and poly(ethylene glycol)-poly(L-lysine) block copolymer as serum-tolerable polyplex system: physicochemical properties of micelles relevant to gene transfection efficiency.

    Keiji Itaka;Kyosuke Yamauchi;Atsushi Harada;Kozo Nakamura

  • Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim.

    Toru Akiyama;Phillippe Bouillet;Tsuyoshi Miyazaki;Yuho Kadono

  • In situ single cell observation by fluorescence resonance energy transfer reveals fast intra‐cytoplasmic delivery and easy release of plasmid DNA complexed with linear polyethylenimine

    Keiji Itaka;Atsushi Harada;Yuichi Yamasaki;Kozo Nakamura

  • A new mechanism of bone destruction in rheumatoid arthritis: synovial fibroblasts induce osteoclastogenesis.

    Hiroshi Takayanagi;Hiromi Oda;Seizo Yamamoto;Hiroshi Kawaguchi

  • Strong Static Magnetic Field Stimulates Bone Formation to a Definite Orientation In Vitro and In Vivo

    Hiroko Kotani;Hiroshi Kawaguchi;Takashi Shimoaka;Masakazu Iwasaka

  • Acceleration of fracture healing in nonhuman primates by fibroblast growth factor-2.

    Hiroshi Kawaguchi;Kozo Nakamura;Yasuhiko Tabata;Yoshito Ikada

  • Independent impairment of osteoblast and osteoclast differentiation in klotho mouse exhibiting low-turnover osteopenia

    Hiroshi Kawaguchi;Noriyo Manabe;Chisato Miyaura;Hirotaka Chikuda;Hirotaka Chikuda

  • Mutation of the mouse klotho gene leads to a syndrome resembling ageing

    M. Kuro-o;Y. Matsumura;H. Arawa;H. Kawaguchi

  • Nosocomial infections in adult intensive-care units.

    Shinji Teramoto;Hiroshi Yamamoto;Yasuhiro Yamaguchi;Hiroshi Kawaguchi

Frequent Co-Authors

Kozo Nakamura
Kozo Nakamura Shinshu University
Ung-il Chung
Ung-il Chung University of Tokyo
Sakae Tanaka
Sakae Tanaka University of Tokyo
Kazuhiko Ishihara
Kazuhiko Ishihara University of Tokyo
Takayasu Sakurai
Takayasu Sakurai University of Tokyo
Tsuyoshi Sekitani
Tsuyoshi Sekitani Osaka University
Tomohiro Konno
Tomohiro Konno Tohoku University
Makoto Kuro-o
Makoto Kuro-o Jichi Medical University
Keiji Itaka
Keiji Itaka Tokyo Medical and Dental University

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