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Michael A. McGuckin

Michael A. McGuckin

D-Index & Metrics

Biology and Biochemistry

D-Index
75
Citations
21882
World Ranking
5275
National Ranking
126

Overview

Michael A. McGuckin is affiliated with the University of Melbourne in Australia. Their research spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant focus on immunology, genetics, epidemiology, molecular biology, and surgery. The work is predominantly centered on areas such as diabetes and associated disorders, advanced drug delivery systems, liver disease diagnosis and treatment, gut microbiota and health, Helicobacter pylori-related gastroenterology studies, and IL-33, ST2, and ILC pathways.

Recent publications include:

  • Drug repurposing: Misconceptions, challenges, and opportunities for academic researchers, 2021, Science Translational Medicine
  • Oral Delivery of β-Lactoglobulin-Nanosphere-Encapsulated Resveratrol Alleviates Inflammation in Winnie Mice with Spontaneous Ulcerative Colitis, 2020, Molecular Pharmaceutics
  • Secreted NF-κB suppressive microbial metabolites modulate gut inflammation, 2022, Cell Reports
  • One-Pot Synthesis of pH-Responsive Eudragit-Mesoporous Silica Nanocomposites Enable Colonic Delivery of Glucocorticoids for the Treatment of Inflammatory Bowel Disease, 2020, Advanced Therapeutics
  • pH - Responsive colloidal carriers assembled from β-lactoglobulin and Epsilon poly-L-lysine for oral drug delivery, 2020, Journal of Colloid and Interface Science

The scientist frequently collaborates with several co-authors, including:

  • Sumaira Z. Hasnain (16 publications)
  • Kuan Yau Wong (12 publications)
  • Haressh Sajiir (9 publications)
  • Md. Moniruzzaman (8 publications)
  • Jakob Begun (8 publications)

Publication venues where Michael A. McGuckin's work has appeared repeatedly include:

  • Cellular and Molecular Gastroenterology and Hepatology (3 publications)
  • Nature Communications (2 publications)
  • Gastroenterology (2 publications)
  • Science Translational Medicine (1 publication)
  • Molecular Pharmaceutics (1 publication)

Main fields and subfields of study are closely linked to the thematic focus of their research, reflecting a multidisciplinary approach combining clinical medicine with molecular and cellular biology perspectives.

Best Publications

  • Mucin dynamics and enteric pathogens

    Michael A. McGuckin;Sara K. Lindén;Philip Sutton;Timothy H. Florin

  • Mucolytic bacteria with increased prevalence in IBD mucosa augment in vitro utilization of mucin by other bacteria.

    Chin Wen Png;Sara K Lindén;Kristen S Gilshenan;Erwin G Zoetendal

  • Mucins in the mucosal barrier to infection.

    SK Linden;P Sutton;NG Karlsson;Victoria Korolik

  • Structure and Function of the Polymeric Mucins in Airways Mucus

    David J. Thornton;Karine Rousseau;Michael A. McGuckin

  • Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis.

    Chad K Heazlewood;Matthew C Cook;Rajaraman Eri;Gareth R Price

  • Intestinal barrier dysfunction in inflammatory bowel diseases

    Michael A. McGuckin;Rajaraman Eri;Lisa A. Simms;Lisa A. Simms;Timothy H.J. Florin

  • Effect of long-term, low-dose erythromycin on pulmonary exacerbations among patients with non-cystic fibrosis bronchiectasis: the BLESS randomized controlled trial.

    David J. Serisier;Megan L. Martin;Michael A. McGuckin;Rohan Lourie

  • MUC1 cell surface mucin is a critical element of the mucosal barrier to infection

    Julie L. McAuley;Sara K. Linden;Chin Wen Png;Rebecca M. King

  • MUC13, a Novel Human Cell Surface Mucin Expressed by Epithelial and Hemopoietic Cells

    Stephanie J. Williams;Daniel H. Wreschner;Mai Tran;Helen J. Eyre

  • Two novel mucin genes down-regulated in colorectal cancer identified by differential display.

    Stephanie J. Williams;Michael A. McGuckin;David C. Gotley;Helen J. Eyre

  • Occult axillary node metastases in breast cancer: Their detection and prognostic significance

    M. A. McGuckin;M. C. Cummings;M. D. Walsh;B. G. Hohn

  • MUC1 limits Helicobacter pylori infection both by steric hindrance and by acting as a releasable decoy.

    Sara K. Lindén;Yong H. Sheng;Alison L. Every;Kim M. Miles

  • High Fat Diets Induce Colonic Epithelial Cell Stress and Inflammation that is Reversed by IL-22

    Max Gulhane;Lydia Murray;Rohan Lourie;Hui Tong

  • The interplay between endoplasmic reticulum stress and inflammation

    Sumaira Z Hasnain;Rohan Lourie;Indrajit Das;Alice C-H Chen

  • β-glucan triggers spondylarthritis and Crohn's disease-like ileitis in SKG mice.

    Merja Ruutu;Gethin Thomas;Roland Steck;Mariapia A. Degli-Esposti

  • Oxidative and endoplasmic reticulum stress in β-cell dysfunction in diabetes.

    Sumaira Z Hasnain;Johannes B Prins;Michael A McGuckin

  • Mucin dynamics in intestinal bacterial infection.

    Sara K. Lindén;Sara K. Lindén;Timothy H. J. Florin;Timothy H. J. Florin;Michael A. McGuckin;Michael A. McGuckin

  • Prognostic significance of muc1 epithelial mucin expression in breast cancer

    MA McGuckin;Walsh;Walsh;BG Hohn;BG Hohn;BG Ward;BG Ward

  • Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress.

    Sumaira Z. Hasnain;Danielle J. Borg;Brooke E. Harcourt;Hui Tong

  • A Novel Microbiota Stratification System Predicts Future Exacerbations in Bronchiectasis

    Geraint B. Rogers;Nur Masirah M. Zain;Kenneth D. Bruce;Lucy D. Burr

Frequent Co-Authors

Michael Walsh
Michael Walsh Memorial Sloan Kettering Cancer Center
Geraint B. Rogers
Geraint B. Rogers Flinders University
Mark Morrison
Mark Morrison University of Queensland
Joanne P. Young
Joanne P. Young University of Adelaide
David J. Thornton
David J. Thornton Wellcome Centre for Cell-Matrix Research
Ranjeny Thomas
Ranjeny Thomas University of Queensland
Daniel D. Buchanan
Daniel D. Buchanan University of Melbourne
Mark A. Jenkins
Mark A. Jenkins University of Melbourne
Peter G. Parsons
Peter G. Parsons QIMR Berghofer Medical Research Institute
Glenda C. Gobe
Glenda C. Gobe University of Queensland

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