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Siegfried Labeit
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Biology and Biochemistry
UK
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
104
Citations
33785
World Ranking
1273
National Ranking
69

Siegfried Labeit publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Siegfried Labeit sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 284 publications — 75th percentile

75% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Siegfried Labeit D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Siegfried Labeit sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 104 D-Index — 94th percentile

94% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2025 - Research.com Biology and Biochemistry in United Kingdom Leader Award

Overview

Siegfried Labeit is affiliated with the European Bioinformatics Institute in the United Kingdom and has contributed extensively to research in Medicine, as well as Biochemistry, Genetics, and Molecular Biology. Their work spans multiple subfields, including Molecular Biology, Cardiology and Cardiovascular Medicine, Surgery, Cancer Research, and Physiology.

Their research focuses on topics such as Muscle Physiology and Disorders, Cardiomyopathy and Myosin Studies, Cardiovascular Function and Risk Factors, Viral Infections and Immunology Research, MicroRNA in disease regulation, Muscle metabolism and nutrition, and RNA and protein synthesis mechanisms.

Recent publications by the scientist include:

  • ZSF1 rat as animal model for HFpEF: Development of reduced diastolic function and skeletal muscle dysfunction, 2020, ESC Heart Failure
  • Titin kinase ubiquitination aligns autophagy receptors with mechanical signals in the sarcomere, 2021, EMBO Reports
  • Targeting MuRF1 by small molecules in a HFpEF rat model improves myocardial diastolic function and skeletal muscle contractility, 2022, Journal of Cachexia Sarcopenia and Muscle
  • Empagliflozin Preserves Skeletal Muscle Function in a HFpEF Rat Model, 2022, International Journal of Molecular Sciences
  • Muscle ankyrin repeat protein 1 (MARP1) locks titin to the sarcomeric thin filament and is a passive force regulator, 2021, The Journal of General Physiology

They frequently publish in several scientific journals including:

  • International Journal of Molecular Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Cachexia Sarcopenia and Muscle
  • Cells
  • Frontiers in Genetics

Collaborations are an important aspect of their research, with frequent co-authors including Volker Adams, Anselmo Sigari Moriscot, Antje Schauer, Axel Linke, and Antje Augstein.

Best Publications

  • Titins: Giant Proteins in Charge of Muscle Ultrastructure and Elasticity

    Siegfried Labeit;Bernhard Kolmerer

  • Cloning of the T gene required in mesoderm formation in the mouse

    Bernhard G. Herrmann;Siegfried Labeit;Annemarie Poustka;Thomas R. King

  • The Complete Gene Sequence of Titin, Expression of an Unusual ≈700-kDa Titin Isoform, and Its Interaction With Obscurin Identify a Novel Z-Line to I-Band Linking System

    Marie Louise Bang;Thomas Centner;Friderike Fornoff;Adam J. Geach

  • Mutations of TTN, encoding the giant muscle filament titin, cause familial dilated cardiomyopathy.

    Brenda Gerull;Michael Gramlich;John Atherton;Mark McNabb

  • The Giant Protein Titin: A Major Player in Myocardial Mechanics, Signaling, and Disease

    Henk L. Granzier;Siegfried Labeit

  • Tibial Muscular Dystrophy Is a Titinopathy Caused by Mutations in TTN, the Gene Encoding the Giant Skeletal-Muscle Protein Titin

    Peter Hackman;Anna Vihola;Henna Haravuori;Sylvie Marchand

  • Cardiac myosin binding protein-C gene splice acceptor site mutation is associated with familial hypertrophic cardiomyopathy.

    Bonne G;Bercovici J;Cruaud C

  • Altered Titin Expression, Myocardial Stiffness, and Left Ventricular Function in Patients With Dilated Cardiomyopathy

    Sherif F. Nagueh;Gopi Shah;Yiming Wu;Guillermo Torre-Amione

  • Differential Expression of Cardiac Titin Isoforms and Modulation of Cellular Stiffness

    Olivier Cazorla;A Freiburg;M. Helmes;T Centner

  • Identification of muscle specific ring finger proteins as potential regulators of the titin kinase domain.

    Thomas Centner;Junko Yano;Eiichi Kimura;Abigail S. McElhinny

  • Phosphorylation switches specific for the cardiac isoform of myosin binding protein-C: a modulator of cardiac contraction?

    M. Gautel;O. Zuffardi;A. Freiburg;S. Labeit

  • Towards a molecular understanding of titin.

    S. Labeit;M. Gautel;A. Lakey;J. Trinick

  • Series of Exon-Skipping Events in the Elastic Spring Region of Titin as the Structural Basis for Myofibrillar Elastic Diversity

    Alexandra Freiburg;Karoly Trombitas;Wolfgang Hell;Olivier Cazorla

  • Muscle assembly: a titanic achievement?

    Carol C Gregorio;Henk Granzier;Hiroyuki Sorimachi;Siegfried Labeit

  • Calcium-dependent molecular spring elements in the giant protein titin

    Dietmar Labeit;Kaori Watanabe;Christian Witt;Hideaki Fujita

  • Organization and Sequence of Human Cardiac Myosin Binding Protein C Gene (MYBPC3) and Identification of Mutations Predicted to Produce Truncated Proteins in Familial Hypertrophic Cardiomyopathy

    G Bonne;E Bährend;B Yu

  • The muscle ankyrin repeat proteins: CARP, ankrd2/Arpp and DARP as a family of titin filament-based stress response molecules.

    Melanie K. Miller;Marie Louise Bang;Christian C. Witt;Dietmar Labeit

  • Developmental Control of Titin Isoform Expression and Passive Stiffness in Fetal and Neonatal Myocardium

    Sunshine Lahmers;Yiming Wu;Douglas R. Call;Siegfried Labeit

  • The NH2 terminus of titin spans the Z-disc: its interaction with a novel 19-kD ligand (T-cap) is required for sarcomeric integrity.

    Carol C. Gregorio;Karoly Trombitás;Thomas Centner;Bernhard Kolmerer

  • Protein Kinase A Phosphorylates Titin’s Cardiac-Specific N2B Domain and Reduces Passive Tension in Rat Cardiac Myocytes

    R. Yamasaki;Y. Wu;M. McNabb;M. Greaser

Frequent Co-Authors

Henk Granzier
Henk Granzier University of Arizona
Carol C. Gregorio
Carol C. Gregorio University of Arizona
Hiroyuki Sorimachi
Hiroyuki Sorimachi Tokyo Metropolitan Institute of Medical Science
Mathias Gautel
Mathias Gautel King's College London
Stephanie H. Witt
Stephanie H. Witt Heidelberg University
Carina Wallgren-Pettersson
Carina Wallgren-Pettersson University of Helsinki
Wolfgang A. Linke
Wolfgang A. Linke University of Münster
Koichi Suzuki
Koichi Suzuki University of Tokyo
Nils Erik Gilhus
Nils Erik Gilhus Haukeland University Hospital
Nigel G. Laing
Nigel G. Laing University of Western Australia

External Links

Personal website of Siegfried Labeit

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Best Scientists Citing Siegfried Labeit

Henk Granzier

Henk Granzier

University of Arizona

Publications: 163

Wolfgang A. Linke

Wolfgang A. Linke

University of Münster

Publications: 91

Mathias Gautel

Mathias Gautel

King's College London

Publications: 83

Nigel G. Laing

Nigel G. Laing

University of Western Australia

Publications: 77

Bjarne Udd

Bjarne Udd

University of Helsinki

Publications: 77

Carina Wallgren-Pettersson

Carina Wallgren-Pettersson

University of Helsinki

Publications: 63

Christine E. Seidman

Christine E. Seidman

Harvard University

Publications: 58

Alan H. Beggs

Alan H. Beggs

Harvard Medical School

Publications: 53

Richard L. Lieber

Richard L. Lieber

Northwestern University

Publications: 52

Michael Gotthardt

Michael Gotthardt

University of Bonn

Publications: 50

Dieter O. Fürst

Dieter O. Fürst

University of Bonn

Publications: 44

Marion L. Greaser

Marion L. Greaser

University of Wisconsin–Madison

Publications: 44

Carol C. Gregorio

Carol C. Gregorio

University of Arizona

Publications: 44

Hiroyuki Sorimachi

Hiroyuki Sorimachi

Tokyo Metropolitan Institute of Medical Science

Publications: 41

Jonathan G. Seidman

Jonathan G. Seidman

Harvard University

Publications: 41

Akinori Kimura

Akinori Kimura

Tokyo Medical and Dental University

Publications: 37

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