Michael Gotthardt

Overview

Best Publications

• Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2.

  Marion Trommsdorff;Michael Gotthardt;Thomas Hiesberger;John Shelton

  1482
  Citations

• The Complete Gene Sequence of Titin, Expression of an Unusual ≈700-kDa Titin Isoform, and Its Interaction With Obscurin Identify a Novel Z-Line to I-Band Linking System

  Marie Louise Bang;Thomas Centner;Friderike Fornoff;Adam J. Geach

  821
  Citations

• Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein.

  Olav M. Andersen;Juliane Reiche;Vanessa Schmidt;Michael Gotthardt

  774
  Citations

• LRP: role in vascular wall integrity and protection from atherosclerosis.

  Philippe Boucher;Michael Gotthardt;Wei Ping Li;Richard G W Anderson

  707
  Citations

• Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat

  Thomas J. Park;Jane Reznick;Bethany L. Peterson;Gregory Blass

  589
  Citations

• RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing

  Wei Guo;Sebastian Schafer;Marion L Greaser;Michael H Radke

  588
  Citations

• Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants.

  Astrid Rohlmann;Michael Gotthardt;Robert E Hammer;Joachim Herz

  556
  Citations

• Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction

  Michael Gotthardt;Marion Trommsdorff;Matthew F. Nevitt;John Shelton

  484
  Citations

• Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease

  Angharad M. Roberts;Angharad M. Roberts;James S. Ware;Daniel S. Herman;Daniel S. Herman;Daniel S. Herman;Sebastian Schafer

  472
  Citations

• Smooth muscle-selective deletion of guanylyl cyclase-A prevents the acute but not chronic effects of ANP on blood pressure

  Rita Holtwick;Michael Gotthardt;Boris Skryabin;Martin Steinmetz

  384
  Citations

• Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury

  Pernille Jansen;Klaus Giehl;Klaus Giehl;Jens R Nyengaard;Kenneth Teng

  357
  Citations

• The Reelin Receptor ApoER2 Recruits JNK-interacting Proteins-1 and -2

  Walter Stockinger;Christian Brandes;Daniela Fasching;Marcela Hermann

  292
  Citations

• Platelet-derived growth factor mediates tyrosine phosphorylation of the cytoplasmic domain of the low Density lipoprotein receptor-related protein in caveolae.

  Philippe Boucher;Pingsheng Liu;Michael Gotthardt;Thomas Hiesberger

  248
  Citations

• RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing

  Henrike Maatz;Marvin Jens;Martin Liss;Sebastian Schafer

  209
  Citations

• Clinical genetics and outcome of left ventricular non-compaction cardiomyopathy.

  Farbod Sedaghat-Hamedani;Jan Haas;Feng Zhu;Feng Zhu;Christian Geier

  204
  Citations

• Recessive TTN truncating mutations define novel forms of core myopathy with heart disease

  C. Chauveau;C.G. Bonnemann;C. Julien;A.L. Kho

  177
  Citations

• Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy

  Michael H. Radke;Jun Peng;Yiming Wu;Mark McNabb

  174
  Citations

• Sustained somatic gene inactivation by viral transfer of Cre recombinase

  Astrid Rohlmann;Michael Gotthardt;Thomas E. Willnow;Robert E Hammer

  165
  Citations

• Conditional Expression of Mutant M-line Titins Results in Cardiomyopathy with Altered Sarcomere Structure

  Michael Gotthardt;Michael Gotthardt;Robert E. Hammer;Norbert Hübner;Jan Monti

  162
  Citations

• Cardiac Deletion of the Coxsackievirus-Adenovirus Receptor Abolishes Coxsackievirus B3 Infection and Prevents Myocarditis In Vivo

  Yu Shi;Chen Chen;Ulrike Lisewski;Uta Wrackmeyer

  155
  Citations