Simon Beggs

Overview

Best Publications

• BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain

  Jeffrey A. M. Coull;Simon Beggs;Dominic Boudreau;Dominick Boivin

  2234
  Citations

• Different immune cells mediate mechanical pain hypersensitivity in male and female mice

  Robert E. Sorge;Josiane C.S. Mapplebeck;Sarah Rosen;Simon Beggs

  1419
  Citations

• Sublime microglia: expanding roles for the guardians of the CNS

  Michael W. Salter;Simon Beggs

  614
  Citations

• P2X4-receptor mediated synthesis and release of brain-derived neurotrophic factor in microglia is dependent on calcium and p38-mitogen-activated protein kinase activation

  Tuan Trang;Simon Beggs;Xiang Wan;Michael W. Salter

  543
  Citations

• Spinal Cord Toll-Like Receptor 4 Mediates Inflammatory and Neuropathic Hypersensitivity in Male But Not Female Mice

  Robert E. Sorge;Michael L. LaCroix-Fralish;Alexander H. Tuttle;Susana G. Sotocinal

  502
  Citations

• Morphine hyperalgesia gated through microglia-mediated disruption of neuronal Cl⁻ homeostasis.

  Francesco Ferrini;Francesco Ferrini;Tuan Trang;Theresa-Alexandra M Mattioli;Sophie Laffray

  479
  Citations

• Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity.

  Robert E. Sorge;Tuan Trang;Ruslan Dorfman;Shad B. Smith

  419
  Citations

• P2X4R+ microglia drive neuropathic pain

  Simon Beggs;Tuan Trang;Michael W Salter

  404
  Citations

• The neurobiology of pain: developmental aspects.

  Maria Fitzgerald;Simon Beggs

  375
  Citations

• Transformation of the output of spinal lamina I neurons after nerve injury and microglia stimulation underlying neuropathic pain

  A Florence Keller;Simon Beggs;Michael W Salter;Yves De Koninck

  313
  Citations

• Treatment of inflammatory and neuropathic pain by uncoupling Src from the NMDA receptor complex

  Xue Jun Liu;Jeffrey R. Gingrich;Mariana Vargas-Caballero;Yi Na Dong

  257
  Citations

• Brain-derived neurotrophic factor from microglia: a molecular substrate for neuropathic pain.

  Tuan Trang;Simon Beggs;Michael W. Salter

  243
  Citations

• Priming of adult pain responses by neonatal pain experience: maintenance by central neuroimmune activity

  Simon Beggs;Gillian Currie;Michael W. Salter;Maria Fitzgerald

  239
  Citations

• Microglial P2X4R-evoked pain hypersensitivity is sexually dimorphic in rats.

  Josiane C S Mapplebeck;Rebecca Dalgarno;YuShan Tu;Orla Moriarty

  226
  Citations

• Sex differences in pain: a tale of two immune cells.

  Josiane C. S. Mapplebeck;Simon Beggs;Michael W. Salter

  218
  Citations

• A role for HSP27 in sensory neuron survival.

  Susan E. Lewis;Richard J. Mannion;Richard J. Mannion;Fletcher A. White;Richard E. Coggeshall

  217
  Citations

• Peripheral nerve injury and TRPV1-expressing primary afferent C-fibers cause opening of the blood-brain barrier

  Simon Beggs;Xue Jun Liu;Chun Kwan;Michael W Salter

  213
  Citations

• Stereological and somatotopic analysis of the spinal microglial response to peripheral nerve injury.

  Simon Beggs;Michael W. Salter

  198
  Citations

• ATP receptors gate microglia signaling in neuropathic pain.

  Tuan Trang;Simon Beggs;Michael W. Salter

  189
  Citations

• The postnatal reorganization of primary afferent input and dorsal horn cell receptive fields in the rat spinal cord is an activity‐dependent process

  Simon Beggs;Carole Torsney;Liam J. Drew;Maria Fitzgerald

  175
  Citations