Jean-Noël Freund

Overview

Best Publications

• Wnt/β-Catenin/Tcf Signaling Induces the Transcription of Axin2, a Negative Regulator of the Signaling Pathway

  Eek-hoon Jho;Tong Zhang;Claire Domon;Choun-Ki Joo

  1967
  Citations

• SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes

  Philippe Blache;Marc van de Wetering;Isabelle Duluc;Claire Domon

  577
  Citations

• Key role of the Cdx2 homeobox gene in extracellular matrix-mediated intestinal cell differentiation.

  Olivier Lorentz;Isabelle Duluc;Adèle De Arcangelis;Patricia Simon-Assmann

  332
  Citations

• Klotho Is a Novel β-Glucuronidase Capable of Hydrolyzing Steroid β-Glucuronides

  Osamu Tohyama;Akihiro Imura;Akiko Iwano;Jean-Noël Freund

  287
  Citations

• Cdx and Hox Genes Differentially Regulate Posterior Axial Growth in Mammalian Embryos

  Teddy Young;Jennifer Elizabeth Rowland;Cesca van de Ven;Monika Bialecka

  283
  Citations

• The Cdx2 homeobox gene has a tumour suppressor function in the distal colon in addition to a homeotic role during gut development

  Bonhomme C;Duluc I;Martin E;Chawengsaksophak K

  281
  Citations

• Wnt/beta-catenin signaling regulates the expression of the homeobox gene Cdx1 in embryonic intestine

  H. Lickert;C. Domon;G. Huls;C. Wehrle

  272
  Citations

• The Cdx-1 and Cdx-2 homeobox genes in the intestine.

  Jean-Noël Freund;Claire Domon-Dell;Michèle Kedinger;Isabelle Duluc

  239
  Citations

• NADPH Oxidase 1 Modulates WNT and NOTCH1 Signaling To Control the Fate of Proliferative Progenitor Cells in the Colon

  Nicolas Coant;Sanae Ben Mkaddem;Sanae Ben Mkaddem;Eric Pedruzzi;Eric Pedruzzi;Cécile Guichard;Cécile Guichard

  212
  Citations

• PTEN and TNF-α regulation of the intestinal-specific Cdx-2 homeobox gene through a PI3K, PKB/Akt, and NF-κB-dependent pathway

  Sunghoon Kim;Claire Domon-Dell;Qingding Wang;Dai H. Chung

  178
  Citations

• Identification and characterization of human Mex-3 proteins, a novel family of evolutionarily conserved RNA-binding proteins differentially localized to processing bodies.

  Karine Buchet-Poyau;Julien Courchet;Hervé Le Hir;Bertrand Séraphin

  178
  Citations

• Functional Interference between Thyroid Hormone Receptor α (TRα) and Natural Truncated TRΔα Isoforms in the Control of Intestine Development

  Michelina Plateroti;Karine Gauthier;Claire Domon-Dell;Jean-Noël Freund

  158
  Citations

• Down-Regulation of the Homeodomain Factor Cdx2 in Colorectal Cancer by Collagen Type I An Active Role for the Tumor Environment in Malignant Tumor Progression

  Thomas Brabletz;Simone Spaderna;Jochen Kolb;Falk Hlubek

  149
  Citations

• Intestinal Epithelial-Mesenchymal Cell Interactions

  M. Kedinger;I. Duluc;C. Fritsch;O. Lorentz

  146
  Citations

• The intestine-specific homeobox gene Cdx2 decreases mobility and antagonizes dissemination of colon cancer cells.

  Gross I;Duluc I;Benameur T;Calon A

  135
  Citations

• Down-regulation of the Tumor Suppressor PTEN by the Tumor Necrosis Factor-α/Nuclear Factor-κB (NF-κB)-inducing Kinase/NF-κB Pathway Is Linked to a Default IκB-α Autoregulatory Loop *

  Sunghoon Kim;Claire Domon-Dell;Junghee Kang;Dai H. Chung

  133
  Citations

• The rudimentary gene of Drosophila melanogaster encodes four enzymic functions

  J.N. Freund;B.P. Jarry

  132
  Citations

• Fetal endoderm primarily holds the temporal and positional information required for mammalian intestinal development

  I Duluc;J N Freund;C Leberquier;M Kedinger

  132
  Citations

• Involvement of T3Rα- and β-receptor subtypes in mediation of T3 functions during postnatal murine intestinal development

  Michelina Plateroti;Olivier Chassande;Alexandre Fraichard;Karine Gauthier

  126
  Citations

• Bile Acids Induce Ectopic Expression of Intestinal Guanylyl Cyclase C Through Nuclear Factor-κB and Cdx2 in Human Esophageal Cells

  Philip R. Debruyne;Philip R. Debruyne;Matthew Witek;Li Gong;Ruth Birbe

  121
  Citations