World's Best Scientists 2026 revealed!
Jean-Noël Freund

Jean-Noël Freund

D-Index & Metrics

Biology and Biochemistry

D-Index
50
Citations
10650
World Ranking
17540
National Ranking
757

Jean-Noël Freund publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Jean-Noël Freund sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 181 publications — 42nd percentile

42% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Jean-Noël Freund D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Jean-Noël Freund sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 50 D-Index — 11th percentile

11% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Jean-Noël Freund is affiliated with Inserm in France and has contributed to research primarily in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their scholarly work encompasses various subfields including Molecular Biology, Genetics, Pathology and Forensic Medicine, Cell Biology, and Oncology.

The scientist has explored a range of topics, with a focus on digestive system and related health, renal and related cancers, genetic factors in colorectal cancer, zebrafish biomedical research applications, congenital heart defects research, cancer cells and metastasis, and epigenetics and DNA methylation.

Freund's recent papers include:

  • "Actomyosin, vimentin and LINC complex pull on osteosarcoma nuclei to deform on micropillar topography" (2020) published in Biomaterials
  • "Concurrent CDX2 cis-deregulation and UBTF::ATXN7L3 fusion define a novel high-risk subtype of B-cell ALL" (2022) published in Blood
  • "The Appendix Orchestrates T-Cell Mediated Immunosurveillance in Colitis-Associated Cancer" (2022) published in Cellular and Molecular Gastroenterology and Hepatology
  • "CD32 captures committed haemogenic endothelial cells during human embryonic development" (2024) published in Nature Cell Biology
  • "CDX2 controls genes involved in the metabolism of 5-fluorouracil and is associated with reduced efficacy of chemotherapy in colorectal cancer" (2022) published in Biomedicine & Pharmacotherapy

Freund frequently collaborates with several researchers, including Manuela Tavian, Isabelle Duluc, Claire Domon-Dell, Elisabeth Martin, and Isabelle Groß.

The study results have been disseminated through multiple publication venues, with repeated contributions to Blood, Biomedicine & Pharmacotherapy, Molecular Oncology, bioRxiv (Cold Spring Harbor Laboratory), and Research Square.

Best Publications

  • Wnt/β-Catenin/Tcf Signaling Induces the Transcription of Axin2, a Negative Regulator of the Signaling Pathway

    Eek-hoon Jho;Tong Zhang;Claire Domon;Choun-Ki Joo

  • SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes

    Philippe Blache;Marc van de Wetering;Isabelle Duluc;Claire Domon

  • Key role of the Cdx2 homeobox gene in extracellular matrix-mediated intestinal cell differentiation.

    Olivier Lorentz;Isabelle Duluc;Adèle De Arcangelis;Patricia Simon-Assmann

  • Klotho Is a Novel β-Glucuronidase Capable of Hydrolyzing Steroid β-Glucuronides

    Osamu Tohyama;Akihiro Imura;Akiko Iwano;Jean-Noël Freund

  • Cdx and Hox Genes Differentially Regulate Posterior Axial Growth in Mammalian Embryos

    Teddy Young;Jennifer Elizabeth Rowland;Cesca van de Ven;Monika Bialecka

  • The Cdx2 homeobox gene has a tumour suppressor function in the distal colon in addition to a homeotic role during gut development

    Bonhomme C;Duluc I;Martin E;Chawengsaksophak K

  • Wnt/beta-catenin signaling regulates the expression of the homeobox gene Cdx1 in embryonic intestine

    H. Lickert;C. Domon;G. Huls;C. Wehrle

  • The Cdx-1 and Cdx-2 homeobox genes in the intestine.

    Jean-Noël Freund;Claire Domon-Dell;Michèle Kedinger;Isabelle Duluc

  • NADPH Oxidase 1 Modulates WNT and NOTCH1 Signaling To Control the Fate of Proliferative Progenitor Cells in the Colon

    Nicolas Coant;Sanae Ben Mkaddem;Sanae Ben Mkaddem;Eric Pedruzzi;Eric Pedruzzi;Cécile Guichard;Cécile Guichard

  • PTEN and TNF-α regulation of the intestinal-specific Cdx-2 homeobox gene through a PI3K, PKB/Akt, and NF-κB-dependent pathway

    Sunghoon Kim;Claire Domon-Dell;Qingding Wang;Dai H. Chung

  • Identification and characterization of human Mex-3 proteins, a novel family of evolutionarily conserved RNA-binding proteins differentially localized to processing bodies.

    Karine Buchet-Poyau;Julien Courchet;Hervé Le Hir;Bertrand Séraphin

  • Functional Interference between Thyroid Hormone Receptor α (TRα) and Natural Truncated TRΔα Isoforms in the Control of Intestine Development

    Michelina Plateroti;Karine Gauthier;Claire Domon-Dell;Jean-Noël Freund

  • Down-Regulation of the Homeodomain Factor Cdx2 in Colorectal Cancer by Collagen Type I An Active Role for the Tumor Environment in Malignant Tumor Progression

    Thomas Brabletz;Simone Spaderna;Jochen Kolb;Falk Hlubek

  • Intestinal Epithelial-Mesenchymal Cell Interactions

    M. Kedinger;I. Duluc;C. Fritsch;O. Lorentz

  • The intestine-specific homeobox gene Cdx2 decreases mobility and antagonizes dissemination of colon cancer cells.

    Gross I;Duluc I;Benameur T;Calon A

  • Down-regulation of the Tumor Suppressor PTEN by the Tumor Necrosis Factor-α/Nuclear Factor-κB (NF-κB)-inducing Kinase/NF-κB Pathway Is Linked to a Default IκB-α Autoregulatory Loop *

    Sunghoon Kim;Claire Domon-Dell;Junghee Kang;Dai H. Chung

  • The rudimentary gene of Drosophila melanogaster encodes four enzymic functions

    J.N. Freund;B.P. Jarry

  • Fetal endoderm primarily holds the temporal and positional information required for mammalian intestinal development

    I Duluc;J N Freund;C Leberquier;M Kedinger

  • Involvement of T3Rα- and β-receptor subtypes in mediation of T3 functions during postnatal murine intestinal development

    Michelina Plateroti;Olivier Chassande;Alexandre Fraichard;Karine Gauthier

  • Bile Acids Induce Ectopic Expression of Intestinal Guanylyl Cyclase C Through Nuclear Factor-κB and Cdx2 in Human Esophageal Cells

    Philip R. Debruyne;Philip R. Debruyne;Matthew Witek;Li Gong;Ruth Birbe

Frequent Co-Authors

Michèle Kedinger
Michèle Kedinger University of Strasbourg
Philippe Lavalle
Philippe Lavalle University of Strasbourg
Jean-Claude Voegel
Jean-Claude Voegel University of Strasbourg
Patricia M. Davidson
Patricia M. Davidson Johns Hopkins University
Thomas Brabletz
Thomas Brabletz University of Erlangen-Nuremberg
Sung-Hoon Kim
Sung-Hoon Kim Yonsei University
Jürgen Rühe
Jürgen Rühe University of Freiburg
Patricia Simon-Assmann
Patricia Simon-Assmann Grenoble Alpes University
Yoram Bouhnik
Yoram Bouhnik Beaujon Hospital

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