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Medicine

D-Index
87
Citations
30287
World Ranking
13570
National Ranking
557

Overview

David R. Mack is affiliated with the University of Ottawa in Canada. Their research spans a broad range of topics primarily within medicine and biochemistry, genetics, and molecular biology. The main focus areas of their work include inflammatory bowel disease, microscopic colitis, and gut microbiota and health, with additional interests in adolescent and pediatric healthcare, Helicobacter pylori-related gastroenterology, childhood cancer survivors' quality of life, and eosinophilic esophagitis.

Their research extends into several subfields including genetics, epidemiology, molecular biology, surgery, and speech and hearing. These domains reflect a multidisciplinary approach to gastrointestinal and related health sciences.

David R. Mack has published extensively, with frequent contributions appearing in venues such as:

  • Gastroenterology
  • Journal of the Canadian Association of Gastroenterology
  • Journal of Crohn's and Colitis
  • Inflammatory Bowel Diseases
  • Journal of Pediatric Gastroenterology and Nutrition

Recent papers by David R. Mack include:

  • "Butyrate's role in human health and the current progress towards its clinical application to treat gastrointestinal disease," 2022, Clinical Nutrition
  • "Novel Fecal Biomarkers That Precede Clinical Diagnosis of Ulcerative Colitis," 2020, Gastroenterology
  • "Altered Gut Microbiome Composition and Function Are Associated With Gut Barrier Dysfunction in Healthy Relatives of Patients With Crohn's Disease," 2022, Gastroenterology
  • "Mediterranean-Like Dietary Pattern Associations With Gut Microbiome Composition and Subclinical Gastrointestinal Inflammation," 2022, Gastroenterology
  • "Revealing proteome-level functional redundancy in the human gut microbiome using ultra-deep metaproteomics," 2023, Nature Communications

Their frequent collaborators include Anne M. Griffiths, Kevan Jacobson, Anthony Otley, Hien Q. Huynh, and Williams Turpin. These partnerships have contributed to a significant body of co-authored research in related medical fields.

Best Publications

  • The Treatment-Naive Microbiome in New-Onset Crohn’s Disease

    Dirk Gevers;Subra Kugathasan;Lee A. Denson;Yoshiki Vázquez-Baeza

  • Probiotics inhibit enteropathogenic E. coli adherence in vitro by inducing intestinal mucin gene expression.

    David R. Mack;Sonia Michail;Shu Wei;Laura McDougall

  • Development, Validation, and Evaluation of a Pediatric Ulcerative Colitis Activity Index: A Prospective Multicenter Study

    Dan Turner;Anthony R. Otley;David Mack;Jeffrey Hyams

  • The prevalence of celiac disease in average-risk and at-risk Western European populations: a systematic review.

    Catherine Dubé;Alaa Rostom;Richmond Sy;Ann Cranney

  • Extracellular MUC3 mucin secretion follows adherence of Lactobacillus strains to intestinal epithelial cells in vitro.

    D R Mack;S Ahrne;L Hyde;S Wei

  • The diagnostic accuracy of serologic tests for celiac disease: A systematic review

    Alaa Rostom;Catherine Dubé;Ann Cranney;Navaaz Saloojee

  • Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study

    Subra Kugathasan;Lee A. Denson;Thomas D. Walters;Mi Ok Kim

  • Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature

    Yael Haberman;Timothy L. Tickle;Phillip J. Dexheimer;Mi-Ok Kim

  • Increasing incidence of paediatric inflammatory bowel disease in Ontario, Canada: evidence from health administrative data

    Eric Ian Benchimol;Astrid Guttmann;Anne M Griffiths;Linda Rabeneck

  • Altered intestinal microbiota–host mitochondria crosstalk in new onset Crohn’s disease

    Walid Mottawea;Cheng-Kang Chiang;Marcus Mühlbauer;Amanda E. Starr

  • Imbalances in Dietary Consumption of Fatty Acids, Vegetables, and Fruits Are Associated With Risk for Crohn's Disease in Children

    Devendra K Amre;Savio D'Souza;Kenneth Morgan;Gillian Seidman

  • Evaluation of the pediatric crohn disease activity index: a prospective multicenter experience.

    Jeffrey Hyams;James Markowitz;Anthony Otley;Joel Rosh

  • Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response

    Yael Haberman;Yael Haberman;Rebekah Karns;Phillip J. Dexheimer;Melanie Schirmer

  • Appraisal of the pediatric ulcerative colitis activity index (PUCAI)

    Dan Turner;Dan Turner;Jeffrey Hyams;James Markowitz;Trudy Lerer

  • Trends in Epidemiology of Pediatric Inflammatory Bowel Disease in Canada: Distributed Network Analysis of Multiple Population-Based Provincial Health Administrative Databases

    Eric I Benchimol;Charles N Bernstein;Alain Bitton;Matthew W Carroll

  • Biliary Atresia: The Canadian Experience

    Richard A. Schreiber;Collin C. Barker;Eve A. Roberts;Steven R. Martin

  • Increased effectiveness of early therapy with anti-tumor necrosis factor-α vs an immunomodulator in children with Crohn's disease.

    Thomas D. Walters;Mi Ok Kim;Lee A. Denson;Anne M. Griffiths

  • Alterations in the gut microbiome of children with severe ulcerative colitis.

    Sonia Michail;Matthew Durbin;Dan Turner;Anne M. Griffiths

  • Mathematical weighting of the pediatric Crohn's disease activity index (PCDAI) and comparison with its other short versions

    Dan Turner;Anne M. Griffiths;Thomas D. Walters;Tong Seah

  • Severe pediatric ulcerative colitis: a prospective multicenter study of outcomes and predictors of response.

    Dan Turner;David Mack;Neal Leleiko;Thomas D. Walters

Frequent Co-Authors

Anne M. Griffiths
Anne M. Griffiths University of Toronto
Jeffrey S. Hyams
Jeffrey S. Hyams University of Connecticut
Subra Kugathasan
Subra Kugathasan Emory University
Lee A. Denson
Lee A. Denson Cincinnati Children's Hospital Medical Center
Robert N. Baldassano
Robert N. Baldassano Children's Hospital of Philadelphia
Jonathan P. Evans
Jonathan P. Evans University of Western Australia
Ernest G. Seidman
Ernest G. Seidman McGill University
Dan Turner
Dan Turner Hebrew University of Jerusalem
Alain Stintzi
Alain Stintzi University of Ottawa
Marla Dubinsky
Marla Dubinsky Icahn School of Medicine at Mount Sinai

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