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Biology and Biochemistry

D-Index
135
Citations
91750
World Ranking
346
National Ranking
232

Overview

Kenneth M. Murphy is affiliated with Washington University in St. Louis in the United States. Their research primarily focuses on the fields of Immunology and Microbiology, with additional contributions in Medicine. Within these areas, their subfields of study include Immunology, Oncology, Molecular Biology, Infectious Diseases, and Genetics.

Their work addresses a range of topics related to immune function, with notable focus areas including Immunotherapy and Immune Responses, T-cell and B-cell Immunology, Immune Cell Function and Interaction, Cancer Immunotherapy and Biomarkers, Immune cells in cancer, RNA Interference and Gene Delivery, and CAR-T cell therapy research.

Kenneth M. Murphy has published extensively in several scientific venues. The most frequent outlets for their work are:

  • The Journal of Immunology
  • Immunity
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Experimental Medicine
  • Proceedings of the National Academy of Sciences

Frequent co-authors collaborating with Kenneth M. Murphy include:

  • Tiantian Liu
  • Sun Kyung Kim
  • Theresa L. Murphy
  • Feiya Ou
  • Renee Wu

Recent publications by Kenneth M. Murphy feature peer-reviewed research articles on topics related to dendritic cell biology, immune surveillance, and cancer immunology. Some of the recent papers include:

  • cDC1 prime and are licensed by CD4+ T cells to induce anti-tumour immunity, 2020, Nature
  • Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer, 2020, Cancer Cell
  • Genetic models of human and mouse dendritic cell development and function, 2020, Nature Reviews Immunology
  • Dendritic cells in cancer immunology, 2021, Cellular and Molecular Immunology
  • Tumor-associated macrophages expressing the transcription factor IRF8 promote T cell exhaustion in cancer, 2022, Immunity

Best Publications

  • Interleukin 17–producing CD4 + effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

    Laurie E Harrington;Robin D Hatton;Paul R Mangan;Henrietta Turner

  • Functional diversity of helper T lymphocytes.

    Abul K. Abbas;Kenneth M. Murphy;Alan Sher

  • Janeway's immunobiology

    Kenneth Murphy;Casey Weaver

  • Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages

    Chyi Song Hsieh;Steven E. Macatonia;Catherine S. Tripp;Stanley F. Wolf

  • The lineage decisions of helper T cells

    Kenneth M. Murphy;Steven L. Reiner

  • Batf3 Deficiency Reveals a Critical Role for CD8α+ Dendritic Cells in Cytotoxic T Cell Immunity

    Kai Hildner;Brian T. Edelson;Whitney E. Purtha;Mark Diamond

  • Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo

    Kenneth M. Murphy;Amy B. Heimberger;Dennis Y. Loh

  • Th17: an effector CD4 T cell lineage with regulatory T cell ties.

    Casey T. Weaver;Laurie E. Harrington;Paul R. Mangan;Maya Gavrieli

  • Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells.

    S. E. Macatonia;N. A. Hosken;M. Litton;P. Vieira

  • Dendritic cell regulation of TH1-TH2 development.

    Muriel Moser;Kenneth M. Murphy

  • T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells

    Maryam Afkarian;John R. Sedy;Jianfei Yang;Nils G. Jacobson

  • Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells.

    Susanne J. Szabo;Anand S. Dighe;Ueli Gubler;Kenneth M. Murphy

  • Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8α+ dendritic cells

    Mercedes B. Fuertes;Aalok K. Kacha;Justin Kline;Seng Ryong Woo

  • A Validated Regulatory Network for Th17 Cell Specification

    Maria Ciofani;Aviv Madar;Aviv Madar;Carolina Galan;MacLean Sellars

  • Type I interferon is selectively required by dendritic cells for immune rejection of tumors

    Mark S. Diamond;Michelle Kinder;Hirokazu Matsushita;Mona Mashayekhi

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Mübeccel Akdis

  • BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1.

    Norihiko Watanabe;Norihiko Watanabe;Maya Gavrieli;John R Sedy;Jianfei Yang;Jianfei Yang

  • Inhibition of Th1 Development Mediated by GATA-3 through an IL-4-Independent Mechanism

    Wenjun Ouyang;Sheila H Ranganath;Kathryn Weindel;Deepta Bhattacharya

  • Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system.

    Chyi-Song Hsieh;Amy B. Heimberger;Jennifer S. Gold;Anne O'Garra

  • The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha beta-transgenic model.

    Nancy A. Hosken;Kazuko Shibuya;Andrew W. Heath;Kenneth M. Murphy

Frequent Co-Authors

Theresa L. Murphy
Theresa L. Murphy Washington University in St. Louis
Ansuman T. Satpathy
Ansuman T. Satpathy Stanford University
Robert D. Schreiber
Robert D. Schreiber Washington University in St. Louis
Casey T. Weaver
Casey T. Weaver University of Alabama at Birmingham
Chyi-Song Hsieh
Chyi-Song Hsieh Washington University in St. Louis
Wenjun Ouyang
Wenjun Ouyang Amgen (United States)
L. David Sibley
L. David Sibley Washington University in St. Louis
Anne O'Garra
Anne O'Garra The Francis Crick Institute
Dennis Y. Loh
Dennis Y. Loh Washington University in St. Louis
Michael S. Diamond
Michael S. Diamond Washington University in St. Louis

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