John Maher

Overview

Best Publications

• Human T-lymphocyte cytotoxicity and proliferation directed by a single chimeric TCRzeta /CD28 receptor.

  John Maher;Renier J Brentjens;Gertrude Gunset;Isabelle Rivière

  1259
  Citations

• Dual Targeting of ErbB2 and MUC1 in Breast Cancer Using Chimeric Antigen Receptors Engineered to Provide Complementary Signaling

  Scott Wilkie;May C. I. van Schalkwyk;Steve Hobbs;David M. Davies

  509
  Citations

• Retargeting of human T cells to tumor-associated MUC1: the evolution of a chimeric antigen receptor.

  Scott Wilkie;Gianfranco Picco;Julie Foster;David M. Davies

  401
  Citations

• The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9

  Richard Beatson;Virginia Tajadura-Ortega;Daniela Yordanova Achkova;Gianfranco Picco

  376
  Citations

• T cell response to SARS-CoV-2 infection in humans: A systematic review.

  Nathan Post;Danielle Eddy;Catherine Huntley;May C. I. van Schalkwyk

  355
  Citations

• Expression of a Chimeric Antigen Receptor Specific for Donor HLA Class I Enhances the Potency of Human Regulatory T Cells in Preventing Human Skin Transplant Rejection.

  Dominic A. Boardman;Christina Philippeos;Gilbert O. Fruhwirth;Mohammad A. A. Ibrahim

  319
  Citations

• Nucleic acids encoding chimeric T cell receptors

  Michel Sadelain;Renier Brentjens;John Maher

  283
  Citations

• Selective Expansion of Chimeric Antigen Receptor-targeted T-cells with Potent Effector Function using Interleukin-4

  Scott Wilkie;Sophie E. Burbridge;Laura Chiapero-Stanke;Ana C.P. Pereira

  212
  Citations

• Strategies to Address Chimeric Antigen Receptor Tonic Signaling.

  Adam Ajina;John Maher

  187
  Citations

• CAR T-Cells Targeting the Integrin αvβ6 and Co-Expressing the Chemokine Receptor CXCR2 Demonstrate Enhanced Homing and Efficacy against Several Solid Malignancies

  Lynsey M. Whilding;Leena Halim;Benjamin Draper;Ana C. Parente-Pereira

  176
  Citations

• Ovarian cancer immunotherapy using PD-L1 siRNA targeted delivery from folic acid-functionalized polyethylenimine: strategies to enhance T cell killing.

  Pei Yun Teo;Chuan Yang;Lynsey M. Whilding;Lynsey M. Whilding;Ana C. Parente-Pereira

  176
  Citations

• CAR T Cells Targeting the Tumor MUC1 Glycoprotein Reduce Triple-Negative Breast Cancer Growth

  Ru Zhou;Mahboubeh Yazdanifar;Lopamudra Das Roy;Lynsey M. Whilding

  150
  Citations

• Targeting cytotoxic T lymphocytes for cancer immunotherapy

  John Maher;E T Davies

  143
  Citations

• Trafficking of CAR-engineered human T cells following regional or systemic adoptive transfer in SCID beige mice.

  Ana Caterina Parente-Pereira;Jerome Burnet;David Ellison;Julie Foster

  136
  Citations

• Design of a phase I clinical trial to evaluate intratumoral delivery of ErbB-targeted chimeric antigen receptor T-cells in locally advanced or recurrent head and neck cancer.

  May C I van Schalkwyk;Sophie E Papa;Jean-Pierre Jeannon;Teresa Guerrero Urbano

  134
  Citations

• Enhanced Anti-lymphoma Activity of CAR19-iNKT Cells Underpinned by Dual CD19 and CD1d Targeting

  Antonia Rotolo;Valentina S. Caputo;Monika Holubova;Monika Holubova;Nicoleta Baxan

  132
  Citations

• Prospects for combined use of oncolytic viruses and CAR T-cells.

  Adam Ajina;John Maher;John Maher;John Maher

  131
  Citations

• Preclinical In Vivo Modeling of Cytokine Release Syndrome Induced by ErbB-Retargeted Human T Cells: Identifying a Window of Therapeutic Opportunity?

  Sjoukje J. C. van der Stegen;David M. Davies;Scott Wilkie;Julie Foster

  125
  Citations

• Antibody response to SARS-CoV-2 infection in humans: a systematic review

  Nathan Post;Danielle Eddy;Catherine Huntley;May C. I. van Schalkwyk

  123
  Citations

• Flexible Targeting of ErbB Dimers That Drive Tumorigenesis by Using Genetically Engineered T Cells

  David M Davies;Julie Foster;Sjoukje J C Van Der Stegen;Ana C Parente-Pereira

  120
  Citations