What is he best known for?
The fields of study he is best known for:
- Immune system
- Cancer
- Antibody
Hinrich Abken spends much of his time researching T cell, Antigen, Chimeric antigen receptor, Molecular biology and Cytotoxic T cell.
His T cell study introduces a deeper knowledge of Immunology.
His research in Antigen intersects with topics in Receptor, Cancer research and CD30.
Hinrich Abken is investigating Chimeric antigen receptor as part of his inquiry into Immunotherapy and Immune system.
Hinrich Abken has researched Molecular biology in several fields, including Major histocompatibility complex, Transfection and T-cell receptor.
Epitope is closely connected to CD8 in his research, which is encompassed under the umbrella topic of Cell biology.
His most cited work include:
- IL-12 release by engineered T cells expressing chimeric antigen receptors can effectively Muster an antigen-independent macrophage response on tumor cells that have shut down tumor antigen expression. (265 citations)
- Tumor-specific T cell activation by recombinant immunoreceptors: CD3 zeta signaling and CD28 costimulation are simultaneously required for efficient IL-2 secretion and can be integrated into one combined CD28/CD3 zeta signaling receptor molecule. (239 citations)
- TRUCKs: the fourth generation of CARs. (225 citations)
What are the main themes of his work throughout his whole career to date?
Hinrich Abken mostly deals with Immunology, T cell, Antigen, Chimeric antigen receptor and Cancer research.
His Cytotoxic T cell research extends to Immunology, which is thematically connected.
He focuses mostly in the field of T cell, narrowing it down to topics relating to Cell biology and, in certain cases, Secretion.
His Antigen research is multidisciplinary, incorporating perspectives in Receptor, Molecular biology, Adoptive cell transfer, T-cell receptor and Antibody.
His studies in Chimeric antigen receptor integrate themes in fields like Cancer cell, Leukemia, Cell therapy and Virology.
His Cancer research research incorporates themes from Natural killer cell, Car t cells and B cell.
He most often published in these fields:
- Immunology (38.67%)
- T cell (37.78%)
- Antigen (34.22%)
What were the highlights of his more recent work (between 2017-2021)?
- Chimeric antigen receptor (34.67%)
- Cancer research (28.44%)
- Cell biology (27.56%)
In recent papers he was focusing on the following fields of study:
His primary areas of investigation include Chimeric antigen receptor, Cancer research, Cell biology, Cell therapy and T cell.
His biological study spans a wide range of topics, including CD28, Cell, Leukemia and Cytokine.
The concepts of his Cancer research study are interwoven with issues in IL-2 receptor, Immune system, B cell and Epitope, Antigen.
His IL-2 receptor study combines topics from a wide range of disciplines, such as Natural killer T cell, Interleukin 21 and Antigen-presenting cell.
His work carried out in the field of Cell biology brings together such families of science as Luciferase and Bacteria.
His T cell research is under the purview of Immunology.
Between 2017 and 2021, his most popular works were:
- Nanobody Based Dual Specific CARs (50 citations)
- CAR T Cells in Trials: Recent Achievements and Challenges that Remain in the Production of Modified T Cells for Clinical Applications (45 citations)
- Intra-tumoral production of IL18, but not IL12, by TCR-engineered T cells is non-toxic and counteracts immune evasion of solid tumors. (42 citations)
In his most recent research, the most cited papers focused on:
- Immune system
- Cancer
- Antibody
Chimeric antigen receptor, Cancer research, Cell therapy, T cell and Immunotherapy are his primary areas of study.
His Chimeric antigen receptor research incorporates elements of Leukemia, Cytokine, CD19 and Cell biology.
Hinrich Abken has included themes like B cell, Interleukin 12 and Antigen in his Cancer research study.
Hinrich Abken works mostly in the field of Antigen, limiting it down to topics relating to Car t cells and, in certain cases, Cell, as a part of the same area of interest.
His Cell therapy study combines topics in areas such as Transforming growth factor, Psychological repression and Immune system.
His T cell study is concerned with the larger field of Immunology.
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