Maria R. Parkhurst

Overview

Best Publications

• Cancer Immunotherapy Based on Mutation-Specific CD4+ T Cells in a Patient with Epithelial Cancer

  Eric Tran;Simon Turcotte;Alena Gros;Paul F. Robbins

  2306
  Citations

• Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma

  Steven A. Rosenberg;James C. Yang;Douglas J. Schwartzentruber;Patrick Hwu

  2270
  Citations

• T Cells Targeting Carcinoembryonic Antigen Can Mediate Regression of Metastatic Colorectal Cancer but Induce Severe Transient Colitis

  Maria R. Parkhurst;James C. Yang;Russell C. Langan;Mark E. Dudley

  1217
  Citations

• Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patients

  Alena Gros;Maria R Parkhurst;Eric Tran;Anna Pasetto

  894
  Citations

• Improved induction of melanoma-reactive CTL with peptides from the melanoma antigen gp100 modified at HLA-A*0201-binding residues.

  Maria R. Parkhurst;Michael L. Salgaller;Scott Southwood;Paul F. Robbins

  738
  Citations

• GP100/PMEL 17 IS A MURINE TUMOR REJECTION ANTIGEN : INDUCTION OF SELF -REACTIVE, TUMORICIDAL T CELLS USING HIGH-AFFINITY, ALTERED PEPTIDE LIGAND

  Willem W. Overwijk;Allan Tsung;Kari R. Irvine;Maria R. Parkhurst

  612
  Citations

• Adoptive Transfer of Autologous Natural Killer Cells Leads to High Levels of Circulating Natural Killer Cells but Does Not Mediate Tumor Regression

  Maria R. Parkhurst;John P. Riley;Mark E. Dudley;Steven A. Rosenberg

  585
  Citations

• Molecular signatures of antitumor neoantigen-reactive T cells from metastatic human cancers

  Unknown

  567
  Citations

• Stem-like CD8 T cells mediate response of adoptive cell immunotherapy against human cancer

  Sri Krishna;Frank J. Lowery;Amy R. Copeland;Erol Bahadiroglu

  489
  Citations

• Isolation of neoantigen-specific T cells from tumor and peripheral lymphocytes

  Cyrille J. Cohen;Cyrille J. Cohen;Jared J. Gartner;Miryam Horovitz-Fried;Katerina Shamalov

  411
  Citations

• Utilization of an alternative open reading frame of a normal gene in generating a novel human cancer antigen.

  Rong Fu Wang;Maria R. Parkhurst;Yutaka Kawakami;Paul F. Robbins

  397
  Citations

• Melanoma-specific CD4 + T Cells Recognize Nonmutated HLA-DR-restricted Tyrosinase Epitopes

  Suzanne L. Topalian;Monica I. Gonzales;Maria Parkhurst;Yong F. Li

  393
  Citations

• mRNA vaccine–induced neoantigen-specific T cell immunity in patients with gastrointestinal cancer

  Gal Cafri;Jared J Gartner;Tal Zaks;Kristen Hopson

  381
  Citations

• Identification of a Shared HLA-A*0201-restricted T-Cell Epitope from the Melanoma Antigen Tyrosinase-related Protein 2 (TRP2)

  Maria R. Parkhurst;Ellen B. Fitzgerald;Scott Southwood;Alessandro Sette

  296
  Citations

• Unique Neoantigens Arise from Somatic Mutations in Patients with Gastrointestinal Cancers

  Maria R. Parkhurst;Paul F Robbins;Eric Tran;Todd D. Prickett

  277
  Citations

• Neoantigen screening identifies broad TP53 mutant immunogenicity in patients with epithelial cancers

  Parisa Malekzadeh;Anna Pasetto;Paul F. Robbins;Maria R. Parkhurst

  256
  Citations

• A phenotypic signature that identifies neoantigen-reactive T cells in fresh human lung cancers.

  Unknown

  240
  Citations

• Enhanced detection of neoantigen-reactive T cells targeting unique and shared oncogenes for personalized cancer immunotherapy.

  Rami Yossef;Eric Tran;Drew C. Deniger;Alena Gros

  223
  Citations

• A TCR Targeting the HLA-A*0201–Restricted Epitope of MAGE-A3 Recognizes Multiple Epitopes of the MAGE-A Antigen Superfamily in Several Types of Cancer

  Nachimuthu Chinnasamy;Jennifer A. Wargo;Zhiya Yu;Mahadev Rao

  215
  Citations

• Tumor- and Neoantigen-Reactive T-cell Receptors Can Be Identified Based on Their Frequency in Fresh Tumor

  Anna Pasetto;Alena Gros;Paul F. Robbins;Drew C. Deniger

  204
  Citations

• Isolation of T-Cell Receptors Specifically Reactive with Mutated Tumor-Associated Antigens from Tumor-Infiltrating Lymphocytes Based on CD137 Expression

  Maria R. Parkhurst;Alena Gros;Anna Pasetto;Todd D. Prickett

  176
  Citations

• Characterization of Genetically Modified T-Cell Receptors that Recognize the CEA:691-699 Peptide in the Context of HLA-A2.1 on Human Colorectal Cancer Cells

  Maria R. Parkhurst;Jayne S Joo;John P. Riley;Zhiya Yu

  176
  Citations