1988 - Fellow of Alfred P. Sloan Foundation
His scientific interests lie mostly in DNA, Pyrimidine dimer, Molecular biology, DNA polymerase and Stereochemistry. His research in DNA intersects with topics in Combinatorial chemistry and Nucleic acid. His Pyrimidine dimer study combines topics in areas such as Thymine, Mutagenesis and Photochemistry.
His studies in Molecular biology integrate themes in fields like Cell, Internalization, Biochemistry, Xeroderma pigmentosum and Chinese hamster ovary cell. His studies deal with areas such as Polymerase, DNA replication and DNA synthesis as well as DNA polymerase. His Stereochemistry research includes themes of Cofactor, Base pair, Dimer, Cyclobutane and Photolyase.
John-Stephen Taylor spends much of his time researching DNA, Pyrimidine dimer, Stereochemistry, Biochemistry and Molecular biology. His DNA study typically links adjacent topics like Dimer. The concepts of his Pyrimidine dimer study are interwoven with issues in Thymine, Mutagenesis and Photochemistry.
The study incorporates disciplines such as Deamination, Enzyme, Solid-phase synthesis, Cyclobutane and Photolyase in addition to Stereochemistry. His work in the fields of Nucleic acid, Peptide and Binding site overlaps with other areas such as Heat shock factor. His work carried out in the field of Molecular biology brings together such families of science as Base excision repair, Xeroderma pigmentosum, Biophysics, DNA synthesis and DNA replication.
John-Stephen Taylor focuses on DNA, Pyrimidine dimer, Molecular biology, Biochemistry and Stereochemistry. John-Stephen Taylor interconnects Cancer, Skin cancer, Cancer research, Biophysics and Transfection in the investigation of issues within DNA. The Pyrimidine dimer study combines topics in areas such as Photochemistry, Nucleotide excision repair, Nucleosome, Cyclobutane and Flap structure-specific endonuclease 1.
His study in Molecular biology is interdisciplinary in nature, drawing from both Nucleic acid, Small interfering RNA, DNA polymerase, Histone and Peptide. His work deals with themes such as Base excision repair, DNA repair, DNA polymerase II and Polymerase, which intersect with DNA polymerase. His work in Biochemistry tackles topics such as Cationic polymerization which are related to areas like Polymer and Nanoparticle.
The scientist’s investigation covers issues in Biochemistry, Nucleic acid, DNA, Peptide and DNA polymerase. His Nucleic acid research incorporates themes from Organic chemistry, Nanotechnology and Biodistribution. Specifically, his work in DNA is concerned with the study of Pyrimidine dimer.
His Pyrimidine dimer research is multidisciplinary, incorporating elements of Lifetime risk, Melanoma and Skin cancer. John-Stephen Taylor has included themes like Base excision repair, Flap structure-specific endonuclease 1, Molecular biology and Nucleotide excision repair in his DNA polymerase study. The various areas that John-Stephen Taylor examines in his Molecular biology study include DNA clamp, Polymerase, DNA polymerase mu, DNA polymerase I and DNA repair.
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Roles of E. coli DNA polymerases IV and V in lesion-targeted and untargeted SOS mutagenesis.
Mengjia Tang;Phuong Pham;Xuan Shen;John-Stephen Taylor.
Nature (2000)
Error-free and error-prone lesion bypass by human DNA polymerase κ in vitro
Yanbin Zhang;Fenghua Yuan;Xiaohua Wu;Mu Wang;Mu Wang.
Nucleic Acids Research (2000)
UNRAVELING THE MOLECULAR PATHWAY FROM SUNLIGHT TO SKIN CANCER
John Stephen Taylor.
Accounts of Chemical Research (1994)
Comparative analysis of binding of human damaged DNA-binding protein (XPE) and Escherichia coli damage recognition protein (UvrA) to the major ultraviolet photoproducts: T[c,s]T, T[t,s]T, T[6-4]T, and T[Dewar]T.
J T Reardon;A F Nichols;S Keeney;C A Smith.
Journal of Biological Chemistry (1993)
Crystal structure of a DNA decamer containing a cis-syn thymine dimer
HaJeung Park;Kaijiang Zhang;Yingjie Ren;Sourena Nadji.
Proceedings of the National Academy of Sciences of the United States of America (2002)
Error-prone lesion bypass by human DNA polymerase η
Yanbin Zhang;Fenghua Yuan;Xiaohua Wu;Olga Rechkoblit.
Nucleic Acids Research (2000)
Shape effects of nanoparticles conjugated with cell-penetrating peptides (HIV Tat PTD) on CHO cell uptake.
Ke Zhang;Huafeng Fang;Zhiyun Chen;John-Stephen A. Taylor.
Bioconjugate Chemistry (2008)
Cytochrome c Biogenesis: Mechanisms for Covalent Modifications and Trafficking of Heme and for Heme-Iron Redox Control
Robert G. Kranz;Cynthia Richard-Fogal;John-Stephen Taylor;Elaine R. Frawley.
Microbiology and Molecular Biology Reviews (2009)
Characterization of (6-4) photoproduct DNA photolyase.
Sang Tae Kim;Khushbeer Malhotra;Colin A. Smith;John Stephen Taylor.
Journal of Biological Chemistry (1994)
Reaction Mechanism of (6-4) Photolyase
Xiaodong Zhao;Jianquan Liu;David S. Hsu;Shaying Zhao.
Journal of Biological Chemistry (1997)
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