World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
115
Citations
50602
World Ranking
307
National Ranking
185

Research.com Recognitions

  • 2015 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Gerd P. Pfeifer is affiliated with the Van Andel Institute in the United States. Their research primarily falls within the field of Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology. The broader scope of their work spans several subfields including Cancer Research, Hematology, Genetics, and Pediatrics, Perinatology and Child Health.

The scientist has contributed to a range of topics related to molecular and cancer biology. Key topics include:

  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • Cancer-related gene regulation
  • Genomics and Chromatin Dynamics
  • CRISPR and Genetic Engineering
  • DNA Repair Mechanisms
  • Cancer Genomics and Diagnostics

Gerd P. Pfeifer's notable recent papers include:

  • "Mechanisms of UV-induced mutations and skin cancer", 2020, Genome Instability & Disease
  • "Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia", 2022, Cancer Discovery
  • "UVA Radiation, DNA Damage, and Melanoma", 2022, ACS Omega
  • "The chromosomal protein SMCHD1 regulates DNA methylation and the 2c-like state of embryonic stem cells by antagonizing TET proteins", 2021, Science Advances
  • "Concordance of hydrogen peroxide-induced 8-oxo-guanine patterns with two cancer mutation signatures of upper GI tract tumors", 2022, Science Advances

The venues where Gerd P. Pfeifer frequently publishes reveal their research interests and collaborations. These include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Epigenomics
  • Genome Instability & Disease
  • Science Advances
  • International Journal of Molecular Sciences

Collaboration is a significant aspect of their research process. Frequent co-authors associated with their work include:

  • Seung-Gi Jin
  • Jennifer Johnson
  • Zhijun Huang
  • Wei Cui
  • Xue Qing David Wang

Gerd P. Pfeifer was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2015.

Best Publications

  • Preferential Formation of Benzo[a]pyrene Adducts at Lung Cancer Mutational Hotspots in P53

    Mikhail F. Denissenko;Annie Pao;Moon-shong Tang;Gerd P. Pfeifer

  • Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3.

    Reinhard Dammann;Chun Li;Jung-Hoon Yoon;Philip L. Chin

  • Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers

    Gerd P Pfeifer;Mikhail F Denissenko;Magali Olivier;Natalia Tretyakova

  • The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes

    Tian-Peng Gu;Fan Guo;Hui Yang;Hai-Ping Wu;Hai-Ping Wu

  • Mutations induced by ultraviolet light

    Gerd P. Pfeifer;Young-Hyun You;Ahmad Besaratinia

  • Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine

    Khursheed Iqbal;Seung-Gi Jin;Gerd P. Pfeifer;Piroska E. Szabó

  • Aging and DNA methylation.

    Marc Jung;Gerd P Pfeifer

  • UV wavelength-dependent DNA damage and human non-melanoma and melanoma skin cancer

    Gerd P. Pfeifer;Ahmad Besaratinia

  • Genomic sequencing and methylation analysis by ligation mediated PCR

    Gerd P. Pfeifer;Sabine D. Steigerwald;Paul R. Mueller;Barbara Wold

  • Patterns of p53 G-->T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke.

    Pierre Hainaut;Gerd P. Pfeifer

  • Examination of the specificity of DNA methylation profiling techniques towards 5-methylcytosine and 5-hydroxymethylcytosine

    Seung-Gi Jin;Swati Kadam;Gerd P. Pfeifer

  • 5-Hydroxymethylcytosine Is Strongly Depleted in Human Cancers but Its Levels Do Not Correlate with IDH1 Mutations

    Seung-Gi Jin;Yong Jiang;Runxiang Qiu;Tibor A. Rauch

  • Dynamics of 5-Hydroxymethylcytosine and Chromatin Marks in Mammalian Neurogenesis

    Maria A. Hahn;Runxiang Qiu;Xiwei Wu;Arthur X. Li

  • Global methylation profiling of lymphoblastoid cell lines reveals epigenetic contributions to autism spectrum disorders and a novel autism candidate gene, RORA, whose protein product is reduced in autistic brain

    AnhThu Nguyen;Tibor A. Rauch;Gerd P. Pfeifer;Valerie W. Hu

  • X-chromosome inactivation and cell memory

    Arthur D. Riggs;Gerd P. Pfeifer

  • Genomic mapping of 5-hydroxymethylcytosine in the human brain

    Seung-Gi Jin;Xiwei Wu;Arthur X. Li;Gerd P. Pfeifer

  • Cytosine methylation determines hot spots of DNA damage in the human P53 gene.

    Mikhail F. Denissenko;James X. Chen;Moon-shong Tang;Gerd P. Pfeifer

  • Slow repair of pyrimidine dimers at p53 mutation hotspots in skin cancer

    S. Tornaletti;G.P. Pfeifer

  • MIRA-Assisted Microarray Analysis, a New Technology for the Determination of DNA Methylation Patterns, Identifies Frequent Methylation of Homeodomain-Containing Genes in Lung Cancer Cells

    Tibor Rauch;Hongwei Li;Xiwei Wu;Gerd P. Pfeifer

  • A human B cell methylome at 100−base pair resolution

    Tibor A. Rauch;Xiwei Wu;Xueyan Zhong;Arthur D. Riggs

Frequent Co-Authors

Xiwei Wu
Xiwei Wu City Of Hope National Medical Center
Arthur D. Riggs
Arthur D. Riggs City Of Hope National Medical Center
Pierre Hainaut
Pierre Hainaut Grenoble Alpes University
Jeffrey R. Mann
Jeffrey R. Mann Monash University
Binghui Shen
Binghui Shen City Of Hope National Medical Center
Xingzhi Xu
Xingzhi Xu Shenzhen University
Farida Latif
Farida Latif University of Birmingham
Yinsheng Wang
Yinsheng Wang University of California, Riverside
Yuan Chen
Yuan Chen University of Sydney
Volker M. Arlt
Volker M. Arlt King's College London

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