World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
50
Citations
13541
World Ranking
2538
National Ranking
1250

Overview

David Grunwald is affiliated with the University of Utah in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, reflecting a multidisciplinary approach to biological and medical sciences.

Their work explores a range of scientific topics including:

  • Osteoarthritis Treatment and Mechanisms
  • Genomics and Chromatin Dynamics
  • Epigenetics and DNA Methylation
  • Hedgehog Signaling Pathway Studies
  • Genomic Variations and Chromosomal Abnormalities
  • Bone Metabolism and Diseases
  • Bone and Dental Protein Studies

Grunwald's frequent co-authors include:

  • Michael J. Jurynec
  • Matthew Honeggar
  • Nikolas H. Kazmers
  • K. Novak
  • Kazuyuki Hoshijima

The scientist's work has been published in several venues, with repeated publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Osteoarthritis and Cartilage
  • Genome Research
  • PLoS Biology
  • Annals of Human Genetics

Notable recent papers by David Grunwald include:

  • "Chromatin architecture transitions from zebrafish sperm through early embryogenesis" (2021), Genome Research
  • "Smoothened transduces Hedgehog signals via activity-dependent sequestration of PKA catalytic subunits" (2021), PLoS Biology
  • "A role for the MEGF6 gene in predisposition to osteoporosis" (2020), Annals of Human Genetics
  • "NOD/RIPK2 signalling pathway contributes to osteoarthritis susceptibility" (2022), Annals of the Rheumatic Diseases
  • "Crosstalk Between Retinoic Acid and Sex-Related Genes Controls Germ Cell Fate and Gametogenesis in Medaka" (2021), Frontiers in Cell and Developmental Biology

Grunwald's research efforts demonstrate a consistent engagement with molecular biology, genetics, and medical research topics. Their publications reveal contributions to understanding disease mechanisms related to osteoarthritis and bone metabolism, chromatin structure dynamics, signaling pathways, and genetic predispositions to various conditions.

The scientist maintains a focus on integrating genetic and molecular insights with disease mechanisms, particularly within the context of bone and cartilage diseases, as indicated by their work appearing in specialized rheumatology and osteoarthritis journals.

Best Publications

  • SLC24A5, a Putative Cation Exchanger, Affects Pigmentation in Zebrafish and Humans

    Rebecca L. Lamason;Manzoor Ali P.K. Mohideen;Manzoor Ali P.K. Mohideen;Jason R. Mest;Andrew C. Wong;Andrew C. Wong

  • Charon phages: safer derivatives of bacteriophage lambda for DNA cloning

    Frederick R. Blattner;Bill G. Williams;Ann E. Blechl;Katherine Denniston-Thompson

  • Headwaters of the zebrafish — emergence of a new model vertebrate

    David Jonah Grunwald;Judith S. Eisen

  • Developmental regulation of zebrafish MyoD in wild-type, no tail and spadetail embryos

    E.S. Weinberg;M.L. Allende;C.S. Kelly;A. Abdelhamid

  • Measuring image resolution in optical nanoscopy.

    Robert P J Nieuwenhuizen;Keith A Lidke;Mark Bates;Daniela Leyton Puig

  • Lithium perturbation and goosecoid expression identify a dorsal specification pathway in the pregastrula zebrafish

    Scott E. Stachel;David J. Grunwald;Paul Z. Myers

  • Simple Methods for Generating and Detecting Locus- Specific Mutations Induced with TALENs in the Zebrafish Genome

    Timothy J. Dahlem;Kazuyuki Hoshijima;Michael J. Jurynec;Derrick Gunther

  • Multiplexed labeling of genomic loci with dCas9 and engineered sgRNAs using CRISPRainbow

    Hanhui Ma;Li-Chun Tu;Ardalan Naseri;Maximiliaan Huisman

  • In vivo imaging of labelled endogenous β-actin mRNA during nucleocytoplasmic transport

    David Grünwald;Robert H. Singer

  • The zebrafish gene cloche acts upstream of a flk-1 homologue to regulate endothelial cell differentiation

    Wayne Liao;Brent W. Bisgrove;Holly Sawyer;Barbara Hug

  • Nuclear transport of single molecules: dwell times at the nuclear pore complex.

    Ulrich Kubitscheck;David Jonah Grunwald;Andreas Hoekstra;Daniel Rohleder

  • Precise Editing of the Zebrafish Genome Made Simple and Efficient

    Kazuyuki Hoshijima;Michael J. Jurynec;David Jonah Grunwald

  • Highly Efficient CRISPR-Cas9-Based Methods for Generating Deletion Mutations and F0 Embryos that Lack Gene Function in Zebrafish

    Kazuyuki Hoshijima;Michael J. Jurynec;Dana Klatt Shaw;Ashley M. Jacobi

  • RNA Processing and Export

    Sami Hocine;Robert H. Singer;David Grünwald

  • Nuclear export dynamics of RNA–protein complexes

    David Grünwald;Robert H. Singer;Michael Rout

  • TIF1γ Controls Erythroid Cell Fate by Regulating Transcription Elongation

    Xiaoying Bai;Jonghwan Kim;Jonghwan Kim;Zhongan Yang;Michael J. Jurynec

  • Selenoprotein N is required for ryanodine receptor calcium release channel activity in human and zebrafish muscle.

    Michael J. Jurynec;Ruohong Xia;John J. Mackrill;Derrick Gunther

  • A neural degeneration mutation that spares primary neurons in the zebrafish

    David J. Grunwald;Charles B. Kimmel;Monte Westerfield;Charline Walker

  • Efficient identification of TALEN‐mediated genome modifications using heteroduplex mobility assays

    Satoshi Ota;Yu Hisano;Michiko Muraki;Kazuyuki Hoshijima

  • CRISPR-Cas9 nuclear dynamics and target recognition in living cells

    Hanhui Ma;Li-Chun Tu;Ardalan Naseri;Maximiliaan Huisman

Frequent Co-Authors

Robert H. Singer
Robert H. Singer Albert Einstein College of Medicine
Thoru Pederson
Thoru Pederson University of Massachusetts Chan Medical School
Lisa A. Cannon-Albright
Lisa A. Cannon-Albright University of Utah
Nevan J. Krogan
Nevan J. Krogan University of California, San Francisco
Karsten Weis
Karsten Weis ETH Zurich
David W. Raible
David W. Raible University of Washington
Judith S. Eisen
Judith S. Eisen University of Oregon
Phillip D. Zamore
Phillip D. Zamore University of Massachusetts Chan Medical School
Mark Leppert
Mark Leppert University of Utah
Leonard I. Zon
Leonard I. Zon Harvard University

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