2002 - Hellman Fellow
Karsten Weis mainly investigates Cell biology, Ran, Nuclear pore, Biochemistry and Importin. His research in Cell biology is mostly focused on Nuclear transport. His research integrates issues of Microtubule and Mitosis in his study of Ran.
While the research belongs to areas of Mitosis, Karsten Weis spends his time largely on the problem of Multipolar spindles, intersecting his research to questions surrounding Chromatin. His studies examine the connections between Nuclear pore and genetics, as well as such issues in Nucleoporin, with regards to Nucleocytoplasmic Transport and RNA transport. As part of one scientific family, Karsten Weis deals mainly with the area of Importin, narrowing it down to issues related to the Karyopherin, and often Nuclear export signal.
His primary areas of study are Cell biology, Nuclear pore, Ran, Nuclear transport and Biochemistry. His studies deal with areas such as RNA, Messenger RNA and Saccharomyces cerevisiae as well as Cell biology. His Nuclear pore research is multidisciplinary, relying on both Nucleoporin, Nucleocytoplasmic Transport, Biophysics, RNA transport and Cell nucleus.
His Nucleocytoplasmic Transport research focuses on Karyopherins and how it connects with Beta Karyopherins. His Ran research includes themes of Spindle apparatus, Spindle pole body, GTPase, Microtubule and Importin. His studies in Importin integrate themes in fields like Karyopherin and Permeability.
Karsten Weis mainly focuses on Cell biology, RNA, Biophysics, Organelle and Messenger RNA. His Yeast research extends to Cell biology, which is thematically connected. His study focuses on the intersection of Biophysics and fields such as Biomolecule with connections in the field of Compartmentalization, Macromolecule, Sequence, Coacervate and Sequence motif.
His Organelle research includes elements of Flux and Microfluidics. Karsten Weis focuses mostly in the field of Messenger RNA, narrowing it down to matters related to Cytoplasm and, in some cases, Nucleus and Binding site. His Nuclear pore study necessitates a more in-depth grasp of Genetics.
Cell biology, Biophysics, Cytoplasm, Organelle and DEAD box are his primary areas of study. Karsten Weis combines Cell biology and Elongation in his studies. His work carried out in the field of Cytoplasm brings together such families of science as ATPase, In vitro, Messenger RNA, Activator and In vivo.
His work deals with themes such as Transcription and Transcriptome, Gene expression, which intersect with Messenger RNA. His Organelle research incorporates elements of ATP hydrolysis, Ribonucleoprotein, Nucleolus, Cytoskeleton and Artificial cell. His DEAD box study incorporates themes from Flux and RNA transport.
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Exportin 1 (Crm1p) Is an Essential Nuclear Export Factor
Katrin Stade;Charleen S. Ford;Christine Guthrie;Karsten Weis.
Cell (1997)
Regulating Access to the Genome: Nucleocytoplasmic Transport throughout the Cell Cycle
Karsten Weis.
Cell (2003)
Retinoic acid regulates aberrant nuclear localization of PML-RARα in acute promyelocytic leukemia cells
Karsten Weis;Sophie Rambaud;Catherine Lavau;Joop Jansen.
Cell (1994)
Structure of importin-beta bound to the IBB domain of importin-alpha.
Gino Cingolani;Carlo Petosa;Karsten Weis;Christoph W. Müller.
Nature (1999)
Visualization of a Ran-GTP Gradient in Interphase and Mitotic Xenopus Egg Extracts
Petr Kalab;Karsten Weis;Rebecca Heald.
Science (2002)
Importin β Is a Mitotic Target of the Small GTPase Ran in Spindle Assembly
Maxence V Nachury;Thomas J Maresca;Wendy C Salmon;Clare M Waterman-Storer.
Cell (2001)
Identification of hSRP1α as a Functional Receptor for Nuclear Localization Sequences
Karsten Weis;Iain W. Mattaj;Angus I. Lamond.
Science (1995)
Analysis of a RanGTP-regulated gradient in mitotic somatic cells
Petr Kaláb;Arnd Pralle;Ehud Y. Isacoff;Rebecca Heald.
Nature (2006)
Importins and exportins: how to get in and out of the nucleus
Karsten Weis.
Trends in Biochemical Sciences (1998)
Importin-beta-like nuclear transport receptors
Anne-Christine Ström;Karsten Weis.
Genome Biology (2001)
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