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Douglas E. Brenneman

Douglas E. Brenneman

D-Index & Metrics

Neuroscience

D-Index
70
Citations
14613
World Ranking
2552
National Ranking
1205

Overview

Douglas E. Brenneman is affiliated with Kannalife Sciences in the United States and has contributed to research primarily in medicine, immunology, and microbiology. Their work addresses multiple subfields, including immunology, pharmacology, physiology, molecular biology, and cellular and molecular neuroscience. The research topics covered include toxin mechanisms and immunotoxins, cannabis and cannabinoid research, pain mechanisms and treatments, cancer treatment and pharmacology, sphingolipid metabolism and signaling, neuroscience and neuropharmacology research, and pharmacological receptor mechanisms and effects.

Their publication record features articles in various scientific venues, with a notable frequency of publications in the Journal of Molecular Neuroscience. Other venues include Research Square, the British Journal of Pharmacology, the Journal of Pharmacology and Experimental Therapeutics, and UNC Libraries.

Recent papers authored or co-authored by Douglas E. Brenneman include:

  • Behavioural and pharmacological effects of cannabidiol (CBD) and the cannabidiol analogue KLS-13019 in mouse models of pain and reinforcement, 2021, British Journal of Pharmacology
  • Anti-Inflammatory Properties of KLS-13019: a Novel GPR55 Antagonist for Dorsal Root Ganglion and Hippocampal Cultures, 2022, Journal of Molecular Neuroscience
  • KLS-13019, a Novel Structural Analogue of Cannabidiol and GPR55 Receptor Antagonist, Prevents and Reverses Chemotherapy-Induced Peripheral Neuropathy in Rats, 2024, Journal of Pharmacology and Experimental Therapeutics
  • Knockdown siRNA Targeting GPR55 Reveals Significant Differences Between the Anti-inflammatory Actions of KLS-13019 and Cannabidiol, 2024, Journal of Molecular Neuroscience
  • Effect of Fatty Acyl Composition for Lysophosphatidylinositol on Neuroinflammatory Responses in Primary Neuronal Cultures, 2025, Journal of Molecular Neuroscience

Douglas E. Brenneman frequently collaborates with several researchers including William A. Kinney, Sara Jane Ward, Mark E. McDonnell, Michael Ippolito, and Pingei Zhao. This network of co-authors reflects ongoing partnerships in the areas of neuropharmacology and cellular neuroscience as well as pain and inflammatory research.

Best Publications

  • Neuronal cell killing by the envelope protein of HIV and its prevention by vasoactive intestinal peptide.

    Douglas E. Brenneman;Gary L. Westbrook;Sandra P. Fitzgerald;David L. Ennist

  • Complete sequence of a novel protein containing a femtomolar-activity-dependent neuroprotective peptide.

    Merav Bassan;Rachel Zamostiano;Ariane Davidson;Albert Pinhasov

  • Vasoactive intestinal peptide and electrical activity influence neuronal survival.

    Douglas E. Brenneman;Lee E. Eiden

  • Growth factor function of vasoactive intestinal peptide in whole cultured mouse embryos

    Pierre Gressens;Joanna M. Hill;Illana Gozes;Mati Fridkin

  • A femtomolar-acting neuroprotective peptide.

    D E Brenneman;I Gozes

  • VIP: molecular biology and neurobiological function.

    Illana Gozes;Douglas E. Brenneman

  • Nonneuronal cells mediate neurotrophic action of vasoactive intestinal peptide.

    D E Brenneman;E A Neale;G A Foster;S W d'Autremont

  • Cloning and characterization of the human activity-dependent neuroprotective protein.

    Rachel Zamostiano;Albert Pinhasov;Edgar Gelber;Ruth A. Steingart

  • PACAP Functions as a Neurotrophic Factor

    A. Arimura;A. Somogyvari;C. Weill;R. C. Fiore

  • Cytokine Regulation of Neuronal Survival

    Douglas E. Brenneman;Marianne Schultzberg;Tamas Bartfai;Illana Gozes

  • A Peptide Derived from Activity-Dependent Neuroprotective Protein (ADNP) Ameliorates Injury Response in Closed Head Injury in Mice

    Liana Beni-Adani;Illana Gozes;Yoram Cohen;Yaniv Assaf

  • Activity-dependent neuroprotective protein: a novel gene essential for brain formation.

    Albert Pinhasov;Shmuel Mandel;Arkady Torchinsky;Eliezer Giladi

  • Vasoactive intestinal peptide: A neurotrophic releasing agent and an astroglial mitogen

    Douglas E. Brenneman;T. Nicol;D. Warren;L. M. Bowers

  • A glia-derived signal regulating neuronal differentiation.

    Olivier Blondel;Carlos Collin;William J. McCarran;Shiaoping Zhu

  • Vasoactive Intestinal Peptide and Pituitary Adenylate Cyclase-activating Polypeptide Inhibit Tumor Necrosis Factor α Transcriptional Activation by Regulating Nuclear Factor-kB and cAMP Response Element-binding Protein/c-Jun

    Mario Delgado;Ernesto J. Munoz-Elias;Yanqing Kan;Illana Gozes

  • Neuroprotective strategy for Alzheimer disease: intranasal administration of a fatty neuropeptide.

    I Gozes;A Bardea;A Reshef;R Zamostiano

  • Learning impairment following intracerebral administration of the HIV envelope protein gp120 or a VIP antagonist.

    John R. Glowa;Leigh V. Panlilio;Douglas E. Brenneman;Illana Gozes;Illana Gozes

  • Vasoactive intestinal peptide prevents excitotoxic cell death in the murine developing brain.

    Pierre Gressens;S Marret;Jonathan Hill;D E Brenneman

  • Activity-Dependent Neurotrophic Factor: Intranasal Administration of Femtomolar-Acting Peptides Improve Performance in a Water Maze

    Illana Gozes;Eliezer Giladi;Albert Pinhasov;Amos Bardea

  • Activity-Dependent Neurotrophic Factor: Structure-Activity Relationships of Femtomolar-Acting Peptides

    Douglas E. Brenneman;Janet Hauser;Elaine Neale;Sara Rubinraut

  • Prevention of fetal demise and growth restriction in a mouse model of fetal alcohol syndrome.

    Catherine Y. Spong;Daniel T. Abebe;Illana Gozes;Douglas E. Brenneman

Frequent Co-Authors

Phillip G. Nelson
Phillip G. Nelson National Institutes of Health
Lee E. Eiden
Lee E. Eiden National Institutes of Health
Denes V. Agoston
Denes V. Agoston Uniformed Services University of the Health Sciences
Carlos R. Plata-Salamán
Carlos R. Plata-Salamán Independent Scientist / Consultant, US
John C. Mulley
John C. Mulley Bangor University
James A. Waschek
James A. Waschek University of California, Los Angeles
Eliezer Masliah
Eliezer Masliah National Institutes of Health
Tamas Bartfai
Tamas Bartfai Stockholm University
Leigh V. Panlilio
Leigh V. Panlilio National Institute on Drug Abuse
Gary L. Westbrook
Gary L. Westbrook Oregon Health & Science University

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