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D-Index & Metrics

Biology and Biochemistry

D-Index
78
Citations
20986
World Ranking
4555
National Ranking
2216

Overview

Mark S. Kindy is affiliated with the University of South Florida in the United States. Their research spans several interconnected fields within biomedical science, focusing particularly on medicine, neuroscience, and biochemistry, genetics, and molecular biology. The subfields prominently featured in their work include physiology, molecular biology, neurology, cellular and molecular neuroscience, and endocrinology, diabetes, and metabolism.

The scientific topics addressed by Kindy encompass a range of areas related to neurological and metabolic diseases. These topics include:

  • Alzheimer's disease research and treatments
  • Diet and metabolism studies
  • Neurological disease mechanisms and treatments
  • Metabolism, diabetes, and cancer
  • Pancreatic function and diabetes
  • Amyloidosis: Diagnosis, treatment, outcomes
  • Diet, metabolism, and disease

Kindy has contributed to publications in various peer-reviewed academic venues. Frequent publication venues include:

  • Stroke
  • Nutrients
  • Circulation
  • Pharmacological Reviews
  • Journal of Alzheimer s Disease

Their recent papers demonstrate a focus on neurological disorders and metabolic conditions with examples such as:

  • Cathepsin B Gene Knockout Improves Behavioral Deficits and Reduces Pathology in Models of Neurologic Disorders (2022, Pharmacological Reviews)
  • Cathepsin B Deficiency Improves Memory Deficits and Reduces Amyloid-β in hAβPP Mouse Models Representing the Major Sporadic Alzheimer's Disease Condition (2023, Journal of Alzheimer s Disease)
  • Exogenous Ketone Supplements Improved Motor Performance in Preclinical Rodent Models (2020, Nutrients)
  • Cytochrome P450 CYP2E1 Suppression Ameliorates Cerebral Ischemia Reperfusion Injury (2021, Antioxidants)
  • Roles of hepatic atypical protein kinase C hyperactivity and hyperinsulinemia in insulin-resistant forms of obesity and type 2 diabetes mellitus (2021, MedComm)

Kindy collaborates frequently with other researchers. The most common coauthors include:

  • Saeid Taheri
  • Jin Yu
  • David M. Diamond
  • Hong Zhu
  • Mini P. Sajan

Best Publications

  • RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain.

    Rashid Deane;Shi Du Yan;Ram Kumar Submamaryan;Barbara LaRue

  • Mitochondrial Manganese Superoxide Dismutase Prevents Neural Apoptosis and Reduces Ischemic Brain Injury: Suppression of Peroxynitrite Production, Lipid Peroxidation, and Mitochondrial Dysfunction

    Jeffrey N. Keller;Mark S. Kindy;Fredrick W. Holtsberg;Daret K. St. Clair

  • Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors

    Annadora J. Bruce;Warren Boling;Mark S. Kindy;Jacques Peschon

  • Estrogen receptor α, not β, is a critical link in estradiol-mediated protection against brain injury

    Dena B. Dubal;Hong Zhu;Jin Yu;Shane W. Rau

  • GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism

    Yazhou Li;Tracy Ann Perry;Mark S. Kindy;Brandon K. Harvey

  • Inhibition of Alzheimer's Amyloidosis by Peptides That Prevent β-Sheet Conformation

    Claudio Soto;Mark S. Kindy;Marc Baumann;Blas Frangione

  • Neprilysin Gene Transfer Reduces Human Amyloid Pathology in Transgenic Mice

    Robert A. Marr;Edward Rockenstein;Atish Mukherjee;Mark S. Kindy

  • Receptor-dependent cell stress and amyloid accumulation in systemic amyloidosis

    Shi Du Yan;Huaijie Zhu;Aiping Zhu;Adam Golabek

  • RAGE potentiates Aβ-induced perturbation of neuronal function in transgenic mice

    Ottavio Arancio;Hui Ping Zhang;Xi Chen;Chang Lin

  • High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice.

    Lakshmi Thirumangalakudi;Annamalai Prakasam;Ran Zhang;Heather Bimonte-Nelson

  • Lack of the p50 subunit of nuclear factor-κb increases the vulnerability of hippocampal neurons to excitotoxic injury

    ZaiFang Yu;Daohong Zhou;Annadora J. Bruce-Keller;Mark S. Kindy

  • Regulation of c-myc transcription and mRNA abundance by serum growth factors and cell contact

    M Dean;R A Levine;W Ran;M S Kindy

  • Ischemic and Excitotoxic Brain Injury is Enhanced in Mice Lacking the p55 Tumor Necrosis Factor Receptor

    Devin S. Gary;Annadora J. Bruce-Keller;Mark S. Kindy;Mark P. Mattson

  • Inhibitors of Cathepsin B Improve Memory and Reduce β-Amyloid in Transgenic Alzheimer Disease Mice Expressing the Wild-type, but Not the Swedish Mutant, β-Secretase Site of the Amyloid Precursor Protein

    Vivian Y. H. Hook;Mark Kindy;Gregory Hook

  • Serum amyloid A (SAA): influence on HDL-mediated cellular cholesterol efflux.

    C L Banka;T Yuan;M C de Beer;M Kindy

  • Altered brain activation in cognitively intact individuals at high risk for Alzheimer’s disease

    C.D. Smith;A.H. Andersen;R.J. Kryscio;F.A. Schmitt

  • Presenilin-1 Mutation Increases Neuronal Vulnerability to Focal Ischemia In Vivo and to Hypoxia and Glucose Deprivation in Cell Culture: Involvement of Perturbed Calcium Homeostasis

    Mark P. Mattson;Haiyan Zhu;Jin Yu;Jin Yu;Mark S. Kindy;Mark S. Kindy

  • Heparin prevents vascular smooth muscle cell progression through the G1 phase of the cell cycle.

    C F Reilly;M S Kindy;K E Brown;R D Rosenberg

  • Transcranial laser therapy attenuates amyloid-β peptide neuropathology in amyloid-β protein precursor transgenic mice.

    Luis De Taboada;Jin Yu;Salim El-Amouri;Sebastiano Gattoni-Celli;Sebastiano Gattoni-Celli

  • Neprilysin: an enzyme candidate to slow the progression of Alzheimer's disease.

    Salim S. El-Amouri;Hong Zhu;Jin Yu;Robert Marr

Frequent Co-Authors

Vivian Hook
Vivian Hook University of California, San Diego
Robert J. Dempsey
Robert J. Dempsey University of Wisconsin–Madison
Stephen Tomlinson
Stephen Tomlinson Medical University of South Carolina
Mark P. Mattson
Mark P. Mattson Johns Hopkins University
Nancy R. Webb
Nancy R. Webb University of Kentucky
Kumar Sambamurti
Kumar Sambamurti Medical University of South Carolina
William R. Markesbery
William R. Markesbery University of Kentucky
Jeffrey N. Keller
Jeffrey N. Keller Pennington Biomedical Research Center
Phyllis M. Wise
Phyllis M. Wise University of Washington
Narayan R. Bhat
Narayan R. Bhat Medical University of South Carolina

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