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Biology and Biochemistry

D-Index
59
Citations
11172
World Ranking
12671
National Ranking
322

Overview

Henk L. Dekker is affiliated with the University of Amsterdam in the Netherlands. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology, Oncology, and Cancer Research.

The main topics covered in Dekker's work include Colorectal Cancer Treatments and Studies, PI3K/AKT/mTOR signaling in cancer, Chronic Lymphocytic Leukemia Research, as well as Marine Biology and Ecology Research. Their interdisciplinary expertise also extends to Aquatic Invertebrate Ecology and Behavior, Marine Bivalve and Aquaculture Studies, and Advanced Proteomics Techniques and Applications.

Dekker has published articles in several journals, with frequent publications appearing in:

  • Cancers
  • Cancer Medicine
  • European Journal of Medicinal Chemistry
  • International Journal of Molecular Sciences
  • Zootaxa

Some recent papers authored by or involving Dekker include:

  • Imidazo[2,1-b] [1,3,4]thiadiazoles with antiproliferative activity against primary and gemcitabine-resistant pancreatic cancer cells (2020) in European Journal of Medicinal Chemistry
  • Kinase Inhibitor Treatment of Patients with Advanced Cancer Results in High Tumor Drug Concentrations and in Specific Alterations of the Tumor Phosphoproteome (2020) in Cancers
  • Effects of Cancer Presence and Therapy on the Platelet Proteome (2021) in International Journal of Molecular Sciences
  • High-Dose Intermittent Treatment with the Multikinase Inhibitor Sunitinib Leads to High Intra-Tumor Drug Exposure in Patients with Advanced Solid Tumors (2022) in Cancers
  • A specific microRNA profile as predictive biomarker for systemic treatment in patients with metastatic colorectal cancer (2020) in Cancer Medicine

Dekker has collaborated with several frequent co-authors during their career, including:

  • Henk M.W. Verheul
  • Mariëtte Labots
  • Sander R. Piersma
  • Thang V. Pham
  • Connie R. Jiménez

Best Publications

  • Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein

    G J Zaman;J Lankelma;O van Tellingen;J Beijnen

  • A small, cysteine-rich protein secreted by Fusarium oxysporum during colonization of xylem vessels is required for I-3-mediated resistance in tomato

    Martijn Rep;H. Charlotte Van Der Does;Michiel Meijer;Ringo Van Wijk

  • The mixed xylem sap proteome of Fusarium oxysporum-infected tomato plants.

    Petra M. Houterman;Dave Speijer;Henk L. Dekker;Chris G. De Koster

  • The novel Cladosporium fulvum lysin motif effector Ecp6 is a virulence factor with orthologues in other fungal species

    Melvin D Bolton;H Peter van Esse;Jack H Vossen;Ronnie de Jonge

  • Lysosomal sequestration of sunitinib: a novel mechanism of drug resistance

    Kristy J. Gotink;Henk J. Broxterman;Mariette Labots;Richard R. de Haas

  • Proteomic Analysis of Candida albicans Cell Walls Reveals Covalently Bound Carbohydrate-Active Enzymes and Adhesins

    Piet W. J. de Groot;Albert D. de Boer;Jeff Cunningham;Henk L. Dekker

  • Doxorubicin Gradients in Human Breast Cancer

    J. Lankelma;H. Dekker;R. Fernandez Luque;S. Luykx

  • Comprehensive Proteomic Analysis of Saccharomyces cerevisiae Cell Walls IDENTIFICATION OF PROTEINS COVALENTLY ATTACHED VIA GLYCOSYLPHOSPHATIDYLINOSITOL REMNANTS OR MILD ALKALI-SENSITIVE LINKAGES

    Qing Yuan Yin;Piet W.J. de Groot;Henk L. Dekker;Luitzen de Jong

  • Mass spectrometric identification of isoforms of PR proteins in xylem sap of fungus-infected tomato

    Martijn Rep;Henk L. Dekker;Jack H. Vossen;Albert D. de Boer

  • The Cell Wall of the Human Pathogen Candida glabrata: Differential Incorporation of Novel Adhesin-Like Wall Proteins

    Piet W. J. de Groot;Eefje A. Kraneveld;Qing Yuan Yin;Henk L. Dekker

  • Isolation and identification of phosphatidic acid targets from plants

    Christa Testerink;Henk L. Dekker;Ze-Yi Lim;Melloney K. Johns

  • From phosphatases to vanadium peroxidases: a similar architecture of the active site.

    Wieger Hemrika;Rokus Renirie;Henk L. Dekker;Phil Barnett

  • Cortisol is transported by the multidrug resistance gene product P-glycoprotein

    C. K. van Kalken;H. J. Broxterman;H. M. Pinedo;N. Feller

  • Heat shock protein 90 and its co-chaperone protein phosphatase 5 interact with distinct regions of the tomato I-2 disease resistance protein

    Sergio De La Fuente Bentem van;Jack H. Vossen;Klaas Jan de Vries;Saskia van Wees

  • H2O2 Production in Species of the Lactobacillus acidophilus Group: a Central Role for a Novel NADH-Dependent Flavin Reductase

    Rosanne Hertzberger;Jos Arents;Henk L. Dekker;R. David Pridmore

  • Identification of novel candidate phosphatidic acid-binding proteins involved in the salt-stress response of Arabidopsis thaliana roots.

    Fionn McLoughlin;Steven A. Arisz;Henk L. Dekker;Gertjan Kramer

  • Enantioselective Sulfoxidation Catalyzed by Vanadium Haloperoxidases.

    Hilda B. ten Brink;Antonin Tuynman;Henk L. Dekker;Wieger Hemrika

  • Supramolecular organization and dual function of the IsiA chlorophyll-binding protein in cyanobacteria.

    Nataliya Yeremenko;Roman Kouril;Janne A Ihalainen;Sandrine D'Haene

  • Effects of fluconazole on the secretome, the wall proteome, and wall integrity of the clinical fungus Candida albicans

    Alice G. Sorgo;Clemens J. Heilmann;Henk L. Dekker;Martijn Bekker

  • Time-series resolution of gradual nitrogen starvation and its impact on photosynthesis in the cyanobacterium Synechocystis PCC 6803.

    Vladimir Krasikov;Eneas Aguirre von Wobeser;Henk L. Dekker;Jef Huisman

Frequent Co-Authors

Chris G. de Koster
Chris G. de Koster University of Amsterdam
Henk M.W. Verheul
Henk M.W. Verheul Radboud University
Jan Lankelma
Jan Lankelma Vrije Universiteit Amsterdam
Ron Wever
Ron Wever University of Amsterdam
Godefridus J. Peters
Godefridus J. Peters Gdańsk Medical University
Connie R. Jimenez
Connie R. Jimenez Vrije Universiteit Amsterdam
Sander R. Piersma
Sander R. Piersma VU University Medical Center
Frans M. Klis
Frans M. Klis University of Amsterdam
Klaas J. Hellingwerf
Klaas J. Hellingwerf University of Amsterdam
Hans V. Westerhoff
Hans V. Westerhoff Vrije Universiteit Amsterdam

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