Member of the European Molecular Biology Organization (EMBO)
Her main research concerns Cell biology, Endosome, Vesicle, Golgi apparatus and Immunoelectron microscopy. Transport protein is the focus of her Cell biology research. Judith Klumperman interconnects Cell membrane, Clathrin, Mannose 6-phosphate, Endocytic cycle and Syntaxin in the investigation of issues within Endosome.
Her work is dedicated to discovering how Vesicle, COPI are connected with COPII and other disciplines. The Golgi apparatus study combines topics in areas such as Immunogold labelling and Membrane. She has researched Autophagy in several fields, including Secretion, PI3K/AKT/mTOR pathway and Programmed cell death.
Judith Klumperman mainly focuses on Cell biology, Endosome, Golgi apparatus, Endoplasmic reticulum and Biochemistry. Her Cell biology study combines topics in areas such as Vesicle, Immunoelectron microscopy, Endocytosis and Membrane protein. Her Endocytosis study integrates concerns from other disciplines, such as Autophagy, Internalization and Organelle.
The various areas that Judith Klumperman examines in her Endosome study include Syntaxin, Cell membrane, Clathrin, Endocytic cycle and Effector. Judith Klumperman combines subjects such as Molecular biology and Epidermal growth factor with her study of Clathrin. Her studies deal with areas such as Brefeldin A and Protein targeting as well as Endocytic cycle.
Her primary areas of investigation include Cell biology, Endosome, Endoplasmic reticulum, Endocytic cycle and Autophagy. Her Cell biology research incorporates elements of Biogenesis and Neurodegeneration. Her Endosome study incorporates themes from GTPase, Endocytosis, Cellular functions and Late endosome.
Her Endoplasmic reticulum research includes elements of Vesicle, Immunoelectron microscopy and Microscopy. Her Endocytic cycle research integrates issues from Colloidal gold, Fiducial marker and Fluorescence microscope. Her work carried out in the field of Autophagy brings together such families of science as Transcriptome, PI3K/AKT/mTOR pathway, Epigenetics and Transcriptional regulation.
Judith Klumperman focuses on Cell biology, Autophagy, Endosome, Organelle and Fiducial marker. Her biological study focuses on Regeneration. Judith Klumperman has included themes like Transcriptome, Epigenetics and Transcriptional regulation in her Autophagy study.
Her research integrates issues of Golgi apparatus, Knockout mouse, Signal transducing adaptor protein and Hereditary spastic paraplegia in her study of Endosome. Judith Klumperman interconnects Ubiquitin, Caenorhabditis elegans, TFEB, Ubiquitin-conjugating enzyme and PI3K/AKT/mTOR pathway in the investigation of issues within Organelle. Her Fiducial marker research incorporates themes from Colloidal gold, Correlative light and electron microscopy, Biomedical engineering and Fluorophore.
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Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function
Paul Saftig;Judith Klumperman.
Nature Reviews Molecular Cell Biology (2009)
Termination of autophagy and reformation of lysosomes regulated by mTOR
Li Yu;Christina K. McPhee;Christina K. McPhee;Lixin Zheng;Gonzalo A. Mardones;Gonzalo A. Mardones.
Trafficking and function of the tetraspanin CD63.
Maaike S. Pols;Judith Klumperman.
Experimental Cell Research (2009)
Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1-deficient mice.
Mario Pende;Sara C. Kozma;Muriel Jaquet;Viola Oorschot.
Endocytosis and Sorting of ErbB2 and the Site of Action of Cancer Therapeutics Trastuzumab and Geldanamycin
Cary D. Austin;Ann M. De Mazière;Paul I. Pisacane;Suzanne M. van Dijk.
Molecular Biology of the Cell (2004)
Sorting Nexin-1 Mediates Tubular Endosome-to-TGN Transport through Coincidence Sensing of High- Curvature Membranes and 3-Phosphoinositides
Jez Carlton;Miriam Bujny;Brian J. Peter;Viola M.J. Oorschot.
Current Biology (2004)
Bilayered Clathrin Coats on Endosomal Vacuoles Are Involved in Protein Sorting toward Lysosomes
Martin Sachse;Sylvie Urbé;Viola Oorschot;Ger J. Strous.
Molecular Biology of the Cell (2002)
Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents
Michael Degtyarev;Ann De Mazière;Christine Orr;Jie Lin.
Journal of Cell Biology (2008)
Vesicular Tubular Clusters between the ER and Golgi Mediate Concentration of Soluble Secretory Proteins by Exclusion from COPI-Coated Vesicles
José A. Martínez-Menárguez;Hans J. Geuze;Jan W. Slot;Judith Klumperman.
Syntaxin 13 Mediates Cycling of Plasma Membrane Proteins via Tubulovesicular Recycling Endosomes
Rytis Prekeris;Judith Klumperman;Yu A. Chen;Richard H. Scheller.
Journal of Cell Biology (1998)
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