World's Best Scientists 2026 revealed!
Ger J. Strous

Ger J. Strous

D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
15244
World Ranking
9140
National Ranking
244

Overview

Ger J. Strous is affiliated with BIMINI Biotech in the Netherlands, with a research focus spanning medicine and biochemistry, genetics, and molecular biology. Their work predominantly covers areas within endocrinology, metabolism, molecular biology, and oncology, addressing mechanisms that intersect with cancer and chronic diseases.

Their recent scholarly contributions include the following publications:

  • Growth Hormone Receptor Regulation in Cancer and Chronic Diseases, 2020, Frontiers in Endocrinology
  • Small molecules to regulate the GH/IGF1 axis by inhibiting the growth hormone receptor synthesis, 2022, Frontiers in Endocrinology
  • WIP1 is a novel specific target for growth hormone action, 2023, iScience
  • A novel antifolate suppresses growth of FPGS-deficient cells and overcomes methotrexate resistance, 2023, Life Science Alliance
  • A novel antifolate suppresses growth of FPGS-deficient cells and overcomes methotrexate resistance, 2023, bioRxiv (Cold Spring Harbor Laboratory)

Strous collaborates regularly with a group of coauthors, including:

  • Jan A. Mol
  • Elpetra P.M. Timmermans-Sprang
  • Judith Klumperman
  • Peter Maas
  • Vera Chesnokova

The researcher publishes frequently in several scientific journals and venues such as:

  • Frontiers in Endocrinology
  • iScience
  • Life Science Alliance
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Pharmaceuticals

Key research topics addressed by Strous focus on:

  • Growth Hormone and Insulin-like Growth Factors
  • Cancer, Hypoxia, and Metabolism
  • Biochemical and Molecular Research
  • Folate and B Vitamins Research
  • Acute Myeloid Leukemia Research
  • Cytokine Signaling Pathways and Interactions
  • PI3K/AKT/mTOR signaling in cancer

Within the broader fields of study, their work primarily involves:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Subfields of emphasis include:

  • Endocrinology, Diabetes and Metabolism
  • Molecular Biology
  • Oncology
  • Cancer Research
  • Rheumatology

Best Publications

  • Mucin-type glycoproteins.

    Ger J. Strous;Jan Dekker

  • Intracellular site of asialoglycoprotein receptor-ligand uncoupling: Double-label immunoelectron microscopy during receptor-mediated endocytosis

    Hans J. Geuze;Jan Willem Slot;Ger J.A.M. Strous;Harvey F. Lodish

  • Hepatoma secretory proteins migrate from rough endoplasmic reticulum to Golgi at characteristic rates

    Harvey F. Lodish;Nancy Kong;Martin Snider;Martin Snider;Ger J. A. M. Strous;Ger J. A. M. Strous

  • Intracellular transport of secretory and membrane proteins in hepatoma cells infected by vesicular stomatitis virus

    Ger J.A.M. Strous;Harvey F. Lodish

  • Bilayered Clathrin Coats on Endosomal Vacuoles Are Involved in Protein Sorting toward Lysosomes

    Martin Sachse;Sylvie Urbé;Viola Oorschot;Ger J. Strous

  • The ubiquitin conjugation system is required for ligand-induced endocytosis and degradation of the growth hormone receptor.

    G J Strous;P van Kerkhof;R Govers;A Ciechanover

  • Late endosomes derive from early endosomes by maturation

    Willem Stoorvogel;Ger J. Strous;Hans J. Geuze;Viola Oorschot

  • Wnt signals are transmitted through N‐terminally dephosphorylated β‐catenin

    Frank J T Staal;Mascha van Noort;Ger J Strous;Hans C Clevers

  • Intracellular receptor sorting during endocytosis: comparative immunoelectron microscopy of multiple receptors in rat liver.

    Hans J. Geuze;Jan W. Slot;Ger J.A.M. Strous;Jane Peppard

  • 39 kDa receptor-associated protein is an ER resident protein and molecular chaperone for LDL receptor-related protein.

    Guojun Bu;H. J. Geuze;G. J. Strous;A. L. Schwartz

  • Sorting of mannose 6-phosphate receptors and lysosomal membrane proteins in endocytic vesicles.

    H J Geuze;W Stoorvogel;G J Strous;J W Slot

  • Endocytosis of GPI-linked membrane folate receptor-alpha.

    Simon Rijnboutt;Gerrit Jansen;George Posthuma;John B. Hynes

  • Identification of a novel ubiquitin conjugation motif, required for ligand-induced internalization of the growth hormone receptor.

    Roland Govers;Toine ten Broeke;Peter van Kerkhof;Alan L. Schwartz

  • The YXXL Motif, but Not the Two NPXY Motifs, Serves as the Dominant Endocytosis Signal for Low Density Lipoprotein Receptor-related Protein

    Yonghe Li;Maria Paz Marzolo;Peter van Kerkhof;Ger J. Strous

  • Ligand-independent growth hormone receptor dimerization occurs in the endoplasmic reticulum and is required for ubiquitin system-dependent endocytosis

    Jürgen Gent;Peter van Kerkhof;Marcel Roza;Guojun Bu

  • Endocytosis and Degradation of the Growth Hormone Receptor Are Proteasome-dependent

    Peter van Kerkhof;Roland Govers;Cristina M. Alves dos Santos;Ger J. Strous

  • Mannose 6-phosphate-independent membrane association of cathepsin D, glucocerebrosidase, and sphingolipid-activating protein in HepG2 cells.

    S. Rijnboutt;H. M. F. G. Aerts;H. J. Geuze;J. M. Tager

  • Sorting of endocytosed transferrin and asialoglycoprotein occurs immediately after internalization in HepG2 cells.

    W Stoorvogel;H J Geuze;G J Strous

  • Sorting nexin 17 facilitates LRP recycling in the early endosome

    Peter van Kerkhof;Peter van Kerkhof;Jiyeon Lee;Lynn McCormick;Elena Tetrault

  • The UIM domain of Hrs couples receptor sorting to vesicle formation.

    Sylvie Urbé;Martin Sachse;Paula E. Row;Christian Preisinger

Frequent Co-Authors

Hans J. Geuze
Hans J. Geuze Utrecht University
Alan L. Schwartz
Alan L. Schwartz Washington University in St. Louis
Judith Klumperman
Judith Klumperman Utrecht University
Guojun Bu
Guojun Bu Hong Kong University of Science and Technology
Willem Stoorvogel
Willem Stoorvogel Utrecht University
Jan W. Slot
Jan W. Slot Utrecht University
Viola Oorschot
Viola Oorschot Utrecht University
Hans Bloemendal
Hans Bloemendal Radboud University
Aaron Ciechanover
Aaron Ciechanover Technion – Israel Institute of Technology

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Considering a future in Biology or Biochemistry can open many doors in health science, research, and clinical practice. Today, flexible education options make it easier than ever to advance your expertise, whether you want to focus on nutrition, nursing, or healthcare management.

If you’re interested in how diet and health intersect, exploring an accelerated nutrition degree online can provide a fast track to a rewarding career as a dietitian or nutritionist. Registered nurses looking to further their credentials may benefit from the easiest rn to bsn online program, which is structured for working professionals and can help boost career prospects in patient care.

Those with an interest in management roles may consider a masters degree in healthcare management, giving a strong foundation in leadership and administration within the health sector. For students passionate about mental health, specialized psych nurse practitioner programs enable graduates to deliver much-needed mental health services in a variety of settings.

By taking advantage of these online learning pathways, students can tailor their education to suit their career goals within the dynamic fields of biology, biochemistry, and healthcare.

Best Scientists Citing Ger J. Strous

Trending Scientists