World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
28708
World Ranking
12883
National Ranking
1006

Overview

Sylvie Urbé is affiliated with the University of Liverpool in the United Kingdom and has contributed to research primarily in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work encompasses several subfields including Molecular Biology, Epidemiology, Immunology, Oncology, and Cell Biology.

The scientist's research topics cover a range of subjects with notable focus areas including:

  • Ubiquitin and proteasome pathways
  • Autophagy in Disease and Therapy
  • Mitochondrial Function and Pathology
  • Peptidase Inhibition and Analysis
  • Interferon and immune responses
  • Cellular transport and secretion
  • Parkinson's Disease Mechanisms and Treatments

Among their recent publications are:

  • USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylation, 2020, Life Science Alliance
  • Protein degradation on the global scale, 2022, Molecular Cell
  • Benchmarking a highly selective USP30 inhibitor for enhancement of mitophagy and pexophagy, 2021, Life Science Alliance
  • FBXL4 ubiquitin ligase deficiency promotes mitophagy by elevating NIX levels, 2023, The EMBO Journal
  • The deubiquitylase USP9X controls ribosomal stalling, 2020, The Journal of Cell Biology

The scientist frequently collaborates with several co-authors, including:

  • Michael J. Clague
  • Emma V. Rusilowicz-Jones
  • Francesco G. Barone
  • Heather Mortiboys
  • Hannah Elcocks

Sylvie Urbé's work has been published across multiple venues, reflecting the interdisciplinary nature of their research. These include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Life Science Alliance
  • The Journal of Cell Biology
  • Biochemical Journal
  • Molecular Cell

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Breaking the chains: structure and function of the deubiquitinases.

    David Komander;Michael J. Clague;Sylvie Urbé

  • Rab11 regulates recycling through the pericentriolar recycling endosome.

    O Ullrich;S Reinsch;S Urbé;M Zerial

  • The emerging shape of the ESCRT machinery

    Roger L. Williams;Sylvie Urbé

  • Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation

    Hannah E.J. Polson;Jane de Lartigue;Daniel J. Rigden;Marco Reedijk

  • Breaking the chains: deubiquitylating enzyme specificity begets function.

    Michael J Clague;Sylvie Urbé;David Komander

  • Ubiquitin: same molecule, different degradation pathways.

    Michael J. Clague;Sylvie Urbé

  • Vacuolar ATPase activity is required for endosomal carrier vesicle formation.

    Michael J. Clague;Sylvie Urbé;Fernando Aniento;Jean Gruenberg

  • Bilayered Clathrin Coats on Endosomal Vacuoles Are Involved in Protein Sorting toward Lysosomes

    Martin Sachse;Sylvie Urbé;Viola Oorschot;Ger J. Strous

  • Deubiquitylases From Genes to Organism

    Michael J. Clague;Igor Barsukov;Judy M. Coulson;Han Liu

  • AMSH is an endosome-associated ubiquitin isopeptidase

    John McCullough;Michael J. Clague;Sylvie Urbé

  • Molecular basis of USP7 inhibition by selective small-molecule inhibitors

    Andrew P. Turnbull;Stephanos Ioannidis;Wojciech W. Krajewski;Adan Pinto-Fernandez

  • The demographics of the ubiquitin system.

    Michael J. Clague;Claire Heride;Sylvie Urbé

  • Endocytosis: the DUB version.

    Michael J. Clague;Sylvie Urbé

  • Rab11, a small GTPase associated with both constitutive and regulated secretory pathways in PC12 cells.

    S. Urbé;L.A. Huber;M. Zerial;S.A. Tooze

  • The Ubiquitin Isopeptidase UBPY Regulates Endosomal Ubiquitin Dynamics and Is Essential for Receptor Down-regulation

    Paula E. Row;Ian A. Prior;John McCullough;Michael J. Clague

  • PIKfyve Regulation of Endosome‐Linked Pathways

    Jane de Lartigue;Hannah Polson;Morri Feldman;Kevan Shokat

  • Met/Hepatocyte growth factor receptor ubiquitination suppresses transformation and is required for Hrs phosphorylation.

    Jasmine V. Abella;Pascal Peschard;Monica A. Naujokas;Tong Lin

  • Cellular functions of the DUBs.

    Michael J. Clague;Judy M. Coulson;Sylvie Urbé

  • Activation of the endosome-associated ubiquitin isopeptidase AMSH by STAM, a component of the multivesicular body-sorting machinery

    John McCullough;Paula E. Row;Óscar Lorenzo;Mary Doherty

Frequent Co-Authors

Michael J. Clague
Michael J. Clague University of Liverpool
David Komander
David Komander Walter and Eliza Hall Institute of Medical Research
Daniel J. Rigden
Daniel J. Rigden University of Liverpool
Sharon A. Tooze
Sharon A. Tooze The Francis Crick Institute
Benedikt M. Kessler
Benedikt M. Kessler University of Oxford
Simon J. Davis
Simon J. Davis University of Oxford
Axel Behrens
Axel Behrens Imperial College London
Ian A. Prior
Ian A. Prior University of Liverpool
Ian G. Mills
Ian G. Mills University of Oxford
Graça Raposo
Graça Raposo Institut Curie

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Sylvie Urbé

Trending Scientists

Recently Published Articles