D-Index & Metrics Best Publications
Henry D. Appelman

Henry D. Appelman

University of Michigan–Ann Arbor
United States

Overview

What is he best known for?

The fields of study he is best known for:

  • Cancer
  • Internal medicine
  • Gene

Internal medicine, Pathology, Gastroenterology, Biopsy and Ulcerative colitis are his primary areas of study. His work deals with themes such as Endocrinology and Surgery, which intersect with Internal medicine. His studies deal with areas such as Carcinogenesis, Cancer and Stomach as well as Pathology.

The various areas that Henry D. Appelman examines in his Gastroenterology study include Predictive value of tests and Immunology. His Biopsy research integrates issues from Imaging phantom, Magnetic resonance imaging, Nonalcoholic fatty liver disease and Intraepithelial lymphocyte. His study in Ulcerative colitis is interdisciplinary in nature, drawing from both Colitis, Inflammatory bowel disease, Retrospective cohort study, Colonoscopy and Endoscopy.

His most cited work include:

  • Dysplasia in inflammatory bowel disease: Standardized classification with provisional clinical applications (1555 citations)
  • Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis. (836 citations)
  • Hepatic fat fraction: MR imaging for quantitative measurement and display--early experience. (250 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Pathology, Internal medicine, Gastroenterology, Esophagus and Biopsy. His Pathology research includes themes of Cancer and Adenocarcinoma. His study focuses on the intersection of Cancer and fields such as Cancer research with connections in the field of In vivo.

His Internal medicine study integrates concerns from other disciplines, such as Endocrinology and Oncology. His study looks at the relationship between Gastroenterology and fields such as Ulcerative colitis, as well as how they intersect with chemical problems. His Biopsy study frequently links to other fields, such as Endoscopy.

He most often published in these fields:

  • Pathology (39.16%)
  • Internal medicine (41.44%)
  • Gastroenterology (33.46%)

What were the highlights of his more recent work (between 2015-2021)?

  • Cancer research (9.13%)
  • Internal medicine (41.44%)
  • Pathology (39.16%)

In recent papers he was focusing on the following fields of study:

Henry D. Appelman spends much of his time researching Cancer research, Internal medicine, Pathology, Gastroenterology and Colorectal cancer. His research integrates issues of Stem cell and In vivo in his study of Cancer research. His Oncology research extends to the thematically linked field of Internal medicine.

His studies in Pathology integrate themes in fields like Gut permeability and Confocal laser endomicroscopy. His work carried out in the field of Gastroenterology brings together such families of science as Esophagitis, Low grade dysplasia, Disease, Sessile serrated adenoma and Hyperplastic Polyp. Henry D. Appelman works mostly in the field of Colorectal cancer, limiting it down to topics relating to Adenoma and, in certain cases, Colonoscopy, as a part of the same area of interest.

Between 2015 and 2021, his most popular works were:

  • ATRX loss promotes tumor growth and impairs nonhomologous end joining DNA repair in glioma (125 citations)
  • Identification, isolation and characterization of human LGR5-positive colon adenoma cells. (42 citations)
  • Gastroblastoma harbors a recurrent somatic MALAT1 – GLI1 fusion gene (36 citations)

In his most recent research, the most cited papers focused on:

  • Cancer
  • Internal medicine
  • Gene

Henry D. Appelman mainly focuses on Cancer research, Stem cell, Cancer, Colorectal cancer and Pathology. His Cancer research research is multidisciplinary, incorporating perspectives in Non-homologous end joining, DNA repair, Microsatellite instability, ATRX and Histone. His work in Stem cell tackles topics such as Carcinogenesis which are related to areas like Stem cell marker, Cell growth, Colitis, Angiogenesis and PI3K/AKT/mTOR pathway.

He interconnects Protein kinase B, Mechanistic target of rapamycin, Immunology and Genetic predisposition in the investigation of issues within Cancer. His Pathology research includes elements of GLI1 and Hedgehog signaling pathway. His research on Liver function is centered around Internal medicine and Gastroenterology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Dysplasia in inflammatory bowel disease: Standardized classification with provisional clinical applications

Robert H. Riddell;Harvey Goldman;David F. Ransohoff;Henry D. Appelman.
Human Pathology (1983)

2615 Citations

Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis.

Emina H. Huang;Mark J. Hynes;Tao Zhang;Tao Zhang;Christophe Ginestier.
Cancer Research (2009)

1208 Citations

Achalasia. A morphologic study of 42 resected specimens.

John R. Goldblum;Richard I. Whyte;Mark B. Orringer;Henry D. Appelman.
The American Journal of Surgical Pathology (1994)

382 Citations

Arteriovenous Malformations of the Gastrointestinal Tract

John D. Moore;Norman W. Thompson;Henry D. Appelman;Dennis Foley.
Archives of Surgery (1976)

381 Citations

Hepatic fat fraction: MR imaging for quantitative measurement and display--early experience.

Hero K. Hussain;Thomas L. Chenevert;Frank J. Londy;Vikas Gulani.
Radiology (2005)

334 Citations

Histopathology differentiates acute self-limited colitis from ulcerative colitis.

Timothy T. Nostrant;Neelam B. Kumar;Henry D. Appelman.
Gastroenterology (1987)

310 Citations

Aldehyde dehydrogenase-expressing colon stem cells contribute to tumorigenesis in the transition from colitis to cancer.

Joseph E. Carpentino;Mark J. Hynes;Henry D. Appelman;Tong Zheng.
Cancer Research (2009)

286 Citations

Clinical, epidemiologic, and morphologic comparison between adenocarcinomas arising in Barrett's esophageal mucosa and in the gastric cardia

Randy J. Kalish;Paul E. Clancy;Mark B. Orringer;Henry D. Appelman.
Gastroenterology (1984)

285 Citations

Microallelotyping defines the sequence and tempo of allelic losses at tumour suppressor gene loci during colorectal cancer progression

C. Richard Boland;Juichi Sato;Juichi Sato;Henry D. Appelman;Robert S. Bresalier.
Nature Medicine (1995)

272 Citations

Loss of CDX2 Expression and Microsatellite Instability Are Prominent Features of Large Cell Minimally Differentiated Carcinomas of the Colon

Takao Hinoi;Masachika Tani;Masachika Tani;Peter C. Lucas;Karel Caca.
American Journal of Pathology (2001)

267 Citations

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