Andreas Brech focuses on Cell biology, Autophagy, Endosome, ESCRT and Endocytic cycle. His work deals with themes such as Biochemistry and BAG3, which intersect with Cell biology. His research integrates issues of Cytoplasm, Programmed cell death, Intracellular and Cancer research in his study of Autophagy.
The various areas that he examines in his Endosome study include Microtubule, Endocytosis and TLR4. Andreas Brech has researched Endocytic cycle in several fields, including Dynein, Kinesin, Endoplasmic reticulum and Cell membrane. His work carried out in the field of Sequestosome-1 Protein brings together such families of science as MAP1LC3B, Nuclear protein and Sequestosome 1.
His main research concerns Cell biology, Endosome, Autophagy, Endocytic cycle and Endocytosis. His studies deal with areas such as Receptor, Biochemistry and Vesicle as well as Cell biology. Andreas Brech has included themes like Transport protein, Dynein, Epidermal growth factor and GTPase in his Endosome study.
His Autophagy study combines topics from a wide range of disciplines, such as Biophysics, Programmed cell death, Protein degradation and Cytoplasm. Andreas Brech works mostly in the field of Endocytic cycle, limiting it down to concerns involving Phosphatidylinositol and, occasionally, Retromer. He combines subjects such as Transferrin receptor, Internalization and Gap junction with his study of Endocytosis.
The scientist’s investigation covers issues in Cell biology, Autophagy, ESCRT, Endosome and Biophysics. Protein degradation, Microtubule, Retromer, Phosphatidylinositol and Lamin are subfields of Cell biology in which his conducts study. His biological study spans a wide range of topics, including Anabolism, Motility, Wasting, Muscle atrophy and Metabolism.
His work in ESCRT tackles topics such as Membrane fission which are related to areas like Mitotic exit and Inner membrane. His research in Endosome intersects with topics in Epithelium, GTPase and Mitophagy. His work in Biophysics covers topics such as Receptor which are related to areas like Cell, Intracellular and Cell type.
Andreas Brech mainly focuses on Cell biology, Autophagy, ESCRT, Mitophagy and Endosome. In his works, he undertakes multidisciplinary study on Cell biology and Autophagy-related protein 13. His study in Fragmentation is interdisciplinary in nature, drawing from both Membrane fission and Compartmentalization.
His Centriolar satellite research includes themes of Centriole, Microtubule, Mitosis and Chromosome segregation. His Cell study combines topics in areas such as Receptor, Degranulation, Cytokine and Intracellular. The various areas that Andreas Brech examines in his Cytokine study include Innate immune system and Cell type.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Guidelines for the use and interpretation of assays for monitoring autophagy
Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham.
Autophagy (2012)
p62/SQSTM1 Binds Directly to Atg8/LC3 to Facilitate Degradation of Ubiquitinated Protein Aggregates by Autophagy
Serhiy Pankiv;Terje Høyvarde Clausen;Trond Lamark;Andreas Brech.
Journal of Biological Chemistry (2007)
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
Geir Bjørkøy;Trond Lamark;Andreas Brech;Heidi Outzen.
Journal of Cell Biology (2005)
EEA1 links PI(3)K function to Rab5 regulation of endosome fusion
Anne Simonsen;Roger Lippé;Savvas Christoforidis;Jean Michel Gaullier.
Nature (1998)
Monitoring autophagic degradation of p62/SQSTM1.
Geir Bjørkøy;Trond Lamark;Serhiy Pankiv;Aud Øvervatn.
Methods in Enzymology (2009)
Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease
Maria Filimonenko;Susanne Stuffers;Camilla Raiborg;Ai Yamamoto.
Journal of Cell Biology (2007)
The Adaptor Protein p62/SQSTM1 Targets Invading Bacteria to the Autophagy Pathway
Yiyu T. Zheng;Shahab Shahnazari;Andreas Brech;Trond Lamark.
Journal of Immunology (2009)
Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila.
Anne Simonsen;Robert C. Cumming;Robert C. Cumming;Andreas Brech;Pauline Isakson;Pauline Isakson.
Autophagy (2008)
FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end–directed vesicle transport
Serhiy Pankiv;Endalkachew A. Alemu;Andreas Brech;Jack Ansgar Bruun.
Journal of Cell Biology (2010)
Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes.
Kristi G. Bache;Andreas Brech;Anja Mehlum;Harald Alfred Stenmark.
Journal of Cell Biology (2003)
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