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Biology and Biochemistry

D-Index
66
Citations
13765
World Ranking
8786
National Ranking
3928

Overview

Robert C. Piper is affiliated with the University of Iowa in the United States and has contributed extensively to research in the fields of Biochemistry, Genetics, and Molecular Biology as well as Medicine.

Their work spans several subfields including Molecular Biology, Cell Biology, Cellular and Molecular Neuroscience, Genetics, and Neurology. The main research topics include:

  • Cellular transport and secretion
  • Hereditary Neurological Disorders
  • Ubiquitin and proteasome pathways
  • Endoplasmic Reticulum Stress and Disease
  • Autophagy in Disease and Therapy
  • RNA Research and Splicing
  • Protein Degradation and Inhibitors

Some of the recent papers by Robert C. Piper highlight their focus on molecular mechanisms and cellular pathways. Notable publications include:

  • Functional Genomic Screening Independently Identifies CUL3 as a Mediator of Vemurafenib Resistance via Src-Rac1 Signaling Axis, 2020, Frontiers in Oncology
  • A Cycle of Ubiquitination Regulates Adaptor Function of the Nedd4-Family Ubiquitin Ligase Rsp5, 2020, Current Biology
  • Selective endocytosis of Ca 2+ -permeable AMPARs by the Alzheimer's disease risk factor CALM bidirectionally controls synaptic plasticity, 2022, Science Advances
  • Bro1 stimulates Vps4 to promote intralumenal vesicle formation during multivesicular body biogenesis, 2021, The Journal of Cell Biology
  • Dynein-Mediated Trafficking: A New Mechanism of Diabetic Podocytopathy, 2022, Kidney360

Robert C. Piper frequently collaborates with other researchers. Frequent co-authors include:

  • Natalya Pashkova
  • Tabitha A. Peterson
  • Stanley C. Winistorfer
  • Christopher P. Ptak
  • Christopher A. Ahern

Their publications appear in several scientific venues, with repeated contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Cell Biology
  • Brain
  • Frontiers in Oncology
  • Current Biology

Best Publications

  • Parasite Lactate Dehydrogenase as an Assay for Plasmodium falciparum Drug Sensitivity

    M. T. Makler;J. M. Ries;J. A. Williams;J. E. Bancroft

  • Biogenesis and Function of Multivesicular Bodies

    Robert C. Piper;David J. Katzmann

  • VPS27 controls vacuolar and endocytic traffic through a prevacuolar compartment in Saccharomyces cerevisiae.

    Robert C. Piper;Antony A. Cooper;Hong Yang;Tom H. Stevens

  • The Vps27p Hse1p complex binds ubiquitin and mediates endosomal protein sorting.

    Patricia S. Bilodeau;Jennifer L. Urbanowski;Stanley C. Winistorfer;Robert C. Piper

  • Lysosome-endosome fusion and lysosome biogenesis.

    J.P. Luzio;B.A. Rous;N.A. Bright;P.R. Pryor

  • Svp1p defines a family of phosphatidylinositol 3,5-bisphosphate effectors

    Stephen K Dove;Robert C Piper;Robert K McEwen;Jong W Yu

  • Immunocapture diagnostic assays for malaria using Plasmodium lactate dehydrogenase (pLDH).

    Robert Piper;Jacques Lebras;Laura Wentworth;Angela Hunt-Cooke

  • Insights into Ubiquitin Transfer Cascades from a Structure of a UbcH5B∼Ubiquitin-HECTNEDD4L Complex

    Hari B. Kamadurai;Judith Souphron;Daniel C. Scott;David M. Duda

  • Combinatorial SNARE complexes with VAMP7 or VAMP8 define different late endocytic fusion events.

    Paul R Pryor;Barbara M Mullock;Nicholas A Bright;Margaret R Lindsay

  • Differential sorting of two glucose transporters expressed in insulin-sensitive cells.

    R. C. Piper;L. J. Hess;D. E. James

  • Late endosomes: sorting and partitioning in multivesicular bodies.

    Robert C. Piper;J. Paul Luzio

  • Ubiquitin-Dependent Sorting in Endocytosis

    Robert C. Piper;Ivan Dikic;Gergely L. Lukacs

  • Loss of Vac14, a regulator of the signaling lipid phosphatidylinositol 3,5-bisphosphate, results in neurodegeneration in mice

    Yanling Zhang;Sergey N. Zolov;Clement Y. Chow;Shalom G. Slutsky

  • Vps27-Hse1 and ESCRT-I complexes cooperate to increase efficiency of sorting ubiquitinated proteins at the endosome

    Patricia S. Bilodeau;Stanley C. Winistorfer;William R. Kearney;Andrew D. Robertson

  • The iron transporter Fth1p forms a complex with the Fet5 iron oxidase and resides on the vacuolar membrane.

    Jennifer L. Urbanowski;Robert C. Piper

  • How Ubiquitin Functions with ESCRTs

    S. Brookhart Shields;Robert C. Piper

  • Membrane dynamics and the biogenesis of lysosomes (Review)

    J Paul Luzio;Viviane Poupon;Margaret R Lindsay;Barbara M Mullock

  • Ubiquitin-dependent sorting of integral membrane proteins for degradation in lysosomes

    Robert C Piper;J Paul Luzio

  • GGA proteins bind ubiquitin to facilitate sorting at the trans-Golgi network

    Patricia M. Scott;Patricia S. Bilodeau;Olga Zhdankina;Stanley C. Winistorfer

  • The membrane protein alkaline phosphatase is delivered to the vacuole by a route that is distinct from the VPS-dependent pathway

    Robert C. Piper;Nia J. Bryant;Tom H. Stevens

Frequent Co-Authors

David E. James
David E. James University of Sydney
J. Paul Luzio
J. Paul Luzio University of Cambridge
Jan W. Slot
Jan W. Slot Utrecht University
Nicholas A. Bright
Nicholas A. Bright University of Cambridge
Tom H. Stevens
Tom H. Stevens University of Oregon
Peng Xu
Peng Xu Chinese Academy of Sciences
Brenda A. Schulman
Brenda A. Schulman Max Planck Society
Todd R. Graham
Todd R. Graham Vanderbilt University
John C. Lawrence
John C. Lawrence University of Virginia
Wilbur K. Milhous
Wilbur K. Milhous Clemson University

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