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Molecular Biology

D-Index
64
Citations
28906
World Ranking
1696
National Ranking
11

Overview

Claus L. Andersen is affiliated with Aarhus University Hospital in Denmark and has contributed extensively across multiple fields related to cancer research and molecular biology. Their research primarily focuses on Cancer Genomics and Diagnostics, with a significant emphasis on colorectal cancer.

The main fields of study covered in Andersen's academic work include Medicine and Biochemistry, Genetics and Molecular Biology. Within these domains, the scientist has concentrated on subfields such as Cancer Research, Oncology, Pathology and Forensic Medicine, Molecular Biology, and Pulmonary and Respiratory Medicine.

Key topics addressed in their research include:

  • Cancer Genomics and Diagnostics
  • Genetic factors in colorectal cancer
  • Colorectal Cancer Treatments and Studies
  • Colorectal Cancer Screening and Detection
  • Colorectal Cancer Surgical Treatments
  • Molecular Biology Techniques and Applications
  • Single-cell and spatial transcriptomics

Andersen has published research in several venues frequently, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Nature Communications
  • Annals of Oncology
  • Journal of Clinical Oncology

They have coauthored works with several researchers repeatedly, notably:

  • Tenna Vesterman Henriksen
  • Amanda Frydendahl
  • Mads H. Rasmussen
  • Kåre Andersson Gotschalck
  • Christina Demuth

Among their recent published papers are:

  • "Detection and characterization of lung cancer using cell-free DNA fragmentomes," 2021, Nature Communications
  • "The effect of surgical trauma on circulating free DNA levels in cancer patients-implications for studies of circulating tumor DNA," 2020, Molecular Oncology
  • "Incidence of Recurrence and Time to Recurrence in Stage I to III Colorectal Cancer," 2023, JAMA Oncology
  • "Cell-free DNA approaches for cancer early detection and interception," 2023, Journal for ImmunoTherapy of Cancer
  • "Ultrasensitive plasma-based monitoring of tumor burden using machine-learning-guided signal enrichment," 2024, Nature Medicine

Best Publications

  • Normalization of Real-Time Quantitative Reverse Transcription-PCR Data: A Model-Based Variance Estimation Approach to Identify Genes Suited for Normalization, Applied to Bladder and Colon Cancer Data Sets

    Claus Lindbjerg Andersen;Jens Ledet Jensen;Torben Falck Ørntoft

  • Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

    Jirina Bartkova;Nousin Rezaei;Michalis Liontos;Panagiotis Karakaidos

  • Direct detection of early-stage cancers using circulating tumor DNA

    Jillian Phallen;Mark Sausen;Vilmos Adleff;Alessandro Leal

  • Genome-wide cell-free DNA fragmentation in patients with cancer

    Stephen Cristiano;Alessandro Leal;Jillian Phallen;Jacob Fiksel

  • Diagnostic and Prognostic MicroRNAs in Stage II Colon Cancer

    Troels Schepeler;Jørgen T. Reinert;Marie S. Ostenfeld;Lise L. Christensen

  • p53-Responsive MicroRNAs 192 and 215 Are Capable of Inducing Cell Cycle Arrest

    Christian J. Braun;Xin Zhang;Irina Savelyeva;Sonja Wolff

  • A Dual Program for Translation Regulation in Cellular Proliferation and Differentiation

    Hila Gingold;Disa Tehler;Nanna R. Christoffersen;Morten M. Nielsen

  • Analysis of circulating tumour DNA to monitor disease burden following colorectal cancer surgery

    Thomas Reinert;Lone V. Schøler;Rune Thomsen;Heidi Tobiasen

  • An Optimized Shotgun Strategy for the Rapid Generation of Comprehensive Human Proteomes.

    Dorte B. Bekker-Jensen;Christian D. Kelstrup;Tanveer S. Batth;Sara C. Larsen

  • Genomic profiling of microRNAs in bladder cancer: miR-129 is associated with poor outcome and promotes cell death in vitro.

    Lars Dyrskjøt;Marie S. Ostenfeld;Jesper B. Bramsen;Asli N. Silahtaroglu

  • Alternative Splicing in Colon, Bladder, and Prostate Cancer Identified by Exon Array Analysis

    Kasper Thorsen;Karina D. Sørensen;Anne Sofie Brems-Eskildsen;Charlotte Modin

  • Next-generation sequencing of RNA and DNA isolated from paired fresh-frozen and formalin-fixed paraffin-embedded samples of human cancer and normal tissue.

    Jakob Hedegaard;Kasper Thorsen;Mette Katrine Lund;Anne-Mette K. Hein

  • Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage

    Jirina Bartkova;Nousin Rezaei;Michalis Liontos;Panagiotis Karakaidos

  • Dynamics of human DNA topoisomerases IIα and IIβ in living cells

    Unknown

  • Identification and validation of highly frequent CpG island hypermethylation in colorectal adenomas and carcinomas.

    Bodil Øster;Kasper Thorsen;Philippe Lamy;Philippe Lamy;Tomasz K. Wojdacz

  • SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization.

    Nkerorema Djodji Damas;Michela Marcatti;Christophe Côme;Lise Lotte Christensen

  • Evaluation of two commercial global miRNA expression profiling platforms for detection of less abundant miRNAs.

    Steffen G Jensen;Philippe Lamy;Mads H Rasmussen;Marie S Ostenfeld

  • SNHG16 is regulated by the Wnt pathway in colorectal cancer and affects genes involved in lipid metabolism

    Lise Lotte Christensen;Kirsten True;Mark P. Hamilton;Morten M. Nielsen

  • Putative cis -regulatory drivers in colorectal cancer

    Halit Ongen;Halit Ongen;Claus L. Andersen;Jesper B. Bramsen;Bodil Oster

  • Role of activating fibroblast growth factor receptor 3 mutations in the development of bladder tumors.

    Karsten Zieger;Lars Dyrskjøt;Carsten Wiuf;Jens L. Jensen

Frequent Co-Authors

Torben F. Ørntoft
Torben F. Ørntoft Aarhus University
Søren Laurberg
Søren Laurberg Aarhus University Hospital
Carsten Wiuf
Carsten Wiuf University of Copenhagen
Emmanouil T. Dermitzakis
Emmanouil T. Dermitzakis University of Geneva
Nils Brünner
Nils Brünner University of Copenhagen
Lauri A. Aaltonen
Lauri A. Aaltonen University of Helsinki
Mogens Madsen
Mogens Madsen Technical University of Denmark
Manel Esteller
Manel Esteller Josep Carreras Leukaemia Research Institute
Mogens Kruhøffer
Mogens Kruhøffer BioXpedia A/S
Jakob Skou Pedersen
Jakob Skou Pedersen Aarhus University

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