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Nobuyuki Shimozawa

Nobuyuki Shimozawa

D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
8683
World Ranking
15260
National Ranking
1078

Overview

Nobuyuki Shimozawa is affiliated with Gifu University in Japan, where the primary research focus encompasses biochemistry, genetics, and molecular biology, alongside medicine. Their work spans 47 publications in biochemistry, genetics, and molecular biology, with 16 focused on medicine. Subfields include molecular biology, clinical biochemistry, physiology, genetics, and immunology, highlighting a multidisciplinary approach to biomedical research.

Research topics covered by Shimozawa center around peroxisome proliferator-activated receptors, metabolism and genetic disorders, RNA regulation and disease, neurogenetic and muscular disorders research, RNA research and splicing, immune cell function and interaction, and cancer, hypoxia, and metabolism. This indicates a robust engagement with cellular and molecular mechanisms relevant to genetic and metabolic diseases.

Recent published papers include:

  • Prevalence of patients with lysosomal storage disorders and peroxisomal disorders: A nationwide survey in Japan, 2021, Molecular Genetics and Metabolism
  • POLR3A variants in striatal involvement without diffuse hypomyelination, 2020, Brain and Development
  • Positional determination of the carbon-carbon double bonds in unsaturated fatty acids mediated by solvent plasmatization using LC-MS, 2020, Scientific Reports
  • Advanced Diagnostic System and Introduction of Newborn Screening of Adrenoleukodystrophy and Peroxisomal Disorders in Japan, 2021, International Journal of Neonatal Screening
  • Hexacosenoyl-CoA is the most abundant very long-chain acyl-CoA in ATP binding cassette transporter D1-deficient cells, 2020, Journal of Lipid Research

Frequent co-authors in Shimozawa's collaborative work include Shigeo Takashima, Kayoko Toyoshi, Kazuo Kubota, Akiko Ohba, and Hiroki Kawai. These partnerships suggest active engagement with other researchers specializing in related biomedical fields.

The scientist's publications have been prominently featured in journals such as Brain and Development, Molecular Genetics and Metabolism, Endocrine Journal, Journal of Inherited Metabolic Disease, and Scientific Reports. The distribution of these venues indicates a focus on genetic, metabolic, and developmental biology research.

Best Publications

  • A human gene responsible for Zellweger syndrome that affects peroxisome assembly.

    Nobuyuki Shimozawa;Toshiro Tsukamoto;Yasuyuki Suzuki;Tadao Orii

  • Proteomic Analysis of Rat Liver Peroxisome PRESENCE OF PEROXISOME-SPECIFIC ISOZYME OF LON PROTEASE

    Miki Kikuchi;Naoya Hatano;Sadaki Yokota;Nobuyuki Shimozawa

  • Human PEX19: cDNA cloning by functional complementation, mutation analysis in a patient with Zellweger syndrome, and potential role in peroxisomal membrane assembly

    Yuji Matsuzono;Naohiko Kinoshita;Shigehiko Tamura;Nobuyuki Shimozawa

  • Mutation in PEX16 is causal in the peroxisome-deficient Zellweger syndrome of complementation group D.

    Masanori Honsho;Shigehiko Tamura;Nobuyuki Shimozawa;Yasuyuki Suzuki

  • d-3-Hydroxyacyl-CoA Dehydratase/d-3-Hydroxyacyl-CoA Dehydrogenase Bifunctional Protein Deficiency: A Newly Identified Peroxisomal Disorder

    Yasuyuki Suzuki;Ling Ling Jiang;Masayoshi Souri;Shoko Miyazawa

  • Standardization of complementation grouping of peroxisome-deficient disorders and the second Zellweger patient with peroxisomal assembly factor-1 (PAF-1) defect.

    N. Shimozawa;Y. Suzuki;T. Orii;A. Moser

  • Mutations in PEX10 Is the Cause of Zellweger Peroxisome Deficiency Syndrome of Complementation Group B

    Kanji Okumoto;Ryota Itoh;Nobuyuki Shimozawa;Yasuyuki Suzuki

  • PEX12, the Pathogenic Gene of Group III Zellweger Syndrome: cDNA Cloning by Functional Complementation on a CHO Cell Mutant, Patient Analysis, and Characterization of Pex12p

    Kanji Okumoto;Nobuyuki Shimozawa;Atsusi Kawai;Shigehiko Tamura

  • Diagnostic utility of whole exome sequencing in patients showing cerebellar and/or vermis atrophy in childhood

    Chihiro Ohba;Hitoshi Osaka;Mizue Iai;Sumimasa Yamashita

  • Peroxisome assembly factor-2, a putative ATPase cloned by functional complementation on a peroxisome-deficient mammalian cell mutant.

    Toshiro Tsukamoto;Satoshi Miura;Toshiki Nakai;Sadaki Yokota

  • Human PEX1 cloned by functional complementation on a CHO cell mutant is responsible for peroxisome-deficient Zellweger syndrome of complementation group I

    Shigehiko Tamura;Kanji Okumoto;Ryusuke Toyama;Nobuyuki Shimozawa

  • Human peroxisome assembly factor-2 (PAF-2): a gene responsible for group C peroxisome biogenesis disorder in humans.

    S. Fukuda;N. Shimozawa;Y. Suzuki;Z. Zhang

  • Gas chromatography/mass spectrometry analysis of very long chain fatty acids, docosahexaenoic acid, phytanic acid and plasmalogen for the screening of peroxisomal disorders.

    Yasuhiko Takemoto;Yasuyuki Suzuki;Ryoko Horibe;Nobuyuki Shimozawa

  • Mucopolysaccharidosis IV A: Molecular Cloning of the Human N-Acetylgalactosamine-6-sulfatase Gene (GALNS) and Analysis of the 5′-Flanking Region

    Yoshihiro Nakashima;Shunji Tomatsu;Toshinori Hori;Seiji Fukuda

  • Nonsense and temperature-sensitive mutations in PEX13 are the cause of complementation group H of peroxisome biogenesis disorders

    Nobuyuki Shimozawa;Yasuyuki Suzuki;Zhongyi Zhang;Atsushi Imamura

  • Complementation study of peroxisome-deficient disorders by immunofluorescence staining and characterization of fused cells.

    Shigehiro Yajima;Yasuyuki Suzuki;Nobuyuki Shimozawa;Seiji Yamaguchi

  • Animal cell mutants represent two complementation groups of peroxisome-defective Zellweger syndrome.

    N Shimozawa;T Tsukamoto;Y Suzuki;T Orii

  • Identification of a new complementation group of the peroxisome biogenesis disorders and PEX14 as the mutated gene

    Nobuyuki Shimozawa;Toshiro Tsukamoto;Tomoko Nagase;Yasuhiko Takemoto

  • Mutations in Novel Peroxin Gene PEX26 That Cause Peroxisome-Biogenesis Disorders of Complementation Group 8 Provide a Genotype-Phenotype Correlation

    Naomi Matsumoto;Shigehiko Tamura;Satomi Furuki;Non Miyata

  • Mucopolysaccharidosis IVA: screening and identification of mutations of the N-acetylgalactosamine-6-sulfate sulfatase gene

    Tatsuya Ogawa;Shunji Tomatsu;Seiji Fukuda;Atsushi Yamagishi

Frequent Co-Authors

Naomi Kondo
Naomi Kondo Gifu University
Yasuyuki Suzuki
Yasuyuki Suzuki Gifu University
Tadao Orii
Tadao Orii Gifu University
Shunji Tomatsu
Shunji Tomatsu Alfred I. duPont Hospital for Children
Yukio Fujiki
Yukio Fujiki Kyushu University
Takashi Osumi
Takashi Osumi University of Hyogo
Ronald J.A. Wanders
Ronald J.A. Wanders University of Amsterdam
Takashi Hashimoto
Takashi Hashimoto Shinshu University
Toshiyuki Fukao
Toshiyuki Fukao Gifu University
Seiji Yamaguchi
Seiji Yamaguchi Shimane University

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