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D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
23849
World Ranking
8474
National Ranking
3811

Overview

Gye Won Han is affiliated with the University of Southern California in the United States. Their research primarily falls within the field of Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology, Cellular and Molecular Neuroscience, Physiology, Pharmacology, and Materials Chemistry.

The scientist's work addresses several key topics, including:

  • Receptor Mechanisms and Signaling
  • Protein Structure and Dynamics
  • Neuroscience and Neuropharmacology Research
  • RNA and protein synthesis mechanisms
  • Chemical Synthesis and Analysis
  • Pharmacological Receptor Mechanisms and Effects
  • Adenosine and Purinergic Signaling

Gye Won Han has contributed to multiple papers, among which the following stand out:

  • Structural basis of ligand recognition and self-activation of orphan GPR52, 2020, Nature
  • Full-length human GLP-1 receptor structure without orthosteric ligands, 2020, Nature Communications
  • Structural basis of the activation of a metabotropic GABA receptor, 2020, Nature
  • Determination of the melanocortin-4 receptor structure identifies Ca 2+ as a cofactor for ligand binding, 2020, Science
  • Structural basis of GABA reuptake inhibition, 2022, Nature

The scientist frequently publishes in several prominent venues, which include:

  • Nature
  • Nature Communications
  • UNC Libraries
  • Journal of Medicinal Chemistry
  • Science

Collaboration is a significant aspect of their work, with several frequent co-authors:

  • Vadim Cherezov
  • Raymond C. Stevens
  • Vsevolod Katritch
  • Cornelius Gati
  • Yiran Wu

Best Publications

  • Structure of the human dopamine d3 receptor in complex with a d2/d3 selective antagonist.

    Ellen Y. T. Chien;Wei Liu;Qiang Zhao;Vsevolod Katritch

  • Structure of the human κ-opioid receptor in complex with JDTic

    Huixian Wu;Daniel Wacker;Mauro Mileni;Vsevolod Katritch

  • Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions

    Wei Liu;Eugene Chun;Aaron A. Thompson;Pavel Chubukov

  • Structure of the human histamine H1 receptor complex with doxepin.

    Tatsuro Shimamura;Tatsuro Shimamura;Mitsunori Shiroishi;Mitsunori Shiroishi;Simone Weyand;Hirokazu Tsujimoto

  • Structure of an Agonist-Bound Human A2A Adenosine Receptor

    Fei Xu;Huixian Wu;Vsevolod Katritch;Gye Won Han

  • Structure of the CCR5 Chemokine Receptor–HIV Entry Inhibitor Maraviroc Complex

    Qiuxiang Tan;Ya Zhu;Jian Li;Zhuxi Chen

  • Structural Features for Functional Selectivity at Serotonin Receptors

    Daniel Wacker;Chong Wang;Vsevolod Katritch;Gye Won Han

  • Crystal Structure of a Lipid G Protein–Coupled Receptor

    Michael A. Hanson;Christopher B. Roth;Euijung Jo;Mark T. Griffith

  • Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser

    Yanyong Kang;X. Edward Zhou;Xiang Gao;Yuanzheng He

  • Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography

    Uwe Weierstall;Daniel James;Chong Wang;Thomas A. White

  • Crystal Structure of the Human Cannabinoid Receptor CB2.

    Tian Hua;Kiran Vemuri;Mengchen Pu;Lu Qu;Lu Qu

  • Structure of a Class C GPCR Metabotropic Glutamate Receptor 1 Bound to an Allosteric Modulator

    Huixian Wu;Chong Wang;Karen J. Gregory;Karen J. Gregory;Gye Won Han

  • Structural Basis for Molecular Recognition at Serotonin Receptors

    Chong Wang;Yi Jiang;Yi Jiang;Jinming Ma;Jinming Ma;Huixian Wu

  • Structure of the human smoothened receptor bound to an antitumour agent

    Chong Wang;Huixian Wu;Vsevolod Katritch;Gye Won Han

  • Crystal structures of agonist-bound human cannabinoid receptor CB1

    Tian Hua;Kiran Vemuri;Spyros P. Nikas;Robert B. Laprairie

  • Serial femtosecond crystallography of G protein-coupled receptors.

    Wei Liu;Daniel Wacker;Cornelius Gati;Gye Won Han

  • Structure of the human glucagon class B G-protein-coupled receptor

    Fai Yiu Siu;Min He;Chris De Graaf;Gye Won Han

  • Structure of the human P2Y12 receptor in complex with an antithrombotic drug

    Kaihua Zhang;Jin Zhang;Zhan-Guo Gao;Dandan Zhang

  • Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine

    Ling Qin;Irina Kufareva;Lauren G. Holden;Chong Wang

  • Structure of the Angiotensin Receptor Revealed by Serial Femtosecond Crystallography

    Haitao Zhang;Hamiyet Unal;Cornelius Gati;Gye Won Han

Frequent Co-Authors

Scott A. Lesley
Scott A. Lesley Genomics Institute of the Novartis Research Foundation
Adam Godzik
Adam Godzik University of California, Riverside
Lukasz Jaroszewski
Lukasz Jaroszewski Discovery Institute
Raymond C. Stevens
Raymond C. Stevens University of Southern California
Sanjay Krishna
Sanjay Krishna The Ohio State University
Ian A. Wilson
Ian A. Wilson Scripps Research Institute
Keith O. Hodgson
Keith O. Hodgson Stanford University
Vadim Cherezov
Vadim Cherezov University of Southern California
Vsevolod Katritch
Vsevolod Katritch University of Southern California
Wei Liu
Wei Liu Medical College of Wisconsin

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