World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
49
Citations
6856
World Ranking
15003
National Ranking
3821

Overview

Chingkuang Tu is affiliated with the University of Florida in the United States. Their recent research output spans multiple fields including toxicology, molecular biology, oncology, pharmacology, and physical and theoretical chemistry. The scientist's work addresses significant topics such as pharmacovigilance and adverse drug reactions, colorectal cancer treatments and studies, drug-induced adverse reactions, enzyme function and inhibition, chemical reactions and mechanisms, synthesis, catalytic reactions, and aspects of health systems including economic evaluations and quality of life.

Recent publications by Tu include:

  • Inhibition of Carbonic Anhydrase Using SLC-149: Support for a Noncatalytic Function of CAIX in Breast Cancer, 2021, Journal of Medicinal Chemistry
  • Real-world safety of deucravacitinib: insights from the Food and Drug Administration Adverse Event Reporting System, 2025, International Journal of Clinical Pharmacy
  • Comprehensive post-marketing safety analysis of tildrakizumab: insights from the FDA adverse event reporting system, 2025, Expert Opinion on Drug Safety
  • Adverse events associated with vismodegib: insights from a real-world pharmacovigilance study using the FAERS database, 2025, Frontiers in Pharmacology

The scientist collaborates frequently with several coauthors, including Kaidi Zhao, Shengxiang Xiao, Yang Zhao, Mam Y. Mboge, and Jacob Combs. The collaboration with Kaidi Zhao is the most frequent, involving three joint publications.

Tu's publications appear in a variety of journals such as the International Journal of Clinical Pharmacy, Journal of Medicinal Chemistry, Expert Opinion on Drug Safety, and Frontiers in Pharmacology.

Best Publications

  • Role of histidine 64 in the catalytic mechanism of human carbonic anhydrase II studied with a site-specific mutant

    Chingkuang Tu;David N. Silverman;Cecilia Forsman;Bengt Harald Jonsson

  • Structural and Kinetic Characterization of Active-Site Histidine as a Proton Shuttle in Catalysis by Human Carbonic Anhydrase II

    Zoë Fisher;Jose A. Hernandez Prada;Chingkuang Tu;David Duda

  • Catalytic Properties of Human Manganese Superoxide Dismutase

    Jan-Ling Hsu;Yunsheng Hsieh;Chingkuang Tu;Don O'Connor

  • Atomic crystal and molecular dynamics simulation structures of human carbonic anhydrase II: insights into the proton transfer mechanism

    S.Z Fisher;C.M Maupin;M Budayova-Spano;L Govindasamy

  • Rate of exchange of water from the active site of human carbonic anhydrase C

    D. N. Silverman;C. K. Tu;S. Lindskog;G. C. Wynns

  • Detection of nitroxyl (HNO) by membrane inlet mass spectrometry.

    Meredith R. Cline;Chingkuang Tu;David N. Silverman;John P. Toscano

  • Structural and kinetic analysis of the chemical rescue of the proton transfer function of carbonic anhydrase II.

    David Duda;Chingkuang Tu;Minzhang Qian;Philip Laipis

  • Speeding Up Proton Transfer in a Fast Enzyme: Kinetic and Crystallographic Studies on the Effect of Hydrophobic Amino Acid Substitutions in the Active Site of Human Carbonic Anhydrase II.

    S.Z Fisher;C.K Tu;D Bhatt;L Govindasamy

  • Probing the active site of human manganese superoxide dismutase: the role of glutamine 143.

    Yunsheng Hsieh;Yue Guan;Chingkuang Tu;Peter J. Bratt

  • Purification and kinetic analysis of recombinant CA XII, a membrane carbonic anhydrase overexpressed in certain cancers

    Barbara Ulmasov;Abdul Waheed;Gul N. Shah;Jeffrey H. Grubb

  • Enhancement of the catalytic properties of human carbonic anhydrase III by site-directed mutagenesis.

    David A. Jewell;Chingkuang Tu;Shanthi R. Paranawithana;Susan M. Tanhauser

  • The catalytic properties of human carbonic anhydrase IX.

    Thomas Wingo;Chingkuang Tu;Philip J. Laipis;David N. Silverman

  • Kinetic and Spectroscopic Characterization of the Gamma-Carbonic Anhydrase from the Methanoarchaeon Methanosarcina thermophila†

    Birgit E. Alber;Christopher M. Colangelo;Jun Dong;Christina M. V. Stålhandske

  • Crystal structure of F65A/Y131C-methylimidazole carbonic anhydrase V reveals architectural features of an engineered proton shuttle.

    K.M. Jude;S.K. Wright;C. Tu;D.N. Silverman

  • Identification of a Novel Noncatalytic Bicarbonate Binding Site in Eubacterial beta-Carbonic Anhydrase.

    Jeff D. Cronk;Roger S. Rowlett;Kam Y. J. Zhang;Chingkuang Tu

  • Rate-equilibria relationships in intramolecular proton transfer in human carbonic anhydrase III.

    D. N. Silverman;Chingkuang Tu;Xian Chen;S. M. Tanhauser

  • Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties

    Caroli Genis;Katherine H. Sippel;Nicolette Case;Wengang Cao

  • Human Carbonic Anhydrase III: Structural and Kinetic Study of Catalysis and Proton Transfer

    D.M Duda;C Tu;S.Z Fisher;H An

  • Characterization of the Product-inhibited Complex in Catalysis by Human Manganese Superoxide Dismutase

    Amy S. Hearn;Chingkuang Tu;Harry S. Nick;David N. Silverman

  • Chemical rescue in catalysis by human carbonic anhydrases II and III.

    Haiqian An;Chingkuang Tu;David Duda;Ileana Montanez-Clemente

Frequent Co-Authors

David N. Silverman
David N. Silverman University of Florida
Robert McKenna
Robert McKenna University of Florida
Mavis Agbandje-McKenna
Mavis Agbandje-McKenna University of Florida
Ying Li
Ying Li Texas A&M University
Fabrizio Carta
Fabrizio Carta University of Florence
Xian Chen
Xian Chen University of North Carolina at Chapel Hill
James G. Ferry
James G. Ferry Pennsylvania State University
Claudiu T. Supuran
Claudiu T. Supuran University of Florence
Gregory A. Voth
Gregory A. Voth University of Chicago
Harry S. Nick
Harry S. Nick University of Florida

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