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Biology and Biochemistry

D-Index
82
Citations
134001
World Ranking
3596
National Ranking
1798

Overview

Hui Shen is a researcher affiliated with the Van Andel Institute in the United States. Their work predominantly spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a specific focus on Molecular Biology, Cancer Research, Oncology, Immunology, and Pulmonary and Respiratory Medicine.

The scientist's research addresses several main topics, including:

  • Epigenetics and DNA Methylation
  • Cancer Genomics and Diagnostics
  • RNA modifications and cancer
  • Single-cell and spatial transcriptomics
  • Cancer Immunotherapy and Biomarkers
  • Genomics and Chromatin Dynamics
  • DNA Repair Mechanisms

Hui Shen has contributed extensively to the academic literature, with numerous publications appearing in journals such as bioRxiv (Cold Spring Harbor Laboratory), UNC Libraries, Cancer Research, Cancer Cell, and Nature Communications.

Frequent co-authors collaborating with Hui Shen include:

  • Peter W. Laird
  • Wanding Zhou
  • Toshinori Hinoue
  • Benjamin K. Johnson
  • Ian Beddows

Notable recent papers by Hui Shen include:

  • Comprehensive Analysis of Genetic Ancestry and Its Molecular Correlates in Cancer, 2020, Cancer Cell
  • Phase II clinical trial of metformin as a cancer stem cell-targeting agent in ovarian cancer, 2020, JCI Insight
  • DNA methylation dynamics and dysregulation delineated by high-throughput profiling in the mouse, 2022, Cell Genomics
  • Multiomics in primary and metastatic breast tumors from the AURORA US network finds microenvironment and epigenetic drivers of metastasis, 2022, Nature Cancer
  • Molecular Features of Cancers Exhibiting Exceptional Responses to Treatment, 2020, Cancer Cell

Best Publications

  • Comprehensive molecular portraits of human breast tumours

    Daniel C. Koboldt;Robert S. Fulton;Michael D. McLellan;Heather Schmidt

  • The cancer genome atlas pan-cancer analysis project

    John N Weinstein;John N Weinstein;Eric A. Collisson;Gordon B Mills;Kenna R Mills Shaw;Kenna R Mills Shaw

  • Comprehensive molecular characterization of human colon and rectal cancer

    Donna M. Muzny;Matthew N. Bainbridge;Kyle Chang;Huyen H. Dinh

  • Inferring tumour purity and stromal and immune cell admixture from expression data

    Kosuke Yoshihara;Maria Shahmoradgoli;Emmanuel Martínez;Rahulsimham Vegesna

  • Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia

    Timothy J. Ley;Christopher Miller;Li Ding;Benjamin J. Raphael

  • Comprehensive molecular characterization of gastric adenocarcinoma

    Adam J. Bass;Vesteinn Thorsson;Ilya Shmulevich;Sheila M. Reynolds

  • Integrated genomic characterization of endometrial carcinoma

    Gad Getz;Stacey B. Gabriel;Kristian Cibulskis;Eric Lander

  • The Immune Landscape of Cancer

    Vésteinn Thorsson;David L Gibbs;Scott D Brown;Denise Wolf

  • Comprehensive molecular characterization of urothelial bladder carcinoma

    John N Weinstein;Rehan Akbani;Bradley McIntosh Broom;Wenyi Wang

  • Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.

    Daniel J. Brat;Roel G.W. Verhaak;Kenneth D. Aldape;W. K.Alfred Yung

  • Oncogenic Signaling Pathways in The Cancer Genome Atlas

    Francisco Sanchez-Vega;Marco Mina;Joshua Armenia;Walid K. Chatila

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • The Molecular Taxonomy of Primary Prostate Cancer

    Adam Abeshouse;Jaeil Ahn;Rehan Akbani;Adrian Ally

  • Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma.

    Houtan Noushmehr;Daniel J. Weisenberger;Kristin Diefes;Heidi S. Phillips

  • Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

    Katherine A. Hoadley;Christina Yau;Christina Yau;Toshinori Hinoue;Denise M. Wolf

  • Comprehensive Characterization of Cancer Driver Genes and Mutations.

    Matthew H Bailey;Collin Tokheim;Eduard Porta-Pardo;Sohini Sengupta

  • Absolute quantification of somatic DNA alterations in human cancer

    Scott L Carter;Kristian Cibulskis;Elena Helman;Elena Helman;Aaron McKenna

  • The Cancer Genome Atlas Pan-Cancer analysis project

    Kyle Chang;Chad J Creighton;Caleb Davis;Lawrence Donehower

  • The Molecular Taxonomy of Primary Prostate Cancer

    Adam Abeshouse;Jaeil Ahn;Rehan Akbani;Adrian Ally

  • Integrated genomic analyses of ovarian carcinoma

    D. Bell;A. Berchuck;M. Birrer;J. Chien

Frequent Co-Authors

Peter W. Laird
Peter W. Laird Van Andel Institute
Andrew D. Cherniack
Andrew D. Cherniack Broad Institute
Rameen Beroukhim
Rameen Beroukhim Harvard University
Daniel J. Weisenberger
Daniel J. Weisenberger University of Southern California
Matthew Meyerson
Matthew Meyerson Harvard University
Gad Getz
Gad Getz Broad Institute
John N. Weinstein
John N. Weinstein The University of Texas MD Anderson Cancer Center
Gordon B. Mills
Gordon B. Mills Oregon Health & Science University
Julie M. Gastier-Foster
Julie M. Gastier-Foster Baylor College of Medicine
Katherine A. Hoadley
Katherine A. Hoadley University of North Carolina at Chapel Hill

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