Transcription factor, Cell biology, Molecular biology, Binding site and PAX5 Transcription Factor are his primary areas of study. His work deals with themes such as Regulation of gene expression, Cancer research and DNA demethylation, which intersect with Transcription factor. His study in Cell biology is interdisciplinary in nature, drawing from both Genetics, Proto-Oncogene Proteins c-ets and Interleukin 15.
His Molecular biology research incorporates themes from Gene and DNA-binding protein. His studies in Binding site integrate themes in fields like HMG-box and DNA binding site. His PAX5 Transcription Factor study incorporates themes from Gene expression and Transcription.
The scientist’s investigation covers issues in Transcription factor, Cell biology, B cell, Molecular biology and Gene. The Transcription factor study combines topics in areas such as Regulation of gene expression and Transcription. He combines subjects such as Chromatin, Proto-Oncogene Proteins c-ets and Cell type with his study of Cell biology.
His work in B cell addresses issues such as Antigen, which are connected to fields such as breakpoint cluster region. His work carried out in the field of Molecular biology brings together such families of science as Gene rearrangement, Cellular differentiation, Promoter, PAX5 Transcription Factor and Binding site. The study incorporates disciplines such as T cell and Antibody in addition to Gene.
James Hagman mainly investigates Cell biology, Transcription factor, Gene, Chromatin and Hematopoietic stem cell. His Cell biology research integrates issues from RNA splicing, SR protein, Antigen and B cell. His B cell study combines topics from a wide range of disciplines, such as Alternative splicing, Reporter gene, Conditional gene knockout and Ectopic expression.
Transcription factor is a subfield of Genetics that James Hagman studies. His Interferon regulatory factors, IRF4 and Transcription study in the realm of Gene interacts with subjects such as Extramural. His Hematopoietic stem cell research includes themes of RNA, Ribosome, Cancer research and Bone marrow.
James Hagman spends much of his time researching Transcription factor, Histone, Biochemistry, Cell biology and Missense mutation. James Hagman has researched Transcription factor in several fields, including Mast cell and Transcription. In the subject of general Histone, his work in Nucleosome is often linked to Arginine and Proteolysis, thereby combining diverse domains of study.
His Cell biology research includes elements of IRF4, Gene, Bioinformatics and Interferon regulatory factors. His research in Missense mutation intersects with topics in Mutant and Intellectual disability. James Hagman integrates many fields in his works, including Genetics and Cerebellar ataxia.
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Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor.
Nikhil S. Joshi;Weiguo Cui;Anmol Chandele;Heung Kyu Lee.
Ets transcription factors: nuclear effectors of the Ras–MAP-kinase signaling pathway
Bohdan Wasylyk;James Hagman;Arthur Gutierrez-Hartmann.
Trends in Biochemical Sciences (1998)
A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate
Yin C Lin;Suchit Jhunjhunwala;Christopher Benner;Sven Heinz.
Nature Immunology (2010)
Structural Insights into Histone Demethylation by JMJD2 Family Members
Zhongzhou Chen;Jianye Zang;Johnathan Whetstine;Xia Hong.
Cloning and functional characterization of early B-cell factor, a regulator of lymphocyte-specific gene expression.
J Hagman;C Belanger;A Travis;C W Turck.
Genes & Development (1993)
Pax-5 (BSAP) recruits Ets proto-oncogene family proteins to form functional ternary complexes on a B-cell-specific promoter.
Daniel Fitzsimmons;W Hodsdon;W Wheat;S M Maira.
Genes & Development (1996)
Structural studies of Ets-1/Pax5 complex formation on DNA.
Colin W Garvie;James Hagman;Cynthia Wolberger.
Molecular Cell (2001)
Early B cell factor cooperates with Runx1 and mediates epigenetic changes associated with mb-1 transcription.
Holly Maier;Rachel Ostraat;Hua Gao;Scott Fields.
Nature Immunology (2004)
An inhibitory carboxyl-terminal domain in Ets-1 and Ets-2 mediates differential binding of ETS family factors to promoter sequences of the mb-1 gene
James Hagman;Rudolf Grosschedl.
Proceedings of the National Academy of Sciences of the United States of America (1992)
EBF contains a novel zinc coordination motif and multiple dimerization and transcriptional activation domains.
J. Hagman;M. J. Gutch;Haishan Lin;R. Grosschedl.
The EMBO Journal (1995)
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