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Medicine

D-Index
92
Citations
30585
World Ranking
11320
National Ranking
5810

Research.com Recognitions

  • 2012 - Fellow of the American Association for the Advancement of Science (AAAS)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

G. David Roodman is affiliated with Indiana University in the United States. Their research spans the field of Medicine, with a primary focus on Oncology and Hematology, as well as related areas such as Molecular Biology, Radiology, Nuclear Medicine and Imaging, and Genetics.

The scientist's main research topics encompass:

  • Multiple Myeloma Research and Treatments
  • Bone health and treatments
  • Peptidase Inhibition and Analysis
  • CAR-T cell therapy research
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Sphingolipid Metabolism and Signaling
  • Ubiquitin and proteasome pathways

G. David Roodman has contributed to several scientific papers, including:

  • Notch3 signaling between myeloma cells and osteocytes in the tumor niche promotes tumor growth and bone destruction (2022), published in Neoplasia
  • GFI1-Dependent Repression of SGPP1 Increases Multiple Myeloma Cell Survival (2022), published in Cancers
  • Mapping the High-Risk Multiple Myeloma Cell Surface Proteome Identifies T-Cell Inhibitory Receptors for Immune Targeting (2021), published in Blood
  • A novel CCL3-HMGB1 signaling axis regulating osteocyte RANKL expression in multiple myeloma (2024), published in Haematologica
  • Osteocytes and Paget's Disease of Bone (2024), published in Current Osteoporosis Reports

The frequent co-authors in their works include Jesús Delgado-Calle, Hayley M. Sabol, Cody Ashby, Noriyoshi Kurihara, and Teresita Bellido.

The main venues for their publications feature journals such as Neoplasia, Cancers, Haematologica, Blood, and Current Osteoporosis Reports.

G. David Roodman has been recognized as a Fellow of the American Association for the Advancement of Science (AAAS) since 2012 and is a member of the Association of American Physicians.

Best Publications

  • Mechanisms of bone metastasis.

    G. David Roodman

  • Primer on the metabolic bone diseases and disorders of mineral metabolism

    John P. Bilezikian;Roger Bouillon;Thomas Clemens;Juliet Compston

  • Osteoclast-like cell formation and its regulation by osteotropic hormones in mouse bone marrow cultures.

    N Takahashi;H Yamana;S Yoshiki;G D Roodman

  • Cell biology of the osteoclast.

    G.David Roodman

  • Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)-dependent migration and homing in multiple myeloma.

    Yazan Alsayed;Hai Ngo;Judith Runnels;Xavier Leleu

  • Pathogenesis of myeloma bone disease

    G. David Roodman;G. David Roodman

  • Macrophage inflammatory protein 1-alpha is a potential osteoclast stimulatory factor in multiple myeloma

    Sun Jin Choi;Jose C. Cruz;Fiona Craig;Hoyeon Chung

  • Biology of osteoclast activation in cancer.

    G. David Roodman

  • International Myeloma Working Group Recommendations for the Treatment of Multiple Myeloma–Related Bone Disease

    Evangelos Terpos;Gareth Morgan;Meletios Athanasios Dimopoulos;Matthew T. Drake

  • Denosumab versus zoledronic acid in bone disease treatment of newly diagnosed multiple myeloma: an international, double-blind, double-dummy, randomised, controlled, phase 3 study

    Noopur Raje;Evangelos Terpos;Wolfgang Willenbacher;Kazuyuki Shimizu

  • Transforming growth factor beta inhibits formation of osteoclast-like cells in long-term human marrow cultures

    C Chenu;J Pfeilschifter;G R Mundy;G D Roodman

  • Role of Magnetic Resonance Imaging in the Management of Patients With Multiple Myeloma: A Consensus Statement

    Meletios A. Dimopoulos;Jens Hillengass;Saad Usmani;Elena Zamagni

  • Paget disease of bone

    G. David Roodman;Jolene J. Windle

  • Multiple myeloma bone disease: Pathophysiology of osteoblast inhibition.

    Nicola Giuliani;Nicola Giuliani;Vittorio Rizzoli;Vittorio Rizzoli;G. David Roodman;G. David Roodman

  • Macrophage inflammatory protein-1α is an osteoclastogenic factor in myeloma that is independent of receptor activator of nuclear factor κB ligand

    Je-Ho Han;Sun Jin Choi;Noriyoshi Kurihara;Masanori Koide

  • 1,25-Dihydroxyvitamin D3 causes formation of multinucleated cells with several osteoclast characteristics in cultures of primate marrow.

    G D Roodman;K J Ibbotson;B R MacDonald;T J Kuehl

  • Intracellular fragmentation of bone resorption products by reactive oxygen species generated by osteoclastic tartrate-resistant acid phosphatase.

    Jussi M. Halleen;Seija Räisänen;Jari J. Salo;Sakamuri V. Reddy

  • Excess TGF-β mediates muscle weakness associated with bone metastases in mice

    David L Waning;Khalid S Mohammad;Steven Reiken;Wenjun Xie

  • Antisense inhibition of macrophage inflammatory protein 1-α blocks bone destruction in a model of myeloma bone disease

    Sun Jin Choi;Yasuo Oba;Yair Gazitt;Melissa Alsina

  • Interleukin-6 enhances hypercalcemia and bone resorption mediated by parathyroid hormone-related protein in vivo.

    J de la Mata;H L Uy;T A Guise;B Story

Frequent Co-Authors

Irene M. Ghobrial
Irene M. Ghobrial Harvard University
Teresita Bellido
Teresita Bellido University of Arkansas for Medical Sciences
Noopur Raje
Noopur Raje Harvard University
Guozhi Xiao
Guozhi Xiao Southern University of Science and Technology
David W. Dempster
David W. Dempster Columbia University
Evangelos Terpos
Evangelos Terpos National and Kapodistrian University of Athens
Michael P. Whyte
Michael P. Whyte Washington University in St. Louis
Allan Lipton
Allan Lipton Penn State Milton S. Hershey Medical Center
Matthew R. Smith
Matthew R. Smith Harvard University
Robin J. Leach
Robin J. Leach The University of Texas Health Science Center at San Antonio

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