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Socrates J. Tzartos

Socrates J. Tzartos

D-Index & Metrics

Immunology

D-Index
64
Citations
16110
World Ranking
2921
National Ranking
125

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Socrates J. Tzartos is affiliated with the Institut Pasteur in France, with a research focus spanning Medicine and Biochemistry, Genetics and Molecular Biology. Their work predominantly covers subfields such as Neurology, Molecular Biology, Genetics, Pathology and Forensic Medicine, and Computational Theory and Mathematics.

The main topics of their research include:

  • Nicotinic Acetylcholine Receptors Study
  • Myasthenia Gravis and Thymoma
  • Peripheral Neuropathies and Disorders
  • Receptor Mechanisms and Signaling
  • Autoimmune Neurological Disorders and Treatments
  • Computational Drug Discovery Methods
  • Ion channel regulation and function

The scientist has published extensively, with notable recent papers including:

  • "Autoantibody Specificities in Myasthenia Gravis; Implications for Improved Diagnostics and Therapeutics" (2020), Frontiers in Immunology
  • "Nicotinic Cholinergic System and COVID-19: In Silico Identification of an Interaction between SARS-CoV-2 and Nicotinic Receptors with Potential Therapeutic Targeting Implications" (2020), International Journal of Molecular Sciences
  • "Myasthenia Gravis: Autoantibody Specificities and Their Role in MG Management" (2020), Frontiers in Neurology
  • "Nicotinic cholinergic system and COVID-19: In silico evaluation of nicotinic acetylcholine receptor agonists as potential therapeutic interventions" (2020), Toxicology Reports
  • "Nicotinic cholinergic system and COVID-19: In silico identification of interactions between α7 nicotinic acetylcholine receptor and the cryptic epitopes of SARS-Co-V and SARS-CoV-2 Spike glycoproteins" (2021), Food and Chemical Toxicology

Frequent co-authors in their research include:

  • John S. Tzartos
  • Konstantinos Poulas
  • Erdem Tüzün
  • Sotirios Giannopoulos
  • Georgios Tsivgoulis

Their publications are often featured in journals such as:

  • Frontiers in Immunology
  • International Journal of Molecular Sciences
  • Preprints.org
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Alzheimer's & Dementia

The scientist is recognized as a member of the European Molecular Biology Organization (EMBO).

Best Publications

  • Monoclonal antibodies used to probe acetylcholine receptor structure: localization of the main immunogenic region and detection of similarities between subunits.

    Socrates J. Tzartos;Jon M. Lindstrom

  • Mapping of surface structures of electrophorus acetylcholine receptor using monoclonal antibodies.

    S J Tzartos;D E Rand;B L Einarson;J M Lindstrom

  • Specificities of antibodies to acetylcholine receptors in sera from myasthenia gravis patients measured by monoclonal antibodies

    Socrates J. Tzartos;Marjorie E. Seybold;Jon M. Lindstrom

  • Muscle and neuronal nicotinic acetylcholine receptors

    Dimitra Kalamida;Konstantinos Poulas;Konstantinos Poulas;Vassiliki Avramopoulou;Efrosini Fostieri

  • Autoantibodies to Lipoprotein-Related Protein 4 in Patients With Double-Seronegative Myasthenia Gravis

    Bin Zhang;John S. Tzartos;Maria Belimezi;Samia Ragheb

  • Myasthenia gravis — autoantibody characteristics and their implications for therapy

    Nils Erik Gilhus;Geir Olve Skeie;Geir Olve Skeie;Fredrik Romi;Fredrik Romi;Konstantinos Lazaridis

  • Production and assay of antibodies to acetylcholine receptors.

    Jon Lindstrom;Brett Einarson;Socrates Tzartos

  • A comprehensive analysis of the epidemiology and clinical characteristics of anti-LRP4 in myasthenia gravis

    P. Zisimopoulou;P. Evangelakou;J. Tzartos;K. Lazaridis

  • Localization of the main immunogenic region of human muscle acetylcholine receptor to residues 67-76 of the alpha subunit.

    Socrates J. Tzartos;Anna Kokla;Susan L. Walgrave;Bianca M. Conti-Tronconi

  • Anatomy of the antigenic structure of a large membrane autoantigen, the muscle-type nicotinic acetylcholine receptor.

    Socrates J. Tzartos;Tom Barkas;M. Thong Cung;Avgi Mamalaki

  • Nicotinic receptor subtypes in human brain ageing, Alzheimer and Lewy body diseases.

    Elaine Perry;Carmen Martin-Ruiz;Mandy Lee;Martin Griffiths

  • Autoantibody Specificities in Myasthenia Gravis; Implications for Improved Diagnostics and Therapeutics.

    Konstantinos Lazaridis;Socrates J. Tzartos

  • Inhibition of glycosylation with tunicamycin blocks assembly of newly synthesized acetylcholine receptor subunits in muscle cells.

    J P Merlie;R Sebbane;S Tzartos;J Lindstrom

  • Passive transfer of experimental autoimmune myasthenia gravis by monoclonal antibodies to the main immunogenic region of the acetylcholine receptor

    Socrates Tzartos;Susan Hochschwender;Peter Vasquez;Jon Lindstrom

  • Monoclonal antibodies as probes of acetylcholine receptor structure. 2. Binding to native receptor

    Bianca Conti-Tronconi;Socrates Tzartos;Jon Lindstrom

  • α4 but Not α3 and α7 Nicotinic Acetylcholine Receptor Subunits Are Lost from the Temporal Cortex in Alzheimer's Disease

    C. M. Martin‐Ruiz;J. A. Court;E. Molnar;M. Lee

  • Expression of acetylcholine receptor genes in human thymic epithelial cells: implications for myasthenia gravis

    A Wakkach;T Guyon;C Bruand;S Tzartos

  • Demonstration of a main immunogenic region on acetylcholine receptors from human muscle using monoclonal antibodies to human receptor.

    Socrates Tzartos;Lorene Langeberg;Susan Hochschwender;Jon Lindstrom

  • Characteristics of monoclonal antibodies to denatured Torpedo and to native calf acetylcholine receptors: Species, subunit and region specificity

    Socrates Tzartos;Socrates Tzartos;Lorene Langeberg;Susan Hochschwender;Larry W. Swanson

  • Pathogenesis of myasthenia gravis. Acetylcholine receptor-related antigenic determinants in tumor-free thymuses and thymic epithelial tumors.

    T Kirchner;S Tzartos;F Hoppe;B Schalke

  • Monoclonal antibodies used to probe acetylcholine receptor structure: Localization of the main immunogenic region and detection of similarities between subunits (interspecies crossreaction/muscle/experimental autoimmune myasthenia gravis)

    Socrates J. Tzartos;Jon M. Lindstrom

Frequent Co-Authors

Michel Marraud
Michel Marraud Centre national de la recherche scientifique, CNRS
Hans-Konrad Müller-Hermelink
Hans-Konrad Müller-Hermelink University of Würzburg
Sonia Berrih-Aknin
Sonia Berrih-Aknin Université Paris Cité
Jon Lindstrom
Jon Lindstrom University of Pennsylvania
Nils Erik Gilhus
Nils Erik Gilhus Haukeland University Hospital
Renato Mantegazza
Renato Mantegazza Istituto Neurologico Carlo Besta
Angela Vincent
Angela Vincent University of Oxford
David Beeson
David Beeson University of Oxford
Peter C. M. Molenaar
Peter C. M. Molenaar Pennsylvania State University
Lin Mei
Lin Mei Case Western Reserve University

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