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Neuroscience

D-Index
70
Citations
19020
World Ranking
2501
National Ranking
1187

Overview

Richard J. Smeyne is affiliated with Thomas Jefferson University in the United States and has contributed extensively to research in the fields of neuroscience and medicine. Their work primarily focuses on areas within neurology and cellular and molecular neuroscience, with additional contributions in clinical psychology, molecular biology, and infectious diseases.

The researcher's main topics of study include:

  • Neuroinflammation and Neurodegeneration Mechanisms
  • Parkinson's Disease Mechanisms and Treatments
  • Long-Term Effects of COVID-19
  • COVID-19 and Mental Health
  • Nuclear Receptors and Signaling
  • Nerve Injury and Regeneration
  • RNA Regulation and Disease

Richard J. Smeyne has authored several scientific papers. Recent publications include:

  • "COVID-19 and possible links with Parkinson's disease and parkinsonism: from bench to bedside," 2020, published in npj Parkinson s Disease
  • "Infection and Risk of Parkinson's Disease," 2020, published in Journal of Parkinson s Disease
  • "Rotenone induces regionally distinct α-synuclein protein aggregation and activation of glia prior to loss of dopaminergic neurons in C57Bl/6 mice," 2022, published in Neurobiology of Disease
  • "Alzheimer's disease-associated U1 snRNP splicing dysfunction causes neuronal hyperexcitability and cognitive impairment," 2022, published in Nature Aging
  • "Microglia-specific knock-out of NF-κB/IKK2 increases the accumulation of misfolded α-synuclein through the inhibition of p62/sequestosome-1-dependent autophagy in the rotenone model of Parkinson's disease," 2023, published in Glia

Their frequent co-authors include Matthew Byrne, Debotri Chatterjee, Ronald B. Tjalkens, Savannah M. Rocha, and Collin M. Bantle.

Publications by Richard J. Smeyne appear predominantly in venues such as:

  • npj Parkinson s Disease
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Parkinson s Disease
  • Neurobiology of Disease
  • Nature Aging

Best Publications

  • Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene

    Richard J. Smeyne;Rüdiger Klein;Andreas Schnapp;Linda K. Long

  • Continuous c-fos expression precedes programmed cell death in vivo

    Richard J. Smeyne;Montserrat Vendrell;Michael Hayward;Michael Hayward;Suzanne J. Baker

  • Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death

    Rüdiger Klein;Richard J. Smeyne;Wolfgang Wurst;Linda K. Long

  • Disruption of the neurotrophin-3 receptor gene trkC eliminates la muscle afferents and results in abnormal movements

    Rüdiger Klein;Inmaculada Silos-Santiago;Richard J. Smeyne;Sergio A. Lira

  • Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease : Critical role for the astrocyte

    Pei Chun Chen;Marcelo R. Vargas;Amar K. Pani;Richard J. Smeyne

  • The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice

    Steven Xanthoudakis;Richard J. Smeyne;James D. Wallace;Tom Curran

  • Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease

    Chang Hyuk Kwon;Xiaoyan Zhu;Junyuan Zhang;Lori L. Knoop

  • Highly pathogenic H5N1 influenza virus can enter the central nervous system and induce neuroinflammation and neurodegeneration

    Haeman Jang;David Boltz;Katharine Sturm-Ramirez;Kennie R. Shepherd

  • Recessive resistance to thyroid hormone in mice lacking thyroid hormone receptor beta: evidence for tissue-specific modulation of receptor function.

    D Forrest;E Hanebuth;R J Smeyne;N Everds

  • The MPTP model of Parkinson's disease.

    Richard Jay Smeyne;Vernice Jackson-Lewis

  • Sonic hedgehog signaling is required for expansion of granule neuron precursors and patterning of the mouse cerebellum.

    Paula M. Lewis;Amel Gritli-Linde;Richard Smeyne;Andreas Kottmann

  • Extensive enteric nervous system abnormalities in mice transgenic for artificial chromosomes containing Parkinson disease-associated α-synuclein gene mutations precede central nervous system changes

    Yien-Ming Kuo;Zhishan Li;Yun Jiao;Nathalie Gaborit

  • Regulation of c-fos expression in transgenic mice requires multiple interdependent transcription control elements.

    Linda M Robertson;Tom K Kerppola;Montserrat Vendrell;Daniel Luk

  • A promoter that drives transgene expression in cerebellar Purkinje and retinal bipolar neurons

    John Oberdick;Richard J. Smeyne;Jeff R. Mann;Saul Zackson

  • Immunologic Privilege in the Central Nervous System and the Blood–Brain Barrier

    Leslie L Muldoon;Jorge I Alvarez;David J Begley;Ruben J Boado

  • Environmental enrichment in adulthood eliminates neuronal death in experimental Parkinsonism

    Ciaran J. Faherty;Kennie Raviie Shepherd;Anna Herasimtschuk;Richard J. Smeyne

  • Fos-IacZ transgenic mice: Mapping sites of gene induction in the central nervous system

    Richard J. Smeyne;Karl Schilling;Linda Robertson;Daniel Luk

  • Retroviral-Mediated Transfer of the Green Fluorescent Protein Gene Into Murine Hematopoietic Cells Facilitates Scoring and Selection of Transduced Progenitors In Vitro and Identification of Genetically Modified Cells In Vivo

    Derek A. Persons;James A. Allay;Esther R. Allay;Richard J. Smeyne

  • A Golgi-Cox morphological analysis of neuronal changes induced by environmental enrichment

    Ciaran J. Faherty;Dan Kerley;Dan Kerley;Richard Jay Smeyne

  • Development and death of external granular layer cells in the weaver mouse cerebellum: a quantitative study

    RJ Smeyne;D Goldowitz

Frequent Co-Authors

Dan Goldowitz
Dan Goldowitz University of British Columbia
Robert W. Williams
Robert W. Williams University of Tennessee Health Science Center
Michael J. Zigmond
Michael J. Zigmond University of Pittsburgh
Rüdiger Klein
Rüdiger Klein Max Planck Society
Lu Lu
Lu Lu University of Tennessee Health Science Center
Kathryn M. Albers
Kathryn M. Albers University of Pittsburgh
Ken E. Olson
Ken E. Olson Colorado State University
Roberta Diaz Brinton
Roberta Diaz Brinton University of Arizona
Alexandra L. Joyner
Alexandra L. Joyner Memorial Sloan Kettering Cancer Center
Serge Przedborski
Serge Przedborski Columbia University

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