His primary scientific interests are in Immunology, Virology, Human leukocyte antigen, Genetics and Epitope. His Virus and Lentivirus study in the realm of Immunology connects with subjects such as Multivariate statistics. His work on Virology deals in particular with Viral replication, Viremia and Viral load.
In his study, Interferon and Group-specific antigen is strongly linked to Mutation, which falls under the umbrella field of Human leukocyte antigen. He combines subjects such as CTL* and Immune system with his study of Epitope. His research integrates issues of Peptide binding, Major histocompatibility complex and Histocompatibility in his study of Single-nucleotide polymorphism.
Chanson J. Brumme focuses on Virology, Immunology, Human leukocyte antigen, Viral load and Genetics. His Virology research incorporates elements of Epitope and Viral evolution. His Immunology research is mostly focused on the topic Lentivirus.
His Human leukocyte antigen research includes themes of Immune system, Antibody, CTL* and Allele. His Viral load research is multidisciplinary, relying on both Tropism, Internal medicine and Trofile assay. His work deals with themes such as Chronic infection and Reverse transcriptase, which intersect with Virus.
Chanson J. Brumme mainly investigates Virology, Severe acute respiratory syndrome coronavirus 2, Computational biology, Internal medicine and Proviral dna. His Virology research incorporates themes from Mutation, Human leukocyte antigen and Downregulation and upregulation. His studies deal with areas such as Viral evolution, Nonsynonymous substitution, Immune system, Viral entry and Infectivity as well as Human leukocyte antigen.
His research in Computational biology intersects with topics in Reverse transcriptase, Drug resistance and DNA sequencing. His study in Internal medicine is interdisciplinary in nature, drawing from both Nucleic acid, Oncology and Human dna. His work in Proviral dna addresses issues such as Digital polymerase chain reaction, which are connected to fields such as Viral load and Viral genetics.
His primary areas of investigation include Drug resistance, Severe acute respiratory syndrome coronavirus 2, Virology, Performance comparison and Quality assurance. His Drug resistance research integrates issues from Illumina miseq, Sequence comparison, Concordance, Genotyping and Sanger sequencing. 2019-20 coronavirus outbreak, Internal medicine, False Negative Reactions and Viral load are fields of study that intersect with his Severe acute respiratory syndrome coronavirus 2 research.
His Internal medicine research is multidisciplinary, incorporating perspectives in Digital polymerase chain reaction, Nucleic acid and Molecular marker. Chanson J. Brumme is interested in Infectivity, which is a field of Virology. His Downregulation and upregulation study combines topics from a wide range of disciplines, such as Tetherin, Clone, Mutagenesis, Viral pathogenesis and Viral protein.
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The major genetic determinants of HIV-1 control affect HLA class I peptide presentation
Pereyra F;Jia X;McLaren Pj.
Science (2010)
Predictors of HIV Drug-Resistance Mutations in a Large Antiretroviral-Naive Cohort Initiating Triple Antiretroviral Therapy
P. Richard Harrigan;Robert S. Hogg;Winnie W. Y. Dong;Benita Yip.
The Journal of Infectious Diseases (2005)
Adaptation of HIV-1 to human leukocyte antigen class I
Y. Kawashima;K. Pfafferott;J. Frater;P. Matthews.
Nature (2009)
Whole genome deep sequencing of HIV-1 reveals the impact of early minor variants upon immune recognition during acute infection
Matthew R. Henn;Christian L. Boutwell;Patrick Charlebois;Niall J Lennon.
PLOS Pathogens (2012)
Molecular and Clinical Epidemiology of CXCR4-Using HIV-1 in a Large Population of Antiretroviral-Naive Individuals
Zabrina L. Brumme;Zabrina L. Brumme;James Goodrich;Howard B. Mayer;Chanson J. Brumme.
The Journal of Infectious Diseases (2005)
Influence of HLA-C Expression Level on HIV Control
Richard Apps;Richard Apps;Ying Qi;Ying Qi;Jonathan M. Carlson;Haoyan Chen;Haoyan Chen.
Science (2013)
Antigen Load and Viral Sequence Diversification Determine the Functional Profile of HIV-1–Specific CD8+ T Cells
Hendrik Streeck;Zabrina L Brumme;Michael P. Anastario;Kristin W Cohen.
PLOS Medicine (2008)
HLA-B57/B*5801 Human Immunodeficiency Virus Type 1 Elite Controllers Select for Rare Gag Variants Associated with Reduced Viral Replication Capacity and Strong Cytotoxic T-Lymphotye Recognition
Toshiyuki Miura;Toshiyuki Miura;Mark A. Brockman;Arne Schneidewind;Michael Lobritz.
Journal of Virology (2009)
Human Immunodeficiency Virus Type 1-Specific CD8+ T-Cell Responses during Primary Infection Are Major Determinants of the Viral Set Point and Loss of CD4+ T Cells
Hendrik Streeck;Jonathan S. Jolin;Ying Qi;Bader Yassine-Diab.
Journal of Virology (2009)
Evidence of Differential HLA Class I-Mediated Viral Evolution in Functional and Accessory/Regulatory Genes of HIV-1
Zabrina L Brumme;Zabrina L Brumme;Zabrina L Brumme;Chanson J Brumme;Chanson J Brumme;David Heckerman;Bette T Korber;Bette T Korber.
PLOS Pathogens (2007)
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