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Immunology

D-Index
48
Citations
9398
World Ranking
4419
National Ranking
381

Overview

Kristin Ladell is affiliated with Cardiff University in the United Kingdom. Their academic work mainly focuses on the fields of Immunology and Microbiology as well as Medicine, with a substantial number of publications contributing to these domains.

Their research spans various subfields including Immunology, Infectious Diseases, Epidemiology, Molecular Biology, and Oncology. Key topics of their scholarly work cover Immune Cell Function and Interaction, T-cell and B-cell Immunology, Immunotherapy and Immune Responses, COVID-19 Clinical Research Studies, Cytomegalovirus and herpesvirus research, SARS-CoV-2 and COVID-19 Research, and CAR-T cell therapy research.

Recent papers include:

  • Two subsets of stem-like CD8+ memory T cell progenitors with distinct fate commitments in humans (2020, Nature Immunology)
  • VDJdb in the pandemic era: a compendium of T cell receptors specific for SARS-CoV-2 (2022, Nature Methods)
  • CD4+ T Follicular Helper Cells in Human Tonsils and Blood Are Clonally Convergent but Divergent from Non-Tfh CD4+ Cells (2020, Cell Reports)
  • SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies (2022, eLife)
  • A population of proinflammatory T cells coexpresses αβ and γδ T cell receptors in mice and humans (2020, The Journal of Experimental Medicine)

Ladell has collaborated frequently with several researchers, including:

  • David A. Price (41 coauthored works)
  • Kelly L. Miners (27 coauthored works)
  • James E. McLaren (12 coauthored works)
  • Dmitriy M. Chudakov (11 coauthored works)
  • Sian Llewellyn-Lacey (10 coauthored works)

The publication venues where Ladell's research most commonly appears include:

  • bioRxiv (Cold Spring Harbor Laboratory) with 11 publications
  • Oxford Open Immunology with 4 publications
  • Cell Reports with 3 publications
  • eLife with 3 publications
  • Nature Immunology with 2 publications

Best Publications

  • Monoclonal TCR-redirected tumor cell killing

    Nathaniel Liddy;Giovanna Bossi;Katherine J. Adams;Anna Lissina

  • VDJdb: a curated database of T-cell receptor sequences with known antigen specificity

    Mikhail Shugay;Dmitriy V Bagaev;Ivan V Zvyagin;Renske M Vroomans

  • Induction of complete and molecular remissions in acute myeloid leukemia by Wilms’ tumor 1 antigen-targeted dendritic cell vaccination

    Viggo F. van Tendeloo;Ann Van de Velde;Ann van Driessche;Nathalie Cools

  • Two subsets of stem-like CD8+ memory T cell progenitors with distinct fate commitments in humans.

    Giovanni Galletti;Gabriele De Simone;Emilia M C Mazza;Simone Puccio

  • Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance.

    Martin S. Davey;Carrie R. Willcox;Stephen P. Joyce;Kristin Ladell

  • Islet-reactive CD8+ T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors

    Slobodan Culina;Slobodan Culina;Slobodan Culina;Ana Ines Lalanne;Ana Ines Lalanne;Ana Ines Lalanne;Georgia Afonso;Georgia Afonso;Georgia Afonso;Karen Cerosaletti

  • VDJdb in the pandemic era: a compendium of T cell receptors specific for SARS-CoV-2

    Unknown

  • Dendritic cell vaccination as postremission treatment to prevent or delay relapse in acute myeloid leukemia

    Sébastien Anguille;Ann L. Van De Velde;Evelien L. Smits;Viggo F. Van Tendeloo

  • MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage

    Marielle C. Gold;James E. McLaren;Joseph A. Reistetter;Sue Smyk-Pearson

  • Memory CD4(+) T cells are generated in the human fetal intestine

    Na Li;Vincent van Unen;Tamim Abdelaal;Tamim Abdelaal;Nannan Guo

  • A recombinant modified vaccinia Ankara vaccine encoding Epstein-Barr virus (EBV) target antigens: a phase I trial in UK patients with EBV-positive cancer

    Graham S. Taylor;Hui Jia;Kevin Harrington;Lip Wai Lee

  • Chronic Inflammation Permanently Reshapes Tissue-Resident Immunity in Celiac Disease.

    Toufic Mayassi;Kristin Ladell;Herman Gudjonson;James E. McLaren

  • TCR β-Chain Sharing in Human CD8+ T Cell Responses to Cytomegalovirus and EBV

    Vanessa Venturi;Hui Yee Chin;Tedi E. Asher;Kristin Ladell

  • Protein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramers.

    Anna Lissina;Kristin Ingrid Ladell;Ania Skowera;Ania Skowera;Mathew Clement

  • A T Cell-Inducing Influenza Vaccine for the Elderly: Safety and Immunogenicity of MVA-NP+M1 in Adults Aged over 50 Years

    Richard D. Antrobus;Patrick J. Lillie;Tamara K. Berthoud;Alexandra J. Spencer

  • T cell receptor binding affinity governs the functional profile of cancer-specific CD8+ T cells.

    Mai Tan;A. B. Gerry;J. E. Brewer;L. Melchiori

  • A Molecular Basis for the Control of Preimmune Escape Variants by HIV-Specific CD8(+) T Cells.

    Kristin Ingrid Ladell;Masao Hashimoto;Maria Candela Iglesias;Pascal G. Wilmann

  • Modification of MHC Anchor Residues Generates Heteroclitic Peptides That Alter TCR Binding and T Cell Recognition

    David Cole;Emily Edwards;Katherine Wynn;Mathew Clement

  • Role of naïve-derived T memory stem cells in T-cell reconstitution following allogeneic transplantation

    Alessandra Roberto;Luca Castagna;Veronica Zanon;Stefania Bramanti

  • Highly prevalent colorectal cancer-infiltrating LAP⁺ Foxp3⁻ T cells exhibit more potent immunosuppressive activity than Foxp3⁺ regulatory T cells.

    Martin John Scurr;Kristin Ingrid Ladell;Matthieu Besneux;Adam Christian

  • β-Cell–Specific CD8 T Cell Phenotype in Type 1 Diabetes Reflects Chronic Autoantigen Exposure

    Ania Skowera;Kristin Ingrid Ladell;James Edward McLaren;Garry Michael Dolton

Frequent Co-Authors

David Price
David Price University of Aberdeen
Emma Gostick
Emma Gostick Cardiff University
John J. Miles
John J. Miles James Cook University
Andrew K. Sewell
Andrew K. Sewell Cardiff University
Jamie Rossjohn
Jamie Rossjohn Monash University
Andrew James Godkin
Andrew James Godkin Cardiff University
Dmitriy M. Chudakov
Dmitriy M. Chudakov Pirogov Russian National Research Medical University
Awen Gallimore
Awen Gallimore Cardiff University
Stephanie Gras
Stephanie Gras La Trobe University
Daniel C. Douek
Daniel C. Douek National Institute of Allergy and Infectious Diseases

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