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René A. W. van Lier

René A. W. van Lier

D-Index & Metrics

Immunology

D-Index
95
Citations
28016
World Ranking
914
National Ranking
31

Medicine

D-Index
95
Citations
28017
World Ranking
10181
National Ranking
402

Overview

René A. W. van Lier is affiliated with the University of Amsterdam in the Netherlands. Their research primarily focuses on immunology and microbiology as well as medicine, with particular emphasis on immunology, infectious diseases, epidemiology, neurology, and oncology.

The main topics covered in van Lier's work include:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Immunotherapy and Immune Responses
  • SARS-CoV-2 and COVID-19 Research
  • Cytomegalovirus and herpesvirus research
  • COVID-19 Clinical Research Studies
  • Long-Term Effects of COVID-19

Van Lier has contributed extensively to a variety of academic journals. The frequent publication venues featuring their research include:

  • European Journal of Immunology
  • Science Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Trials
  • Nature Immunology

Some of the recent papers authored involving van Lier are:

  • "Tissue-resident memory CD8+ T cells shape local and systemic secondary T cell responses," 2020, Nature Immunology
  • "Divergent SARS-CoV-2-specific T- and B-cell responses in severe but not mild COVID-19 patients," 2020, European Journal of Immunology
  • "Low SARS-CoV-2 seroprevalence in blood donors in the early COVID-19 epidemic in the Netherlands," 2020, Nature Communications
  • "Hobit identifies tissue-resident memory T cell precursors that are regulated by Eomes," 2021, Science Immunology
  • "Herd immunity is not a realistic exit strategy during a COVID-19 outbreak," 2020, Research Square (Research Square)

Van Lier frequently collaborates with several coauthors including:

  • Natasja A. M. Kragten
  • Klaas P. J. M. van Gisbergen
  • Pleun Hombrink
  • Matthieu Allez
  • Burkhard Becher

Best Publications

  • Phenotypic and Functional Separation of Memory and Effector Human CD8+ T Cells

    Dörte Hamann;Paul A. Baars;Martin H.G. Rep;Berend Hooibrink

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Mübeccel Akdis

  • Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes.

    Laura K. Mackay;Laura K. Mackay;Martina Minnich;Natasja A. M. Kragten;Yang Liao;Yang Liao

  • Phenotype and function of human T lymphocyte subsets: Consensus and issues

    Victor Appay;Rene A. W. van Lier;Federica Sallusto;Mario Roederer

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Andreas Acs

  • Primary immune responses to human CMV: a critical role for IFN-gamma-producing CD4+ T cells in protection against CMV disease.

    Laila E Gamadia;Ester B M Remmerswaal;Jan F Weel;Frederieke Bemelman

  • CD20 deficiency in humans results in impaired T cell–independent antibody responses

    Taco W. Kuijpers;Richard J. Bende;Paul A. Baars;Annette Grummels

  • Programs for the persistence, vigilance and control of human CD8 + lung-resident memory T cells

    Pleun Hombrink;Christina Helbig;Ronald A Backer;Berber Piet

  • Emergence of a CD4+CD28− Granzyme B+, Cytomegalovirus-Specific T Cell Subset after Recovery of Primary Cytomegalovirus Infection

    Ester M. M. van Leeuwen;Ester B. M. Remmerswaal;Mireille T. M. Vossen;Ajda T. Rowshani

  • Human CD8+ T-cell differentiation in response to viruses

    René A. W. van Lier;Ineke J. M. ten Berge;Laila E. Gamadia

  • Tissue-resident memory T cells populate the human brain

    Joost Smolders;Kirstin M. Heutinck;Nina L. Fransen;Ester B. M. Remmerswaal

  • Neutrophils Kill Antibody-Opsonized Cancer Cells by Trogoptosis.

    Hanke L Matlung;Liane Babes;Xi Wen Zhao;Michel van Houdt

  • Constitutive CD27/CD70 interaction induces expansion of effector-type T cells and results in IFNgamma-mediated B cell depletion.

    Ramon Arens;Kiki Tesselaar;Paul A Baars;Gijs M.W van Schijndel

  • Timing and tuning of CD27–CD70 interactions: the impact of signal strength in setting the balance between adaptive responses and immunopathology

    Martijn A. Nolte;Ronald W. van Olffen;Klaas P. J. M. van Gisbergen;René A. W. van Lier

  • Human NK cells can control CMV infection in the absence of T cells

    Taco W. Kuijpers;Paul A. Baars;Carole Dantin;Mirjam van den Burg

  • Lethal T cell immunodeficiency induced by chronic costimulation via CD27-CD70 interactions.

    Kiki Tesselaar;Ramon Arens;Gijs M.W. van Schijndel;Paul A. Baars

  • Tissue-resident memory T cells at the center of immunity to solid tumors.

    Derk Amsen;Klaas P. J. M. van Gisbergen;Pleun Hombrink;Rene A. W. van Lier

  • Faces and phases of human CD8+ T-cell development

    Dörte Hamann;Marijke Th.L Roos;René A.W van Lier

  • Reconstitution of the T-Cell Compartment After Bone Marrow Transplantation: Restoration of the Repertoire by Thymic Emigrants

    F Dumont-Girard;E Roux;R A van Lier;G Hale

  • Expression of the Murine CD27 Ligand CD70 In Vitro and In Vivo

    Kiki Tesselaar;Yanling Xiao;Ramon Arens;Gijs M. W. van Schijndel

  • Selective accumulation of differentiated CD8(+) T cells specific for respiratory viruses in the human lung

    Godelieve J. de Bree;Ester M.M. van Leeuwen;Theo A. Out;Henk M. Jansen

Frequent Co-Authors

Ineke J. M. ten Berge
Ineke J. M. ten Berge University of Amsterdam
Eric Eldering
Eric Eldering University of Amsterdam
Jörg Hamann
Jörg Hamann University of Amsterdam
Taco W. Kuijpers
Taco W. Kuijpers University of Amsterdam
Ramon Arens
Ramon Arens Leiden University Medical Center
Steven T. Pals
Steven T. Pals University of Amsterdam
Jannie Borst
Jannie Borst Leiden University Medical Center
Paul P. Tak
Paul P. Tak GlaxoSmithKline (United Kingdom)
Frank Baas
Frank Baas Leiden University Medical Center

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