The scientist’s investigation covers issues in Immunology, Cytotoxic T cell, Interleukin 21, Natural killer T cell and Antigen-presenting cell. His Virology research extends to Immunology, which is thematically connected. His research is interdisciplinary, bridging the disciplines of Cell biology and Cytotoxic T cell.
His study in Cell biology is interdisciplinary in nature, drawing from both Transcription factor and Lymphocyte. His studies examine the connections between Interleukin 21 and genetics, as well as such issues in Interleukin 12, with regards to Granzyme B. René A. W. van Lier combines subjects such as CD28 and Molecular biology with his study of IL-2 receptor.
His primary scientific interests are in Immunology, Cytotoxic T cell, CD8, Cell biology and T cell. His Immunology research incorporates themes from CD40 and Virology. His study in Interleukin 21, IL-2 receptor, Natural killer T cell and Antigen-presenting cell are all subfields of Cytotoxic T cell.
His Interleukin 21 research incorporates elements of Interleukin 12, Memory T cell and Cancer research. His work in the fields of Granzyme B overlaps with other areas such as Population. His Cell biology research integrates issues from Receptor, Transcription factor, Apoptosis and Cellular differentiation.
His primary areas of investigation include CD8, Immunology, Cell biology, Immune system and Cytotoxic T cell. His studies deal with areas such as Phenotype, T cell, Lung and Function as well as CD8. His work on Memory T cell and ZAP70 is typically connected to Persistence and Vigilance as part of general Immunology study, connecting several disciplines of science.
René A. W. van Lier has included themes like Natural killer T cell, Transcription factor, Antigen and T-cell receptor in his Cell biology study. His research investigates the connection between Cytotoxic T cell and topics such as Cellular differentiation that intersect with issues in Small intestine. René A. W. van Lier interconnects Molecular biology, Interleukin 21, IL-2 receptor and Antigen-presenting cell in the investigation of issues within Granzyme B.
His primary areas of study are Cell biology, Immune system, Transcription factor, CD8 and Flow cytometry. As a part of the same scientific family, René A. W. van Lier mostly works in the field of Cell biology, focusing on T-cell receptor and, on occasion, Transcriptome, Programmed cell death and Receptor. His Immune system study which covers Cancer research that intersects with Function, Immunity, Cancer and Lineage.
His work carried out in the field of Transcription factor brings together such families of science as Natural killer T cell, Transcription and Immunology, Effector. Specifically, his work in Immunology is concerned with the study of Lymphocyte. René A. W. van Lier works mostly in the field of CD8, limiting it down to concerns involving Chemokine receptor and, occasionally, Integrin.
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Phenotypic and Functional Separation of Memory and Effector Human CD8+ T Cells
Dörte Hamann;Paul A. Baars;Martin H.G. Rep;Berend Hooibrink.
Journal of Experimental Medicine (1997)
CD27 is required for generation and long-term maintenance of T cell immunity
Jenny Hendriks;Loes A. Gravestein;Kiki Tesselaar;René A. W. van Lier.
Nature Immunology (2000)
Phenotype and function of human T lymphocyte subsets: Consensus and issues
Victor Appay;Rene A. W. van Lier;Federica Sallusto;Mario Roederer.
Cytometry Part A (2008)
Primary immune responses to human CMV: a critical role for IFN-γ–producing CD4+ T cells in protection against CMV disease
Laila E Gamadia;Ester B M Remmerswaal;Jan F Weel;Frederieke Bemelman.
Blood (2003)
Guidelines for the use of flow cytometry and cell sorting in immunological studies
Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Mübeccel Akdis.
European Journal of Immunology (2017)
CD20 deficiency in humans results in impaired T cell–independent antibody responses
Taco W. Kuijpers;Richard J. Bende;Paul A. Baars;Annette Grummels.
Journal of Clinical Investigation (2010)
Human CD8+ T-cell differentiation in response to viruses
René A. W. van Lier;Ineke J. M. ten Berge;Laila E. Gamadia.
Nature Reviews Immunology (2003)
Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes.
Laura K. Mackay;Laura K. Mackay;Martina Minnich;Natasja A. M. Kragten;Yang Liao.
Science (2016)
Emergence of a CD4+CD28− Granzyme B+, Cytomegalovirus-Specific T Cell Subset after Recovery of Primary Cytomegalovirus Infection
Ester M. M. van Leeuwen;Ester B. M. Remmerswaal;Mireille T. M. Vossen;Ajda T. Rowshani.
Journal of Immunology (2004)
Constitutive CD27/CD70 interaction induces expansion of effector-type T cells and results in IFNgamma-mediated B cell depletion.
Ramon Arens;Kiki Tesselaar;Paul A Baars;Gijs M.W van Schijndel.
Immunity (2001)
University of Amsterdam
University of Amsterdam
University of Amsterdam
Leiden University Medical Center
University of Amsterdam
Leiden University Medical Center
GlaxoSmithKline (United Kingdom)
University of Amsterdam
Leiden University Medical Center
Antoni van Leeuwenhoek Hospital
Profile was last updated on December 6th, 2021.
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