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Chemistry

D-Index
47
Citations
7217
World Ranking
15726
National Ranking
574

Overview

Romana Fato is affiliated with the University of Bologna in Italy and contributes extensively to the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their research work heavily focuses on subfields such as Molecular Biology, Cancer Research, Clinical Biochemistry, Electrical and Electronic Engineering, and Biochemistry.

The scientist's research spans several prominent topics, including:

  • Coenzyme Q10 studies and effects
  • Mitochondrial Function and Pathology
  • Metabolism and Genetic Disorders
  • RNA modifications and cancer
  • Advanced battery technologies research
  • Reproductive tract infections research
  • Urinary Tract Infections Management

Romana Fato has contributed to academic literature through publications in various journals, with repeated contributions to specific venues. The most frequent publication outlets include:

  • International Journal of Molecular Sciences
  • Antioxidants
  • Microbial Pathogenesis
  • Preprints.org
  • Journal of Experimental & Clinical Cancer Research

Some of the recent papers authored or co-authored by Romana Fato are:

  • The Roles of Coenzyme Q in Disease: Direct and Indirect Involvement in Cellular Functions (2021, International Journal of Molecular Sciences)
  • Biallelic variants in LIG3 cause a novel mitochondrial neurogastrointestinal encephalomyopathy (2021, Brain)
  • Coenzyme Q10 Phytosome Formulation Improves CoQ10 Bioavailability and Mitochondrial Functionality in Cultured Cells (2021, Antioxidants)
  • MiR-494 induces metabolic changes through G6pc targeting and modulates sorafenib response in hepatocellular carcinoma (2023, Journal of Experimental & Clinical Cancer Research)
  • Coenzyme Q biosynthesis inhibition induces HIF-1α stabilization and metabolic switch toward glycolysis (2020, FEBS Journal)

Collaboration is an important aspect of Romana Fato's research activities. Frequent co-authors include:

  • Christian Bergamini
  • Nicola Rizzardi
  • Irene Liparulo
  • Francesca Valenti
  • Luca Pincigher

Through these collaborations and prolific publishing record, Romana Fato engages with topics at the intersection of cellular bioenergetics, mitochondrial dysfunction, metabolism, and cancer biology. This multidisciplinary approach also extends into areas such as advanced battery technologies and infectious diseases, reflecting a broad scope within biomedical and biotechnological research.

Best Publications

  • Role of mitochondria in oxidative stress and aging.

    Giorgio Lenaz;Carla Bovina;Marilena D'aurelio;Romana Fato

  • The role of DT-diaphorase in the maintenance of the reduced antioxidant form of coenzyme Q in membrane systems

    R E Beyer;J Segura-Aguilar;S Di Bernardo;M Cavazzoni

  • Differential effects of mitochondrial Complex I inhibitors on production of reactive oxygen species.

    Romana Fato;Christian Bergamini;Marco Bortolus;Anna Lisa Maniero

  • The role of Coenzyme Q in mitochondrial electron transport.

    Giorgio Lenaz;Romana Fato;Gabriella Formiggini;Maria Luisa Genova

  • Mitochondrial Complex I: structural and functional aspects.

    Giorgio Lenaz;Romana Fato;Maria Luisa Genova;Christian Bergamini

  • Assay conditions for the mitochondrial NADH:coenzyme Q oxidoreductase

    Ernesto Estornell;Romana Fato;Francesco Pallotti;Giorgio Lenaz

  • Dynamics of biological membranes.

    Lenaz G;Fato R;Baracca A;Solaini G

  • Determination of partition and lateral diffusion coefficients of ubiquinones by fluorescence quenching of n-(9-anthroyloxy)stearic acids in phospholipid vesicles and mitochondrial membranes.

    Fato R;Battino M;Degli Esposti M;Parenti Castelli G

  • Mitochondrial Complex I defects in aging

    Giorgio Lenaz;Carla Bovina;Cinzia Castelluccio;Romana Fato

  • Steady-state kinetics of the reduction of coenzyme Q analogs by complex I (NADH:ubiquinone oxidoreductase) in bovine heart mitochondria and submitochondrial particles.

    Fato R;Estornell E;Di Bernardo S;Pallotti F

  • Multitarget Drug Design Strategy: Quinone–Tacrine Hybrids Designed To Block Amyloid-β Aggregation and To Exert Anticholinesterase and Antioxidant Effects

    Eugenie Nepovimova;Elisa Uliassi;Jan Korabecny;Luis Emiliano Peña-Altamira

  • Novel Class of Quinone-Bearing Polyamines as Multi-Target-Directed Ligands To Combat Alzheimer's Disease

    Maria Laura Bolognesi;Rita Banzi;Manuela Bartolini;Andrea Cavalli

  • Mitochondrial respiratory chain super-complex I–III in physiology and pathology

    Giorgio Lenaz;Alessandra Baracca;Giovanna Barbero;Christian Bergamini

  • Isolation of mitochondria from cells and tissues.

    Pin-Chao Liao;Christian Bergamini;Romana Fato;Liza A. Pon

  • Versatility of the Curcumin Scaffold: Discovery of Potent and Balanced Dual BACE-1 and GSK-3β Inhibitors.

    Rita Maria Concetta Di Martino;Angela De Simone;Vincenza Andrisano;Paola Bisignano

  • Saturation kinetics of coenzyme Q in NADH and succinate oxidation in beef heart mitochondria.

    E. Estornell;R. Fato;C. Castelluccio;M. Cavazzoni

  • Complex I and complex III of mitochondria have common inhibitors acting as ubiquinone antagonists.

    M.D. Esposti;A. Ghelli;M. Crimi;E. Estornell

  • Localization and mobility of coenzyme Q in lipid bilayers and membranes.

    Giorgio Lenaz;Romana Fato;Salvatore Di Bernardo;Diana Jarreta

  • A Water Soluble CoQ10 Formulation Improves Intracellular Distribution and Promotes Mitochondrial Respiration in Cultured Cells

    Christian Bergamini;Noah Moruzzi;Antonella Sblendido;Giorgio Lenaz

  • Respiratory complex I is essential to induce a Warburg profile in mitochondria-defective tumor cells

    Claudia Calabrese;Luisa Iommarini;Ivana Kurelac;Maria Antonietta Calvaruso

  • Generation of Reactive Oxygen Species by Mitochondrial Complex I: Implications in Neurodegeneration

    Romana Fato;Christian Bergamini;Serena Leoni;Paola Strocchi

Frequent Co-Authors

Giorgio Lenaz
Giorgio Lenaz University of Bologna
Andrea Cavalli
Andrea Cavalli Italian Institute of Technology
Maria Laura Bolognesi
Maria Laura Bolognesi University of Bologna
Vincenza Andrisano
Vincenza Andrisano University of Bologna
Maurizio Battino
Maurizio Battino Marche Polytechnic University
Manuela Bartolini
Manuela Bartolini University of Bologna
Marcel Kaiser
Marcel Kaiser Swiss Tropical and Public Health Institute
Reto Brun
Reto Brun University of Basel
Hisanori Suzuki
Hisanori Suzuki University of Verona
Nereo Bresolin
Nereo Bresolin University of Milan

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