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Immunology

D-Index
64
Citations
26872
World Ranking
2886
National Ranking
1361

Overview

Donna L. Bratton is affiliated with the University of Colorado Anschutz Medical Campus in the United States. Their research primarily focuses on the field of Immunology and Microbiology, with 11 related publications.

The scientist's work covers various subfields including Immunology, Neurology, Molecular Biology, Surgery, and Pharmacology. Key topics addressed in their research include Neutrophil, Myeloperoxidase and Oxidative Mechanisms; Immune cells in cancer; Neuroinflammation and Neurodegeneration Mechanisms; Phagocytosis and Immune Regulation; Pancreatic function and diabetes; Cannabis and Cannabinoid Research; and Inflammasome and immune disorders.

Donna L. Bratton has contributed to multiple scientific papers in several journals and publication venues such as:

  • Cell Reports
  • Blood
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Immunology
  • The Journal of Immunology

Recent publications by this researcher include:

  • "Polyamine import and accumulation causes immunomodulation in macrophages engulfing apoptotic cells," 2022, Cell Reports
  • "Heightened turnover and failed maturation of monocyte-derived macrophages in murine chronic granulomatous disease," 2021, Blood
  • "Macrophage Xanthine Oxidoreductase Links LPS Induced Lung Inflammatory Injury to NLRP3 Inflammasome Expression and Mitochondrial Respiration," 2023, bioRxiv (Cold Spring Harbor Laboratory)
  • "TNFα: TNFR1 signaling inhibits maturation and maintains the pro-inflammatory programming of monocyte-derived macrophages in murine chronic granulomatous disease," 2024, Frontiers in Immunology
  • "Nox2 deficiency in neutrophils promotes excessive and sustained inflammatory responses at local and distal sites of inflammation," 2020, The Journal of Immunology

Donna L. Bratton frequently collaborates with several coauthors, including:

  • Peter M. Henson
  • Kara J. Mould
  • Sophie L. Gibbings
  • K. Haist
  • Alexandra L. McCubbrey

Best Publications

  • Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.

    Valerie A. Fadok;D L Bratton;A Konowal;P W Freed

  • A receptor for phosphatidylserine-specific clearance of apoptotic cells

    Valerie A. Fadok;Donna L. Bratton;David M. Rose;Alan Pearson

  • Cell-Surface Calreticulin Initiates Clearance of Viable or Apoptotic Cells through trans-Activation of LRP on the Phagocyte

    Shyra J. Gardai;Kathleen A. McPhillips;S. Courtney Frasch;William J. Janssen

  • C1q and Mannose Binding Lectin Engagement of Cell Surface Calreticulin and Cd91 Initiates Macropinocytosis and Uptake of Apoptotic Cells

    Carol Anne Ogden;Aimee deCathelineau;Peter R. Hoffmann;Donna Bratton

  • The role of phosphatidylserine in recognition of apoptotic cells by phagocytes.

    Valerie A. Fadok;Donna L. Bratton;S. Courtney Frasch;Mary L. Warner

  • Loss of Phospholipid Asymmetry and Surface Exposure of Phosphatidylserine Is Required for Phagocytosis of Apoptotic Cells by Macrophages and Fibroblasts

    Valerie A. Fadok;Aimee de Cathelineau;David L. Daleke;Peter M. Henson

  • Appearance of Phosphatidylserine on Apoptotic Cells Requires Calcium-mediated Nonspecific Flip-Flop and Is Enhanced by Loss of the Aminophospholipid Translocase

    Donna L. Bratton;Valerie A. Fadok;Donald A. Richter;Jenai M. Kailey

  • Apoptotic cell removal

    Peter M Henson;Donna L Bratton;Valerie A Fadok

  • Phosphatidylserine (PS) induces PS receptor–mediated macropinocytosis and promotes clearance of apoptotic cells

    Peter R. Hoffmann;Aimee M. deCathelineau;Carol Anne Ogden;Yann Leverrier

  • Phagocyte receptors for apoptotic cells: recognition, uptake, and consequences.

    Valerie A. Fadok;Donna L. Bratton;Peter M. Henson

  • Montelukast, a leukotriene receptor antagonist, for the treatment of persistent asthma in children aged 2 to 5 years.

    Barbara Knorr;Luis M. Franchi;Hans Bisgaard;Jan Hendrik Vermeulen

  • CD36 is required for phagocytosis of apoptotic cells by human macrophages that use either a phosphatidylserine receptor or the vitronectin receptor (alpha v beta 3).

    Valerie A. Fadok;Mary L. Warner;Donna L. Bratton;Peter M. Henson

  • Phosphorylation of Bax Ser184 by Akt regulates its activity and apoptosis in neutrophils

    Shyra J. Gardai;David A. Hildeman;Steve K. Frankel;Ben B. Whitlock

  • Elastase-mediated phosphatidylserine receptor cleavage impairs apoptotic cell clearance in cystic fibrosis and bronchiectasis

    R. William Vandivier;Valerie A. Fadok;Peter R. Hoffmann;Donna L. Bratton

  • Differential Effects of Apoptotic Versus Lysed Cells on Macrophage Production of Cytokines: Role of Proteases

    Valerie A. Fadok;Donna L. Bratton;Lindsay Guthrie;Peter M. Henson

  • Three Unique Interstitial Macrophages in the Murine Lung at Steady State

    Sophie L. Gibbings;Stacey M. Thomas;Shaikh M. Atif;Alexandra L. McCubbrey

  • The phosphatidylserine receptor: a crucial molecular switch?

    Peter M. Henson;Donna L. Bratton;Valerie A. Fadok

  • Targeting hypoxia signalling for the treatment of ischaemic and inflammatory diseases

    Holger K. Eltzschig;Donna L. Bratton;Sean P. Colgan

  • Neutrophil clearance: when the party is over, clean-up begins

    Donna L. Bratton;Peter M. Henson

  • Modulation of macrophage efferocytosis in inflammation.

    Darlynn R Korns;S. Courtney Frasch;Ruby Fernandez-Boyanapalli;Peter M Henson

  • Transcriptional and translational regulation of inflammatory mediator production by endogenous TGF-beta in macrophages that have ingested apoptotic cells.

    Patrick P. McDonald;Valerie A. Fadok;Donna Bratton;Peter M. Henson

Frequent Co-Authors

Peter M. Henson
Peter M. Henson National Jewish Health
Valerie A. Fadok
Valerie A. Fadok Zoetis (United States)
Robert C. Murphy
Robert C. Murphy University of Colorado Denver
David W. H. Riches
David W. H. Riches University of Colorado Denver
Claudia Jakubzick
Claudia Jakubzick Dartmouth College
Jerry A. Nick
Jerry A. Nick National Jewish Health
Erwin W. Gelfand
Erwin W. Gelfand University of Colorado Anschutz Medical Campus
Hong Wei Chu
Hong Wei Chu National Jewish Health
Christina S. Leslie
Christina S. Leslie Memorial Sloan Kettering Cancer Center
Niels Borregaard
Niels Borregaard University of Copenhagen

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