The scientist’s investigation covers issues in Angiogenesis, Cell biology, Endothelium, Angiopoietin and Angiopoietin receptor. His research integrates issues of Ex vivo, Vascular endothelial growth factor and Immunology in his study of Angiogenesis. His work deals with themes such as Vascular endothelial growth factor A, Vascular endothelial growth factor B, Endocrinology and Spheroid, which intersect with Cell biology.
He regularly links together related areas like Endothelial stem cell in his Endothelium studies. While the research belongs to areas of Angiopoietin, Hellmut G. Augustin spends his time largely on the problem of Autocrine signalling, intersecting his research to questions surrounding Proinflammatory cytokine, Leukocyte Rolling, Paracrine signalling and Weibel–Palade body. His study explores the link between Angiopoietin receptor and topics such as TIE1 that cross with problems in Signal transduction, Receptor tyrosine kinase, Biochemistry, Binding domain and Epidermal growth factor.
Hellmut G. Augustin focuses on Cell biology, Angiogenesis, Cancer research, Endothelial stem cell and Pathology. The Cell biology study combines topics in areas such as Vascular endothelial growth factor A, Endothelium, Angiopoietin receptor and Angiopoietin. His Angiopoietin receptor research is multidisciplinary, incorporating elements of Pericyte and TIE1.
The concepts of his Angiogenesis study are interwoven with issues in Vascular endothelial growth factor and Immunology. The Cancer research study combines topics in areas such as Tumor progression, Downregulation and upregulation, Metastasis and Liver regeneration. As a part of the same scientific family, Hellmut G. Augustin mostly works in the field of Endothelial stem cell, focusing on Endocrinology and, on occasion, Preeclampsia.
His primary areas of study are Cancer research, Angiogenesis, Metastasis, Cell biology and Angiopoietin. Hellmut G. Augustin interconnects Biomarker, Platelet, Steatohepatitis and Immunotherapy in the investigation of issues within Cancer research. His Angiogenesis research incorporates themes from Choroidal neovascularization, Vascular endothelial growth factor and Regeneration.
His work investigates the relationship between Metastasis and topics such as Tumor microenvironment that intersect with problems in Melanoma. His study on Progenitor cell is often connected to Caspase 8 as part of broader study in Cell biology. His Angiopoietin research incorporates elements of Lymphatic Endothelium, Function, Alternative splicing, Morphogenesis and Regulator.
His primary scientific interests are in Cancer research, Angiogenesis, Biomarker, Steatohepatitis and Cell biology. His study in Cancer research is interdisciplinary in nature, drawing from both Platelet aggregation inhibitor, Fatty liver, Platelet activation, Macrophage and In vivo. Hellmut G. Augustin combines subjects such as Choroidal neovascularization, Clinical significance, Primary tumor, Metastasis and Colorectal cancer with his study of Angiogenesis.
Hellmut G. Augustin has researched Biomarker in several fields, including Tumor necrosis factor alpha, T cell, CD8, Adjuvant and Hepatocellular carcinoma. His biological study spans a wide range of topics, including Steatosis, Platelet Glycoprotein GPIb-IX Complex, Liver cancer, Platelet and Immunotherapy. His work carried out in the field of Cell biology brings together such families of science as Endothelial stem cell, Peripheral blood and Smooth muscle.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Control of vascular morphogenesis and homeostasis through the angiopoietin–Tie system
Hellmut G. Augustin;Gou Young Koh;Gavin Thurston;Kari Alitalo.
Nature Reviews Molecular Cell Biology (2009)
Angiopoietin-2 sensitizes endothelial cells to TNF-alpha and has a crucial role in the induction of inflammation.
Ulrike Fiedler;Yvonne Reiss;Marion Scharpfenecker;Verena Grunow.
Nature Medicine (2006)
Heterogeneity of Angiogenesis and Blood Vessel Maturation in Human Tumors: Implications for Antiangiogenic Tumor Therapies
Anne Eberhard;Sebastian Kahlert;Valentin Goede;Bernhard Hemmerlein.
Cancer Research (2000)
A novel vascular endothelial growth factor encoded by Orf virus, VEGF‐E, mediates angiogenesis via signalling through VEGFR‐2 (KDR) but not VEGFR‐1 (Flt‐1) receptor tyrosine kinases
Marlene Meyer;Matthias Clauss;Albrecht Lepple-Wienhues;Johannes Waltenberger.
The EMBO Journal (1999)
The Tie-2 ligand angiopoietin-2 is stored in and rapidly released upon stimulation from endothelial cell Weibel-Palade bodies.
Ulrike Fiedler;Marion Scharpfenecker;Stefanie Koidl;Anja Hegen.
Angiopoietins: a link between angiogenesis and inflammation.
Ulrike Fiedler;Hellmut G. Augustin.
Trends in Immunology (2006)
Integration of endothelial cells in multicellular spheroids prevents apoptosis and induces differentiation
Thomas Korff;Hellmut G. Augustin.
Journal of Cell Biology (1998)
Tensional forces in fibrillar extracellular matrices control directional capillary sprouting
Thomas Korff;Hellmut G. Augustin.
Journal of Cell Science (1999)
Blood vessel maturation in a 3-dimensional spheroidal coculture model: direct contact with smooth muscle cells regulates endothelial cell quiescence and abrogates VEGF responsiveness
Thomas Korff;Sarah Kimmina;Georg Martiny-Baron;Hellmut G. Augustin.
The FASEB Journal (2001)
The role of the Angiopoietins in vascular morphogenesis
Markus Thomas;Markus Thomas;Hellmut G. Augustin;Hellmut G. Augustin.
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below: