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Biology and Biochemistry

D-Index
63
Citations
14908
World Ranking
10175
National Ranking
346

Overview

Markus Hecker is a researcher affiliated with Heidelberg University in Germany. Their work spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a significant focus on Molecular Biology and Cardiology and Cardiovascular Medicine. Additional subfields of study include Surgery, Cell Biology, and Immunology.

The scientist's research topics cover various areas related to cellular and cardiovascular functions. Key topics include:

  • Cell Adhesion Molecules Research
  • Cardiac Fibrosis and Remodeling
  • Tissue Engineering and Regenerative Medicine
  • Cellular Mechanics and Interactions
  • Cardiac electrophysiology and arrhythmias
  • Aldose Reductase and Taurine
  • Platelet Disorders and Treatments

Markus Hecker has a substantial number of publications in frequent venues such as:

  • Cells
  • Biochemical Pharmacology
  • Frontiers in Physiology
  • Cardiovascular Research
  • Basic Research in Cardiology

Among recent publications are several papers dating from 2021 to 2022, illustrating ongoing research interests in cardiovascular and molecular interventions:

  • Substrate Stiffness Influences Structural and Functional Remodeling in Induced Pluripotent Stem Cell-Derived Cardiomyocytes (2021) in Frontiers in Physiology
  • Alginate hydrogel polymers enable efficient delivery of a vascular-targeted AAV vector into aortic tissue (2021) in Molecular Therapy - Methods & Clinical Development
  • AAV-mediated AP-1 decoy oligonucleotide expression inhibits aortic elastolysis in a mouse model of Marfan syndrome (2021) in Cardiovascular Research
  • AAV-mediated expression of NFAT decoy oligonucleotides protects from cardiac hypertrophy and heart failure (2021) in Basic Research in Cardiology
  • Short-term rapamycin treatment increases life span and attenuates aortic aneurysm in a murine model of Marfan-Syndrome (2022) in Biochemical Pharmacology

The collaboration network of Markus Hecker includes frequent co-authors such as Andreas H. Wagner, Thomas Korff, Nina D. Ullrich, Jaafar Al-Hasani, and Marcin Zaradzki.

The scientist has contributed to book publications under Springer International Publishing, including:

  • Cardiac Mechanobiology in Physiology and Disease (2023)
  • Vascular Mechanobiology in Physiology and Disease (2021)

Best Publications

  • Endothelial Notch1 Activity Facilitates Metastasis

    Elfriede Wieland;Juan Rodriguez-Vita;Sven S. Liebler;Sven S. Liebler;Carolin Mogler

  • Origin of Hydroxylated Brominated Diphenyl Ethers: Natural Compounds or Man-Made Flame Retardants?

    Yi Wan;Steve Wiseman;Hong Chang;Xiaowei Zhang

  • Effect of perinatal and postnatal bisphenol A exposure to the regulatory circuits at the hypothalamus-pituitary-gonadal axis of CD-1 mice.

    Wei Xi;C.K.F. Lee;W.S.B. Yeung;John P. Giesy;John P. Giesy

  • Polybrominated diphenyl ethers and their hydroxylated/methoxylated analogs: environmental sources, metabolic relationships, and relative toxicities.

    Steve B. Wiseman;Yi Wan;Hong Chang;Xiaowei Zhang

  • The Role of Omics in the Application of Adverse Outcome Pathways for Chemical Risk Assessment

    Erica K Brockmeier;Geoff Hodges;Thomas H Hutchinson;Emma Butler

  • Endothelial cell spheroids as a versatile tool to study angiogenesis in vitro

    Maximilian Heiss;Mats Hellström;Mattias Kalén;Tobias May

  • The metabolism of L-arginine and its significance for the biosynthesis of endothelium-derived relaxing factor: L-glutamine inhibits the generation of L-arginine by cultured endothelial cells.

    William C. Sessa;Markus Hecker;Jane A. Mitchell;John R. Vane

  • Real-time PCR array to study effects of chemicals on the Hypothalamic-Pituitary-Gonadal axis of the Japanese medaka.

    Xiaowei Zhang;Markus Hecker;Markus Hecker;June-Woo Park;Amber R. Tompsett

  • Effects of prochloraz or propylthiouracil on the cross-talk between the HPG, HPA, and HPT axes in zebrafish.

    Chunsheng Liu;Xiaowei Zhang;Jun Deng;Markus Hecker

  • von Willebrand factor fibers promote cancer-associated platelet aggregation in malignant melanoma of mice and humans.

    Alexander T. Bauer;Jan Suckau;Kathrin Frank;Anna Desch

  • Effects of 20 PBDE metabolites on steroidogenesis in the H295R cell line

    Yuhe He;Margaret B. Murphy;Richard M.K. Yu;Michael H.W. Lam

  • Stretch-induced endothelin B receptor-mediated apoptosis in vascular smooth muscle cells

    Marco Cattaruzza;Caroline Dimigen;Hannelore Ehrenreich;Markus Hecker

  • Novel random peptide libraries displayed on AAV serotype 9 for selection of endothelial cell-directed gene transfer vectors

    K Varadi;S Michelfelder;T Korff;M Hecker

  • Bisphenol A Disrupts Steroidogenesis in Human H295R Cells

    Xiaowei Zhang;Hong Chang;Steve Wiseman;Yuhe He

  • Endothelial Microparticles From Acute Coronary Syndrome Patients Induce Premature Coronary Artery Endothelial Cell Aging and Thrombogenicity: Role of the Ang II/AT1 Receptor/NADPH Oxidase-Mediated Activation of MAPKs and PI3-Kinase Pathways

    Malak Abbas;Laurence Jesel;Cyril Auger;Lamia K. Amoura

  • Interconversion of hydroxylated and methoxylated polybrominated diphenyl ethers in Japanese medaka.

    Yi Wan;Fengyan Liu;Steve Wiseman;Xiaowei Zhang

  • Quantitative RT-PCR methods for evaluating toxicant-induced effects on steroidogenesis using the H295R cell line.

    Xiaowei Zhang;Richard M. K. Yu;Paul D. Jones;Gabriel K. W. Lam

  • Transcription factor decoy technology: A therapeutic update

    Markus Hecker;Andreas H. Wagner

  • Role of ephrinB2 expression in endothelial cells during arteriogenesis: impact on smooth muscle cell migration and monocyte recruitment.

    Thomas Korff;Jennifer Braun;Dennis Pfaff;Hellmut G. Augustin

  • Pathogenesis of varicose veins - lessons from biomechanics.

    Larissa Pfisterer;Gerd König;Markus Hecker;Thomas Korff

Frequent Co-Authors

Hellmut G. Augustin
Hellmut G. Augustin Heidelberg University
Peter P. Nawroth
Peter P. Nawroth Heidelberg University
Hugo A. Katus
Hugo A. Katus Heidelberg University
Thomas Giese
Thomas Giese Heidelberg University
Thomas Wieland
Thomas Wieland Heidelberg University
Christine S. Falk
Christine S. Falk Hannover Medical School
Anthony D. Ho
Anthony D. Ho University Hospital Heidelberg
Marc Freichel
Marc Freichel Heidelberg University
Jenny Chang-Claude
Jenny Chang-Claude German Cancer Research Center
Peter N. Robinson
Peter N. Robinson The Jackson Laboratory

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