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Medicine

D-Index
112
Citations
52599
World Ranking
5108
National Ranking
2761

Overview

Donald M. McDonald is affiliated with the University of California, San Francisco in the United States. Their research spans several fields within medicine and neuroscience, focusing particularly on aspects of cerebrospinal fluid dynamics, lymphatic system function, and barrier structures in vascular biology.

Their main fields of study include:

  • Medicine
  • Neuroscience

Within these fields, their work further specializes in subfields such as:

  • Neurology
  • Cellular and Molecular Neuroscience
  • Oncology
  • Molecular Biology
  • Physiology

Their research topics cover a range of biomedical issues, notably:

  • Cerebrospinal fluid and hydrocephalus
  • Lymphatic System and Diseases
  • Barrier Structure and Function Studies
  • Spinal Dysraphism and Malformations
  • Angiogenesis and VEGF in Cancer
  • Head and Neck Surgical Oncology
  • Erythrocyte Function and Pathophysiology

Donald M. McDonald has contributed to numerous scientific papers published in reputable venues. Some of the recent studies include:

  • Permeability of the Endothelial Barrier: Identifying and Reconciling Controversies, 2020, Trends in Molecular Medicine
  • Nasopharyngeal lymphatic plexus is a hub for cerebrospinal fluid drainage, 2024, Nature
  • Molecular anatomy of adult mouse leptomeninges, 2023, Neuron
  • Piezo1-Regulated Mechanotransduction Controls Flow-Activated Lymphatic Expansion, 2022, Circulation Research
  • Buttons and Zippers: Endothelial Junctions in Lymphatic Vessels, 2022, Cold Spring Harbor Perspectives in Medicine

Their frequent co-authors, indicating ongoing collaborative research efforts, include:

  • Peter Bałuk
  • Gou Young Koh
  • Steven T. Proulx
  • Britta Engelhardt
  • Christer Betsholtz

Donald M. McDonald's publications are regularly featured in journals such as:

  • Nature
  • American Journal Of Pathology
  • The Journal of Experimental Medicine
  • Nature Cardiovascular Research
  • Trends in Molecular Medicine

Best Publications

  • Openings between Defective Endothelial Cells Explain Tumor Vessel Leakiness

    Hiroya Hashizume;Peter Baluk;Shunichi Morikawa;John W. McLean

  • Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1.

    G. Thurston;C. Suri;K. Smith;J. McClain

  • Angiopoietin-1 protects the adult vasculature against plasma leakage.

    Gavin Thurston;John S. Rudge;Ella Ioffe;Hao Zhou

  • Imaging of angiogenesis: from microscope to clinic

    Donald M McDonald;Peter L Choyke

  • Abnormalities in Pericytes on Blood Vessels and Endothelial Sprouts in Tumors

    Shunichi Morikawa;Peter Baluk;Toshiyuki Kaidoh;Amy Haskell

  • Mechanisms of adverse effects of anti-VEGF therapy for cancer

    T Kamba;D M McDonald

  • Inhibition of Vascular Endothelial Growth Factor (VEGF) Signaling in Cancer Causes Loss of Endothelial Fenestrations, Regression of Tumor Vessels, and Appearance of Basement Membrane Ghosts

    Tetsuichiro Inai;Michael Mancuso;Hiroya Hashizume;Fabienne Baffert

  • Functionally specialized junctions between endothelial cells of lymphatic vessels

    Peter Baluk;Jonas Fuxe;Jonas Fuxe;Hiroya Hashizume;Hiroya Hashizume;Talia Romano;Talia Romano

  • Increased Vascularization in Mice Overexpressing Angiopoietin-1

    Chitra Suri;Joyce McClain;Gavin Thurston;Donald M. McDonald

  • Cellular abnormalities of blood vessels as targets in cancer.

    Peter Baluk;Hiroya Hashizume;Donald M McDonald

  • Rapid vascular regrowth in tumors after reversal of VEGF inhibition

    Michael R. Mancuso;Rachel Davis;Scott M. Norberg;Shaun O’Brien

  • Mosaic blood vessels in tumors: Frequency of cancer cells in contact with flowing blood

    Yong S. Chang;Emmanuelle di Tomaso;Donald M. McDonald;Rosemary Jones

  • Signalling via vascular endothelial growth factor receptor‐3 is sufficient for lymphangiogenesis in transgenic mice

    Tanja Maaret Veikkola;Lotta Jussila;Taija Marianna Mäkinen;Terhi Hannele Kärpänen

  • VEGF-dependent plasticity of fenestrated capillaries in the normal adult microvasculature

    Tomomi Kamba;Betty Y. Y. Tam;Hiroya Hashizume;Amy Haskell

  • Vascular endothelial–cadherin is an important determinant of microvascular integrity in vivo

    Monica Corada;Massimo Mariotti;Gavin Thurston;Kelly Smith

  • Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung.

    Chun Geun Lee;Holger Link;Peter Baluk;Robert J Homer

  • Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation

    Peter Baluk;Tuomas Tammela;Erin Ator;Natalya Lyubynska

  • Abnormalities of basement membrane on blood vessels and endothelial sprouts in tumors.

    Peter Baluk;Shunichi Morikawa;Amy Haskell;Michael Mancuso

  • Microenvironmental VEGF concentration, not total dose, determines a threshold between normal and aberrant angiogenesis.

    Clare R. Ozawa;Andrea Banfi;Nicole L. Glazer;Gavin Thurston

  • Significance of Blood Vessel Leakiness in Cancer

    Donald M McDonald;Peter Baluk

Frequent Co-Authors

Bedangadas Mohanty
Bedangadas Mohanty National Institute of Science Education and Research
Zubayer Ahammed
Zubayer Ahammed Variable Energy Cyclotron Centre
Madan M. Aggarwal
Madan M. Aggarwal Panjab University
M. A. Lisa
M. A. Lisa The Ohio State University
R. P. Scharenberg
R. P. Scharenberg Purdue University West Lafayette
H. Caines
H. Caines Yale University
Sergey Voloshin
Sergey Voloshin Wayne State University
Shaojun Li
Shaojun Li Chinese Academy of Sciences
Nu Xu
Nu Xu Lawrence Berkeley National Laboratory
P. Filip
P. Filip Warsaw University of Technology

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