World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
42
Citations
9077
World Ranking
3008
National Ranking
1430

Overview

David J. Steger is affiliated with the University of Pennsylvania in the United States and works primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research spans diverse subfields, including Physiology, Molecular Biology, Biochemistry, Epidemiology, and Surgery.

Their scientific contributions focus on topics such as Adipose Tissue and Metabolism, Peroxisome Proliferator-Activated Receptors, Lipid metabolism and biosynthesis, Adipokines, Inflammation, and Metabolic Diseases, Lipid metabolism and disorders, Epigenetics and DNA Methylation, and Bladder and Urothelial Cancer Treatments.

Recent published works by David J. Steger include:

  • Shared PPARα/γ Target Genes Regulate Brown Adipocyte Thermogenic Function (2020, Cell Reports)
  • Isoform-specific functions of PPARγ in gene regulation and metabolism (2022, Genes & Development)
  • Cell-Intrinsic Tumorigenic Functions of PPARγ in Bladder Urothelial Carcinoma (2021, Molecular Cancer Research)
  • Isotopically characterised N 2 O reference materials for use as community standards (2022, Rapid Communications in Mass Spectrometry)
  • Transcriptional regulation of adipocyte lipolysis by IRF2BP2 (2025, Science Advances)

Frequent collaborators in their research include Patrick Seale, Ryan Calhoun, Mitchell A. Lazar, Raymond E. Soccio, and Yang Chen.

David J. Steger has contributed to multiple publication venues, notably:

  • Genes & Development
  • Cell Reports
  • Molecular Cancer Research
  • Rapid Communications in Mass Spectrometry
  • Science Advances

Best Publications

  • PPARγ and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale

    Martina I. Lefterova;Yong Zhang;David J. Steger;Michael Schupp

  • Transcriptional activators direct histone acetyltransferase complexes to nucleosomes

    Rhea T. Utley;Keiko Ikeda;Patrick A. Grant;Jacques Côté

  • A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation.

    Patrick A Grant;Patrick A Grant;David Schieltz;Marilyn G Pray-Grant;Marilyn G Pray-Grant;David J Steger;David J Steger

  • DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells.

    David J. Steger;Martina I. Lefterova;Lei Ying;Aaron J. Stonestrom

  • Regulation of Chromatin Remodeling by Inositol Polyphosphates

    David J. Steger;Elizabeth S. Haswell;Aimee L. Miller;Susan R. Wente

  • Activation Domain–Mediated Targeting of the SWI/SNF Complex to Promoters Stimulates Transcription from Nucleosome Arrays

    Kristen E Neely;Ahmed H Hassan;Annika E Wallberg;David J Steger

  • Chromatin decouples promoter threshold from dynamic range.

    Felix H. Lam;David J. Steger;David J. Steger;Erin K. O’Shea

  • Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation

    Shannon E. Mullican;Christine A. Gaddis;Theresa Alenghat;Meera G. Nair

  • Discrete functions of nuclear receptor Rev-erbα couple metabolism to the clock

    Yuxiang Zhang;Bin Fang;Matthew J. Emmett;Manashree Damle

  • Propagation of adipogenic signals through an epigenomic transition state

    David J. Steger;Gregory R. Grant;Michael Schupp;Takuya Tomaru

  • Cell-Specific Determinants of Peroxisome Proliferator-Activated Receptor γ Function in Adipocytes and Macrophages

    Martina I. Lefterova;David J. Steger;David Zhuo;Mohammed Qatanani

  • GATA-binding proteins regulate the human gonadotropin alpha-subunit gene in the placenta and pituitary gland.

    D J Steger;J H Hecht;P L Mellon

  • The chromo domain protein chd1p from budding yeast is an ATP-dependent chromatin-modifying factor.

    Hien G Tran;David J Steger;Vishwanath R Iyer;Alexander D Johnson

  • Activation Domain-Specific and General Transcription Stimulation by Native Histone Acetyltransferase Complexes

    Keiko Ikeda;David J. Steger;Anton Eberharter;Jerry L. Workman

  • Rev-erbα dynamically modulates chromatin looping to control circadian gene transcription.

    Yong Hoon Kim;Sajid A. Marhon;Yuxiang Zhang;David J. Steger

  • Diet-Induced Circadian Enhancer Remodeling Synchronizes Opposing Hepatic Lipid Metabolic Processes

    Dongyin Guan;Ying Xiong;Patricia C. Borck;Cholsoon Jang

  • Purified histone acetyltransferase complexes stimulate HIV-1 transcription from preassembled nucleosomal arrays

    David J. Steger;Anton Eberharter;Sam John;Patrick A. Grant

  • Genomic redistribution of GR monomers and dimers mediates transcriptional response to exogenous glucocorticoid in vivo

    Hee-Woong Lim;N. Henriette Uhlenhaut;Alexander Rauch;Juliane Weiner

  • Identification and Characterization of a Selective Peroxisome Proliferator-Activated Receptor β/δ (NR1C2) Antagonist

    Barry G. Shearer;David J. Steger;James M. Way;Thomas B. Stanley

  • Distribution of acetylated histones resulting from Gal4-VP16 recruitment of SAGA and NuA4 complexes.

    Marissa Vignali;David J. Steger;Kristen E. Neely;Jerry L. Workman

Frequent Co-Authors

Mitchell A. Lazar
Mitchell A. Lazar University of Pennsylvania
Jerry L. Workman
Jerry L. Workman Stowers Institute for Medical Research
Pamela L. Mellon
Pamela L. Mellon University of California, San Diego
Sam John
Sam John National Institutes of Health
Patrick A. Grant
Patrick A. Grant University of Virginia
Jonathan Schug
Jonathan Schug University of Pennsylvania
Erin K. O'Shea
Erin K. O'Shea Howard Hughes Medical Institute
Christopher S. Chen
Christopher S. Chen Boston University
Jacques Côté
Jacques Côté Université Laval
Tom Owen-Hughes
Tom Owen-Hughes University of Dundee

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring a degree in Molecular Biology can open doors to several health and science careers—many of which now offer flexible, online pathways. For students considering a shift to allied health fields, a popular route is the SLP bridge pathway for communication sciences graduates. This allows those with a science background to move into speech-language pathology with targeted online coursework.

Aspiring nurses from non-nursing backgrounds can leverage online absn programs for non nurses to earn a Bachelor of Science in Nursing quickly and conveniently. Graduates often move on to advanced practice roles, such as nurse practitioners.

If you're considering becoming a nurse practitioner, you may wonder about how many years to become a nurse practitioner and the potential career outlook. Specializing further, such as in psychiatric nursing, can significantly increase earning potential—learn more about psychiatric np salary by state.

These online programs and alternative pathways highlight the versatility of a Molecular Biology degree, helping students transition into high-demand health professions through accelerated, flexible study options.

Best Scientists Citing David J. Steger

Trending Scientists