World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
76
Citations
20058
World Ranking
5062
National Ranking
2427

Research.com Recognitions

  • 2019 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Pamela L. Mellon is affiliated with the University of California, San Diego in the United States. Their research spans multiple fields, primarily focusing on medicine and biochemistry, genetics, and molecular biology. They have contributed extensively to the subfields of reproductive medicine, molecular biology, public health, environmental and occupational health, endocrine and autonomic systems, and genetics.

Their scientific investigations cover main topics such as hypothalamic control of reproductive hormones, ovarian function and disorders, circadian rhythm and melatonin, reproductive biology and fertility, genetic and clinical aspects of sex determination and chromosomal abnormalities, neuroendocrine regulation and behavior, and plant reproductive biology.

Recent published papers by Pamela L. Mellon include:

  • Initiation of Parental Genome Reprogramming in Fertilized Oocyte by Splicing Kinase SRPK1-Catalyzed Protamine Phosphorylation, 2020, Cell
  • Reproductive Deficits Induced by Prenatal Antimüllerian Hormone Exposure Require Androgen Receptor in Kisspeptin Cells, 2021, Endocrinology
  • FSHB Transcription is Regulated by a Novel 5' Distal Enhancer With a Fertility-Associated Single Nucleotide Polymorphism, 2020, Endocrinology
  • Circadian Rhythms in the Neuronal Network Timing the Luteinizing Hormone Surge, 2021, Endocrinology
  • The transcription factors SIX3 and VAX1 are required for suprachiasmatic nucleus circadian output and fertility in female mice, 2021, Journal of Neuroscience Research

Coauthors frequently collaborating with Pamela L. Mellon include:

  • Karen J. Tonsfeldt
  • Jessica Cassin
  • Hanne M. Hoffmann
  • Stephanie C. Bohaczuk
  • Varykina G. Thackray

Key publication venues for Pamela L. Mellon are:

  • Journal of the Endocrine Society
  • Endocrinology
  • Molecular and Cellular Endocrinology
  • Frontiers in Endocrinology
  • Cell

In 2019, Pamela L. Mellon was recognized as a Fellow of the American Association for the Advancement of Science (AAAS).

Best Publications

  • Immortalization of hypothalamic GnRH by genetically targeted tumorigenesis

    Pamela L. Mellon;Jolene J. Windle;Paul C. Goldsmith;Cheryl A. Padula

  • Identification of DNA sequences required for transcription of the human α1-globin gene in a new SV40 host-vector system

    Pamela Mellon;Pamela Mellon;Vann Parker;Yakov Gluzman;Tom Maniatis;Tom Maniatis

  • Cell lines of the pituitary gonadotrope lineage derived by targeted oncogenesis in transgenic mice.

    Jolene J. Windle;Richard I. Weiner;Pamela L. Mellon

  • Negative regulation by glucocorticoids through interference with a cAMP responsive enhancer

    Ingrid E. Akerblom;Emily P. Slater;Miguel Beato;John D. Baxter

  • Tissue-specific enhancer of the human glycoprotein hormone alpha-subunit gene: dependence on cyclic AMP-inducible elements.

    A M Delegeane;L H Ferland;P L Mellon

  • Induction of proto-oncogene fos transcription through the adenylate cyclase pathway: characterization of a cAMP-responsive element.

    P Sassone-Corsi;J Visvader;L Ferland;P L Mellon

  • Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice

    Xuchu Que;Ming Yow Hung;Ming Yow Hung;Calvin Yeang;Ayelet Gonen

  • Cloning and functional expression of a mouse gonadotropin-releasing hormone receptor

    Manami Tsutsumi;Wei Zhou;Robert P. Millar;Pamela L. Mellon

  • Immortalization of pituitary cells at discrete stages of development by directed oncogenesis in transgenic mice

    Elaine T. Alarid;Jolene J. Windle;David B. Whyte;Pamela L. Mellon

  • Intrinsic pulsatile secretory activity of immortalized luteinizing hormone-releasing hormone-secreting neurons.

    William C. Wetsel;Marcelo M. Valenca;Istvan Merchenthaler;Zsolt Liposits

  • Differences in human α- and β-globin gene expression in mouse erythroleukemia cells: The role of intragenic sequences

    Patrick Charnay;Richard Treisman;Pamela Mellon;Moses Chao

  • The orphan nuclear receptor, steroidogenic factor-1, regulates the glycoprotein hormone alpha-subunit gene in pituitary gonadotropes.

    Kerry M. Barnhart;Pamela L. Mellon

  • Steroid and pulsatile gonadotropin-releasing hormone (GnRH) regulation of luteinizing hormone and GnRH receptor in a novel gonadotrope cell line

    Judith L. Turgeon;Yuka Kimura;Dennis W. Waring;Pamela L. Mellon

  • Regulation of transcription by cyclic AMP-dependent protein kinase.

    P L Mellon;C H Clegg;L A Correll;G S McKnight

  • Retinoblastoma in transgenic mice.

    Jolene J. Windle;Daniel M. Albert;Joan M. O'Brien;Dennis M. Marcus

  • Loss-of-function mutation in the prokineticin 2 gene causes Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism

    Nelly Pitteloud;Chengkang Zhang;Duarte Pignatelli;Jia-Da Li

  • GnRH Activates ERK1/2 Leading to the Induction of c-fos and LHβ Protein Expression in LβT2 Cells

    Fujun Liu;Darrell A. Austin;Pamela L. Mellon;Jerrold M. Olefsky

  • Cell-specific transcriptional regulation of follicle-stimulating hormone-beta by activin and gonadotropin-releasing hormone in the LbetaT2 pituitary gonadotrope cell model.

    Flavia Pernasetti;Vyacheslav V. Vasilyev;Suzanne B. Rosenberg;Janice S. Bailey

  • Involvement of Both Gq/11 and Gs Proteins in Gonadotropin-releasing Hormone Receptor-mediated Signaling in LβT2 Cells *

    Fujun Liu;Isao Usui;Lui Guojing Evans;Darrell A. Austin

  • GATA-binding proteins regulate the human gonadotropin alpha-subunit gene in the placenta and pituitary gland.

    D J Steger;J H Hecht;P L Mellon

Frequent Co-Authors

Nicholas J. G. Webster
Nicholas J. G. Webster University of California, San Diego
Tom Maniatis
Tom Maniatis Columbia University
William C. Wetsel
William C. Wetsel Duke University
Patrick Charnay
Patrick Charnay École Normale Supérieure
Jerrold M. Olefsky
Jerrold M. Olefsky University of California, San Diego
David J. Steger
David J. Steger University of Pennsylvania
Moses V. Chao
Moses V. Chao New York University
Peter H. Duesberg
Peter H. Duesberg University of California, Berkeley
Richard Axel
Richard Axel Columbia University
Andres Negro-Vilar
Andres Negro-Vilar National Institutes of Health

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