World's Best Scientists 2026 revealed!
Award Badge
Best Scientists
2025
Award Badge
Molecular Biology
USA
2026

D-Index & Metrics

Best Scientists

D-Index
170
Citations
321105
World Ranking
848
National Ranking
508

Molecular Biology

D-Index
170
Citations
321766
World Ranking
45
National Ranking
31

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Molecular Biology in United States Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in United States Leader Award
  • 2023 - Research.com Molecular Biology in United States Leader Award
  • 2012 - Member of the National Academy of Medicine (NAM)
  • 2008 - National Institutes of Health Director's Pioneer Award
  • 2001 - Robert J. and Claire Pasarow Foundation Medical Research Award
  • 2000 - AMA Scientific Achievement Award, American Medical Association
  • 1986 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1985 - Fellow of the American Academy of Arts and Sciences
  • 1985 - Member of the National Academy of Sciences
  • 1985 - Richard Lounsbery Award, National Academy of Sciences and the French Academy of Sciences for their seminal contributions to our understanding of the structure and function of DNA which were essential and fundamental to the development of recombinant DNA techniques.

Overview

Tom Maniatis is affiliated with Columbia University in the United States and has a research focus predominantly in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several subfields including Molecular Biology, Infectious Diseases, Epidemiology, Immunology, and Genetics.

The main topics Maniatis has contributed to include SARS-CoV-2 and COVID-19 Research, Respiratory Viral Infections Research, Amyotrophic Lateral Sclerosis Research, COVID-19 Clinical Research Studies, interferon and immune responses, Neuroscience and Neuropharmacology Research, and Immunodeficiency and Autoimmune Disorders.

Maniatis has published multiple papers in various notable venues. Some recent papers include:

  • Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children (2022) - Science
  • Studying severe long COVID to understand post-infectious disorders beyond COVID-19 (2022) - Nature Medicine
  • Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia (2022) - The Journal of Experimental Medicine
  • The Loss of TBK1 Kinase Activity in Motor Neurons or in All Cell Types Differentially Impacts ALS Disease Progression in SOD1 Mice (2020) - Neuron
  • Autoantibodies against type I IFNs in patients with critical influenza pneumonia (2022) - The Journal of Experimental Medicine

Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Experimental Medicine
  • Neuron
  • Genome Medicine
  • Cell

Frequent co-authors collaborating with Maniatis are:

  • Andrés A. Arias
  • Filomeen Haerynck
  • Rebeca Pérez de Diego
  • Giorgio Casari
  • Yenan T. Bryceson

Throughout their career, Maniatis has received several awards including recognition as a Member of the National Academy of Medicine in 2012 and Member of the National Academy of Sciences and Fellow of the American Academy of Arts and Sciences in 1985. Additional honors include the National Institutes of Health Director's Pioneer Award in 2008, the Robert J. and Claire Pasarow Foundation Medical Research Award in 2001, the AMA Scientific Achievement Award in 2000, Fellowship in the American Association for the Advancement of Science in 1986, and the Richard Lounsbery Award jointly from the National Academy of Sciences and the French Academy of Sciences in 1985 for contributions to understanding DNA structure and function relevant to recombinant DNA technology.

Best Publications

  • Molecular Cloning: A Laboratory Manual

    Joseph Sambrook;E. F. Fritsch;Tom Maniatis

  • Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

    D.A. Melton;P.A. Krieg;M.R. Rebagliati;T. Maniatis

  • An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

    Ye Zhang;Kenian Chen;Steven A Sloan;Mariko L Bennett

  • IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.

    Katherine A. Fitzgerald;Sarah M. McWhirter;Kerrie L. Faia;Daniel C. Rowe

  • The ubiquitinproteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB

    Vito J. Palombella;Oliver J. Rando;Alfred L. Goldberg;Tom Maniatis

  • Nucleotide sequence of the rightward operator of phage lambda

    Tom Maniatis;Andrea Jeffrey;Dennis G. Kleid

  • Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers.

    Tucker Collins;Margaret A. Read;Andrew S. Neish;Maryann Z. Whitley

  • Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

    Qian Zhang;Paul Bastard;Paul Bastard;Zhiyong Liu;Jérémie Le Pen

  • The isolation of structural genes from libraries of eucaryotic DNA

    Tom Maniatis;Ross C. Hardison;Elizabeth Lacy;Joyce Lauer

  • Regulation of inducible and tissue-specific gene expression

    Tom Maniatis;Stephen Goodbourn;Janice A. Fischer

  • Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway.

    Zhijian Chen;J. Hagler;V. J. Palombella;F. Melandri

  • NF-κB: A lesson in family values

    Dimitris Thanos;Tom Maniatis

  • The structure and evolution of the human β-globin gene family

    Argiris Efstratiadis;James W. Posakony;Tom Maniatis;Richard M. Lawn

  • Transformation of mammalian cells with genes from procaryotes and eucaryotes

    Michael Wigler;Raymond Sweet;Gek Kee Sim;Barbara Wold

  • The MicroRNA miR-124 Promotes Neuronal Differentiation by Triggering Brain-Specific Alternative Pre-mRNA Splicing

    Eugene V. Makeyev;Jiangwen Zhang;Monica A. Carrasco;Tom Maniatis

  • Transcriptional activation: A complex puzzle with few easy pieces

    Robert Tjian;Tom Maniatis

  • An extensive network of coupling among gene expression machines

    Tom Maniatis;Robin Reed

  • Site-Specific Phosphorylation of IκBα by a Novel Ubiquitination-Dependent Protein Kinase Activity

    Zhijian J Chen;Lana Parent;Tom Maniatis

  • Virus induction of human IFNβ gene expression requires the assembly of an enhanceosome

    Dimitris Thanos;Tom Maniatis

  • Chain length determination of small double- and single-stranded DNA molecules by polyacrylamide gel electrophoresis

    T Maniatis;A Jeffrey;H van deSande

Frequent Co-Authors

Argiris Efstratiadis
Argiris Efstratiadis Biomedical Research Foundation of the Academy of Athens
Oliver J. Rando
Oliver J. Rando University of Massachusetts Chan Medical School
Barry Honig
Barry Honig Columbia University
Richard Axel
Richard Axel Columbia University
Dimitris Thanos
Dimitris Thanos Academy of Athens
Richard Treisman
Richard Treisman The Francis Crick Institute
Robin Reed
Robin Reed Harvard University
Mark Ptashne
Mark Ptashne Memorial Sloan Kettering Cancer Center
Lawrence Shapiro
Lawrence Shapiro Columbia University
Richard M. Myers
Richard M. Myers HudsonAlpha Institute for Biotechnology

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Molecular Biology in the USA opens up a variety of educational and professional opportunities, especially when combined with interdisciplinary online degrees. For those interested in the intersection of biology and psychology or law, understanding what can I do with a forensic psychology degree can help you explore roles in crime labs, legal consulting, or public policy.

Students passionate about developmental science may consider an online child psychology master's to work with younger populations or design research addressing genetic influences on behavior. Meanwhile, an online master's in counseling can lead to careers that blend biological understanding with mental health intervention.

Additionally, earning a degree through clinical psychology online degree programs can enable scientific professionals to contribute to therapy development or become specialists in neurobiological disorders. These interdisciplinary pathways can enhance your career prospects within biomedical, academic, or clinical settings.

Best Scientists Citing Tom Maniatis

Trending Scientists

Recently Published Articles