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Biology and Biochemistry

D-Index
55
Citations
10831
World Ranking
15058
National Ranking
6302

Overview

Nicholas J. G. Webster is affiliated with the University of California, San Diego in the United States. Their research spans fields related to biochemistry, genetics, molecular biology, and medicine, with a particular focus on subfields including molecular biology, physiology, immunology, endocrine and autonomic systems, and cancer research.

The scientist's work covers key topics such as RNA research and splicing, RNA modifications and cancer, dietary effects on health, diet and metabolism studies, circadian rhythm and melatonin, adipose tissue and metabolism, and cancer-related molecular mechanisms research.

Recent publications authored or co-authored by this researcher include:

  • Time-restricted feeding normalizes hyperinsulinemia to inhibit breast cancer in obese postmenopausal mouse models, 2021, Nature Communications
  • Mitochondrial Dysfunction in Obesity and Reproduction, 2020, Endocrinology
  • Immunosuppression of Macrophages Underlies the Cardioprotective Effects of CST (Catestatin), 2021, Hypertension
  • Hepatocyte Deletion of IGF2 Prevents DNA Damage and Tumor Formation in Hepatocellular Carcinoma, 2022, Advanced Science
  • Alternative RNA Splicing in Fatty Liver Disease, 2021, Frontiers in Endocrinology

Frequent co-authors working with Nicholas J. G. Webster include Manasi Das, Sushil K. Mahata, Kechun Tang, Gautam Bandyopadhyay, and Eyal Raz.

The researcher has contributed publications across various fields by appearing in journals and venues such as bioRxiv (Cold Spring Harbor Laboratory), International Journal for Population Data Science, Frontiers in Genetics, Journal of Vascular and Interventional Radiology, and Nature Communications.

Best Publications

  • The human estrogen receptor has two independent nonacidic transcriptional activation functions.

    Laszio Tora;John White;Christel Brou;Dlane Tasset

  • The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function

    Nicholas J.G. Webster;Stephen Green;Jia Rui Jin;Pierre Chambon

  • The Yeast UASG Is a Transcriptional Enhancer in Human HeLa Cells in the Presence of the GAL4 Trans-Activator

    Nicholas Webster;Jia Rui Jin;Stephen Green;Melvyn Hollis

  • GnRH pulsatility, the pituitary response and reproductive dysfunction.

    Rie Tsutsumi;Rie Tsutsumi;Rie Tsutsumi;Nicholas J.G. Webster;Nicholas J.G. Webster

  • Brain PPAR-γ promotes obesity and is required for the insulin–sensitizing effect of thiazolidinediones

    Min Min Lu;David A. Sarruf;Saswata Talukdar;Shweta Sharma;Shweta Sharma

  • GnRH Activates ERK1/2 Leading to the Induction of c-fos and LHβ Protein Expression in LβT2 Cells

    Fujun Liu;Darrell A. Austin;Pamela L. Mellon;Jerrold M. Olefsky

  • Involvement of Both Gq/11 and Gs Proteins in Gonadotropin-releasing Hormone Receptor-mediated Signaling in LβT2 Cells *

    Fujun Liu;Isao Usui;Lui Guojing Evans;Darrell A. Austin

  • Curcumin disrupts the Mammalian target of rapamycin-raptor complex

    Christopher S. Beevers;Long Chen;Lei Liu;Yan Luo

  • Elevated Insulin-like Growth Factor I Receptor Autophosphorylation and Kinase Activity in Human Breast Cancer

    J. L. Resnik;D. B. Reichart;Kim Huey;N. J. G. Webster

  • A Novel Letrozole Model Recapitulates Both the Reproductive and Metabolic Phenotypes of Polycystic Ovary Syndrome in Female Mice.

    Alexander S. Kauffman;Varykina G. Thackray;Genevieve E. Ryan;Kristen P. Tolson

  • Repression of the insulin receptor promoter by the tumor suppressor gene product p53: a possible mechanism for receptor overexpression in breast cancer.

    N. J. G. Webster;J. L. Resnik;D. B. Reichart;B. Strauss

  • Adiponectin Activates Adenosine Monophosphate-Activated Protein Kinase and Decreases Luteinizing Hormone Secretion in LβT2 Gonadotropes

    Min Lu;Qingbo Tang;Jerrold M. Olefsky;Pamela L. Mellon

  • Molecular Tumor Board: The University of California San Diego Moores Cancer Center Experience

    Maria Schwaederle;Barbara A. Parker;Richard B. Schwab;Paul T. Fanta

  • Adiponectin Blocks Interleukin-18-mediated Endothelial Cell Death via APPL1-dependent AMP-activated Protein Kinase (AMPK) Activation and IKK/NF-κB/PTEN Suppression *

    Bysani Chandrasekar;William H. Boylston;Kaliyamurthi Venkatachalam;Nicholas J.G. Webster

  • Mucosal adjuvant activity of cholera toxin requires Th17 cells and protects against inhalation anthrax.

    Sandip K. Datta;Mojgan Sabet;Kim Phung L. Nguyen;Patricia A. Valdez

  • Interaction of musleblind, CUG‐BP1 and hnRNP H proteins in DM1‐associated aberrant IR splicing

    Sharan Paul;Warunee Dansithong;Dongho Kim;John Rossi

  • Splicing factor SRSF3 is crucial for hepatocyte differentiation and metabolic function

    Supriya Sen;Hassan Jumaa;Nicholas J. G. Webster

  • Effect of dexamethasone on the alternative splicing of the insulin receptor mRNA and insulin action in HepG2 hepatoma cells.

    A. Kosaki;N. J. G. Webster

  • Time-restricted feeding improves insulin resistance and hepatic steatosis in a mouse model of postmenopausal obesity

    Heekyung Chung;Winjet Chou;Dorothy D. Sears;Ruth E. Patterson

  • A domain of the insulin receptor required for endocytosis in rat fibroblasts.

    R S Thies;N J Webster;D A McClain

Frequent Co-Authors

Jerrold M. Olefsky
Jerrold M. Olefsky University of California, San Diego
Sushil K. Mahata
Sushil K. Mahata University of California, San Diego
Allen F. Ryan
Allen F. Ryan University of California, San Diego
Pamela L. Mellon
Pamela L. Mellon University of California, San Diego
Michael C. Pirrung
Michael C. Pirrung University of California, Riverside
Lesley G. Ellies
Lesley G. Ellies University of California, San Diego
Stephen I. Wasserman
Stephen I. Wasserman University of California, San Diego
Maripat Corr
Maripat Corr University of California, San Diego
Hemal H. Patel
Hemal H. Patel University of California, San Diego
Paul A. Insel
Paul A. Insel University of California, San Diego

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